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TPM1 elisa kit :: Mouse tropomyosin 1 (alpha) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9325448 TPM1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

tropomyosin 1 (alpha) (TPM1), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Tropomyosin alpha-1 chain, TPM1 ELISA Kit

 Product Synonym Names    Mouse Tropomyosin alpha-1 chain (TPM1) ELISA kit; C15orf13; CMD1Y; HTM-alpha; TMSA; alpha tropomyosin; cardiomyopathy; hypertrophic 3; sarcomeric tropomyosin kappa; tropomyosin 1 alpha chain; tropomyosin 1 (alpha)
 Product Gene Name   

TPM1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P58771
 Species Reactivity    Mouse
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Sandwich (Quantitative)
 Detection Range    0.625 ng/ml - 20 ng/ml.
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TPM1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TPM1 purchase    MBS9325448 is a ready-to-use microwell, strip plate Sandwich (Quantitative) ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the tropomyosin 1 (alpha) (TPM1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625 ng/ml - 20 ng/ml in biological research samples containing TPM1, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9325448 kit is based on TPM1 antibody-TPM1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TPM1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TPM1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for TPM1 elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TPM1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9325448. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TPM1. It may not necessarily be applicable to this product.
 NCBI GI #    256000780
 NCBI GeneID    22003
 NCBI Accession #    NP_001157720.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001164248.1 [Other Products]
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 UniProt Primary Accession #    P58771 [Other Products]
 UniProt Secondary Accession #    P02558; P19354; P46902; P99034 [Other Products]
 UniProt Related Accession #    P58771 [Other Products]
 Molecular Weight    32,681 Da
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 NCBI Official Full Name    tropomyosin alpha-1 chain isoform 1
 NCBI Official Synonym Full Names    tropomyosin 1, alpha
 NCBI Official Symbol    Tpm1 [Similar Products]
 NCBI Official Synonym Symbols   
TM2; Tm3; Tmpa; Tpm-1; AA986836; AI854628; alpha-TM
[Similar Products]
 NCBI Protein Information    tropomyosin alpha-1 chain; tropomyosin-1; alpha tropomyosin; alpha-tropomyosin
 UniProt Protein Name    Tropomyosin alpha-1 chain
 UniProt Synonym Protein Names   
Alpha-tropomyosin; Tropomyosin-1
 Protein Family    Tropomyosin
 UniProt Gene Name    Tpm1 [Similar Products]
 UniProt Synonym Gene Names    Tpm-1; Tpma [Similar Products]
 UniProt Entry Name    TPM1_MOUSE
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 UniProt Comments for TPM1    TPM1: a cytoskeletal protein that binds to actin filaments in muscle and nonmuscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Defects in TPM3 are a cause of nemaline myopathy type 1 (NEM1). Three alternatively spliced isoforms have been described.

Protein type: Actin-binding; Motility/polarity/chemotaxis; Motor

Cellular Component: filamentous actin; protein complex; cytoskeleton; myofibril; cytoplasm; muscle thin filament tropomyosin

Molecular Function: actin filament binding; protein homodimerization activity; structural constituent of cytoskeleton; protein N-terminus binding; actin binding

Biological Process: positive regulation of cell adhesion; wound healing; actin filament capping; in utero embryonic development; muscle filament sliding; regulation of ATPase activity; embryonic development; positive regulation of ATPase activity; positive regulation of stress fiber formation; ruffle organization and biogenesis; ventricular cardiac muscle morphogenesis; negative regulation of cell migration; positive regulation of heart rate by epinephrine; cardiac muscle contraction
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 Research Articles on TPM1    1. This is the first study to demonstrate that decreasing phosphorylation of tropomyosin can rescue a hypertrophic cardiomyopathic phenotype.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with TPM1 elisa kitDiseases associated with TPM1 elisa kit
 Products by Pathway  Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Hypertrophic Cardiomyopathy (HCM) Pathway antibodies  Hypertrophic Cardiomyopathy (HCM) Pathway Diagram
 Hypertrophic Cardiomyopathy (HCM) Pathway antibodies  Hypertrophic Cardiomyopathy (HCM) Pathway Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >56 publications with TPM1 and Cardiovascular Diseases
 Heart Diseases Antibodies  >54 publications with TPM1 and Heart Diseases
 Cardiomyopathies Antibodies  >53 publications with TPM1 and Cardiomyopathies
 Neoplasms Antibodies  >35 publications with TPM1 and Neoplasms
 Cardiomyopathy, Hypertrophic, Familial Antibodies  >22 publications with TPM1 and Cardiomyopathy, Hypertrophic, Familial
 Cardiomegaly Antibodies  >20 publications with TPM1 and Cardiomegaly
 Hypertrophy Antibodies  >19 publications with TPM1 and Hypertrophy
 Heart Failure Antibodies  >17 publications with TPM1 and Heart Failure
 Cardiomyopathy, Dilated Antibodies  >17 publications with TPM1 and Cardiomyopathy, Dilated
 Breast Neoplasms Antibodies  >15 publications with TPM1 and Breast Neoplasms
Organs/Tissues associated with TPM1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >74 publications with TPM1 and Muscle
 Heart Antibodies  >44 publications with TPM1 and Heart
 Embryonic Tissue Antibodies  >7 publications with TPM1 and Embryonic Tissue
 Lung Antibodies  >6 publications with TPM1 and Lung
 Kidney Antibodies  >4 publications with TPM1 and Kidney
 Liver Antibodies  >4 publications with TPM1 and Liver
 Bone Antibodies  >4 publications with TPM1 and Bone
 Skin Antibodies  >4 publications with TPM1 and Skin
 Brain Antibodies  >3 publications with TPM1 and Brain
 Prostate Antibodies  >3 publications with TPM1 and Prostate
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