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TMEM67 elisa kit :: Mouse transmembrane protein 67 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9334739 TMEM67 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

transmembrane protein 67 (TMEM67), ELISA Kit

 Also Known As   

Mouse Meckelin, TMEM67 ELISA Kit

 Product Synonym Names    Mouse Meckelin (TMEM67) ELISA kit; JBTS6; MECKELIN; MGC26979; MKS3; TNEM67; meckelin; transmembrane protein 67
 Product Gene Name   

TMEM67 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q8BR76
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TMEM67 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TMEM67 purchase    MBS9334739 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the transmembrane protein 67 (TMEM67) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TMEM67. The ELISA analytical biochemical technique of the MBS9334739 kit is based on TMEM67 antibody-TMEM67 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TMEM67 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TMEM67. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TMEM67. It may not necessarily be applicable to this product.
 NCBI GI #    240255631
 NCBI GeneID    329795
 NCBI Accession #    NP_808529.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_177861.4 [Other Products]
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 UniProt Primary Accession #    Q8BR76 [Other Products]
 UniProt Secondary Accession #    Q78U07 [Other Products]
 UniProt Related Accession #    Q8BR76 [Other Products]
 Molecular Weight    111,810 Da
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 NCBI Official Full Name    Meckelin
 NCBI Official Synonym Full Names    transmembrane protein 67
 NCBI Official Symbol    Tmem67 [Similar Products]
 NCBI Official Synonym Symbols   
B230117O07; b2b1163.1Clo; b2b1291.1Clo; 5330408M12Rik
[Similar Products]
 NCBI Protein Information    Meckelin; meckel syndrome type 3 protein homolog
 UniProt Protein Name    Meckelin
 UniProt Synonym Protein Names   
Meckel syndrome type 3 protein homolog; Transmembrane protein 67
 Protein Family    Meckelin
 UniProt Gene Name    Tmem67 [Similar Products]
 UniProt Synonym Gene Names    Mks3 [Similar Products]
 UniProt Entry Name    MKS3_MOUSE
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 UniProt Comments for TMEM67    TMEM67: a protein localizes to the primary cilium and to the plasma membrane. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. Essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (SFTPC). Ciliary dysfunction leads to a broad spectrum of disorders, collectively termed ciliopathies. Defects in this protein are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6). Overlapping clinical features include retinal degeneration, renal cystic disease, skeletal abnormalities, fibrosis of various organ, and a complex range of anatomical and functional defects of the central and peripheral nervous system. Interacts with DNAJB9, DNAJC10, MKS1 and mutated SFTPC. Interacts with SYNE2 during the early establishment of cell polarity.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Cellular Component: centrosome; endoplasmic reticulum membrane; cytoskeleton; cell projection; cytoplasmic vesicle membrane; membrane; endoplasmic reticulum; cytoplasm; plasma membrane; integral to membrane; cilium

Molecular Function: unfolded protein binding; filamin binding

Biological Process: ER-associated protein catabolic process; cell projection organization and biogenesis; branching morphogenesis of a tube; cilium biogenesis

Disease: Bardet-biedl Syndrome 1
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 Research Articles on TMEM67    1. TMEM67 mutations cause PKD through ERK- and JNK-dependent signalling pathways, which may provide novel insight into the therapy of polycystic kidney diseases.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TMEM67 elisa kitDiseases associated with TMEM67 elisa kit
 Reference Product  PubMed Publications
 Cep290 elisa kit  >18 publications with TMEM67 and Cep290
 Mks1 elisa kit  >17 publications with TMEM67 and Mks1
 Cc2d2a elisa kit  >15 publications with TMEM67 and Cc2d2a
 Ahi1 elisa kit  >9 publications with TMEM67 and Ahi1
 Tmem216 elisa kit  >6 publications with TMEM67 and Tmem216
 B9d1 elisa kit  >3 publications with TMEM67 and B9d1
 Tctn1 elisa kit  >2 publications with TMEM67 and Tctn1
 Tctn2 elisa kit  >2 publications with TMEM67 and Tctn2
 B9d2 elisa kit  >1 publications with TMEM67 and B9d2
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >24 publications with TMEM67 and Kidney Diseases
 Kidney Diseases, Cystic Antibodies  >23 publications with TMEM67 and Kidney Diseases, Cystic
 Nervous System Malformations Antibodies  >15 publications with TMEM67 and Nervous System Malformations
 Liver Diseases Antibodies  >10 publications with TMEM67 and Liver Diseases
 Fibrosis Antibodies  >8 publications with TMEM67 and Fibrosis
 Meckel syndrome type 3 Antibodies  >3 publications with TMEM67 and Meckel syndrome type 3
 Liver Cirrhosis Antibodies  >3 publications with TMEM67 and Liver Cirrhosis
 Cognition Disorders Antibodies  >2 publications with TMEM67 and Cognition Disorders
 NEPHRONOPHTHISIS 11 Antibodies  >2 publications with TMEM67 and NEPHRONOPHTHISIS 11
 COACH syndrome Antibodies  >2 publications with TMEM67 and COACH syndrome
Organs/Tissues associated with TMEM67 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >16 publications with TMEM67 and Liver
 Brain Antibodies  >11 publications with TMEM67 and Brain
 Eye Antibodies  >8 publications with TMEM67 and Eye
 Molar Antibodies  >6 publications with TMEM67 and Molar
 Embryonic Tissue Antibodies  >1 publications with TMEM67 and Embryonic Tissue
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