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TFEB elisa kit :: Mouse transcription factor EB ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9328687 TFEB elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

transcription factor EB (TFEB), ELISA Kit

 Also Known As   

Mouse Transcription factor EB, TFEB ELISA Kit

 Product Synonym Names    Mouse Transcription factor EB (TFEB) ELISA kit; RP4-696P19.3; ALPHATFEB; BHLHE35; TCFEB; OTTHUMP00000043540; T-cell transcription factor EB; transcription factor EB
 Product Gene Name   

TFEB elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 3D Structure    ModBase 3D Structure for Q9R210
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of TFEB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TFEB purchase    MBS9328687 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the transcription factor EB (TFEB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TFEB. The ELISA analytical biochemical technique of the MBS9328687 kit is based on TFEB antibody-TFEB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TFEB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TFEB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TFEB. It may not necessarily be applicable to this product.
 NCBI GI #    239835746
 NCBI GeneID    21425
 NCBI Accession #    NP_001155194.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001161722.1 [Other Products]
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 UniProt Primary Accession #    Q9R210 [Other Products]
 UniProt Related Accession #    Q9R210 [Other Products]
 Molecular Weight    52,614 Da
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 NCBI Official Full Name    transcription factor EB isoform b
 NCBI Official Synonym Full Names    transcription factor EB
 NCBI Official Symbol    Tfeb [Similar Products]
 NCBI Official Synonym Symbols   
Tcfeb; bHLHe35
[Similar Products]
 NCBI Protein Information    transcription factor EB
 UniProt Protein Name    Transcription factor EB
 Protein Family    Transcription factor
 UniProt Gene Name    Tfeb [Similar Products]
 UniProt Synonym Gene Names    Tcfeb [Similar Products]
 UniProt Entry Name    TFEB_MOUSE
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 UniProt Comments for TFEB    TFEB: Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta. Homodimer and heterodimer; with TFE3 or MITF. Belongs to the MiT/TFE family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Cellular Component: transcription factor complex; cytoplasm; nucleus

Molecular Function: protein dimerization activity; DNA binding; protein heterodimerization activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; embryonic placenta development; transcription, DNA-dependent; regulation of transcription, DNA-dependent; lysosome organization and biogenesis; immune system process; positive regulation of transcription, DNA-dependent; autophagy; positive regulation of transcription from RNA polymerase II promoter; humoral immune response; positive regulation of autophagy
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 Research Articles on TFEB    1. Overexpression of TFEB in a new muscle cell culture system and in mouse models of the disease reduced glycogen load and lysosomal size, improved autophagosome processing, and alleviated excessive accumulation of autophagic vacuoles.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with TFEB elisa kitDiseases associated with TFEB elisa kit
 Products by Pathway  Pathway Diagram
 PluriNetWork Pathway antibodies  PluriNetWork Pathway Diagram
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >36 publications with TFEB and Carcinoma
 Neoplasms Antibodies  >35 publications with TFEB and Neoplasms
 Kidney Diseases Antibodies  >30 publications with TFEB and Kidney Diseases
 Adenocarcinoma Antibodies  >28 publications with TFEB and Adenocarcinoma
 Translocation, Genetic Antibodies  >26 publications with TFEB and Translocation, Genetic
 Death Antibodies  >8 publications with TFEB and Death
 Heart Diseases Antibodies  >6 publications with TFEB and Heart Diseases
 Nervous System Diseases Antibodies  >4 publications with TFEB and Nervous System Diseases
 Myocardial Ischemia Antibodies  >4 publications with TFEB and Myocardial Ischemia
 Cell Transformation, Neoplastic Antibodies  >2 publications with TFEB and Cell Transformation, Neoplastic
Organs/Tissues associated with TFEB elisa kit
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >32 publications with TFEB and Kidney
 Muscle Antibodies  >6 publications with TFEB and Muscle
 Embryonic Tissue Antibodies  >5 publications with TFEB and Embryonic Tissue
 Liver Antibodies  >3 publications with TFEB and Liver
 Lymph Node Antibodies  >3 publications with TFEB and Lymph Node
 Brain Antibodies  >2 publications with TFEB and Brain
 Joint Antibodies  >1 publications with TFEB and Joint
 Intestine Antibodies  >1 publications with TFEB and Intestine
 Extraembryonic Tissue Antibodies  >1 publications with TFEB and Extraembryonic Tissue
 Skin Antibodies  >1 publications with TFEB and Skin
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