NP_659567.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
90,663 Da
NCBI Official Full Name
transient receptor potential cation channel subfamily V member 3
NCBI Official Synonym Full Names
transient receptor potential cation channel, subfamily V, member 3
NCBI Official Synonym Symbols
Nh; VRL3; AI644701; 1110036I10Rik [Similar Products]
NCBI Protein Information
transient receptor potential cation channel subfamily V member 3; non-hair; TRP ion channel TRPV3
UniProt Protein Name
Transient receptor potential cation channel subfamily V member 3
UniProt Synonym Gene Names
UniProt Entry Name
TRPV3_MOUSE
UniProt Comments for TRPV3
TRPV3: Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen). May form a heteromeric channel with TRPV1. Interacts with TRPV1. Abundantly expressed in CNS. Widely expressed at low levels. Detected in dorsal root ganglion. Expressed in the keratinocyte layers of the outer root sheath and, to lesser extent, to the matrix of the hair follicles. Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV3 sub-subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, cation
Cellular Component: membrane; integral to membrane; receptor complex
Molecular Function: protein binding; calcium channel activity; ion channel activity; cation channel activity
Biological Process: response to temperature stimulus; negative regulation of hair cycle; transport; calcium ion transport; ion transport; transmembrane transport
Research Articles on TRPV3
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Diseases associated with TRPV3 elisa kit
Organs/Tissues associated with TRPV3 elisa kit
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