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UNC13A elisa kit :: Mouse unc-13 homolog A (C. elegans) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9319157 UNC13A elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

unc-13 homolog A (C. elegans) (UNC13A), ELISA Kit

 Also Known As   

Mouse Protein unc-13 homolog A, UNC13A ELISA Kit

 Product Synonym Names    Mouse Protein unc-13 homolog A (UNC13A) ELISA kit; KIAA1032; Munc13-1; unc-13 homolog A; unc-13 homolog A (C. elegans)
 Product Gene Name   

UNC13A elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 3D Structure    ModBase 3D Structure for Q4KUS2
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of UNC13A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for UNC13A purchase    MBS9319157 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the unc-13 homolog A (C. elegans) (UNC13A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing UNC13A. The ELISA analytical biochemical technique of the MBS9319157 kit is based on UNC13A antibody-UNC13A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect UNC13A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, UNC13A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for UNC13A. It may not necessarily be applicable to this product.
 NCBI GI #    283837783
 NCBI GeneID    382018
 NCBI Accession #    NP_001025044.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001029873.2 [Other Products]
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 UniProt Primary Accession #    Q4KUS2 [Other Products]
 UniProt Secondary Accession #    Q3UHG2; E9QKH9 [Other Products]
 UniProt Related Accession #    Q4KUS2 [Other Products]
 Molecular Weight    193,782 Da
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 NCBI Official Full Name    protein unc-13 homolog A
 NCBI Official Synonym Full Names    unc-13 homolog A (C. elegans)
 NCBI Official Symbol    Unc13a [Similar Products]
 NCBI Official Synonym Symbols   
Munc13-1; 2410078G03Rik
[Similar Products]
 NCBI Protein Information    protein unc-13 homolog A
 UniProt Protein Name    Protein unc-13 homolog A
 UniProt Synonym Protein Names   
Munc13-1
 Protein Family    Protein
 UniProt Gene Name    Unc13a [Similar Products]
 UniProt Entry Name    UN13A_MOUSE
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 UniProt Comments for UNC13A    UNC13A: involved in secretory granule priming in insulin secretion and vesicle maturation during exocytosis. A target of the diacylglycerol second messenger pathway. Involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. Interacts with RIMS1, BSN, DOC2A, and STX1A or STX1B1. Localized to the active zone of presynaptic density. Translocated to the plasma membrane as response to phorbol ester.

Protein type: Membrane protein, peripheral

Cellular Component: presynaptic membrane; neuron projection; protein complex; membrane; axon; cytoplasm; plasma membrane; terminal button; excitatory synapse; synapse; cell junction; neuromuscular junction

Molecular Function: diacylglycerol binding; protein domain specific binding; protein binding; SNARE binding; protein homodimerization activity; protein heterodimerization activity; metal ion binding; syntaxin-1 binding; protein N-terminus binding

Biological Process: synaptic transmission; synaptic transmission, glutamatergic; exocytosis; synaptic vesicle maturation; beta-amyloid metabolic process; neurotransmitter secretion; regulation of short-term neuronal synaptic plasticity; synaptic vesicle priming; positive regulation of neurotransmitter secretion; neuromuscular junction development; synaptic vesicle docking during exocytosis
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 Research Articles on UNC13A    1. CAPS1 binds to the full-length of cytoplasmic syntaxin-1 with preference to its "open" conformation, whereas Munc13-1 binds to the first 80 N-terminal residues of syntaxin-1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with UNC13A elisa kitDiseases associated with UNC13A elisa kit
 Products by Pathway  Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram
 Disease Name  Pubmed Publications
 Metabolic Diseases Antibodies  >5 publications with UNC13A and Metabolic Diseases
 Amyotrophic Lateral Sclerosis Antibodies  >4 publications with UNC13A and Amyotrophic Lateral Sclerosis
 Nervous System Diseases Antibodies  >3 publications with UNC13A and Nervous System Diseases
 Hyperglycemia Antibodies  >1 publications with UNC13A and Hyperglycemia
 Dementia Antibodies  >1 publications with UNC13A and Dementia
 Necrosis Antibodies  >1 publications with UNC13A and Necrosis
Organs/Tissues associated with UNC13A elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >11 publications with UNC13A and Brain
 Pancreas Antibodies  >5 publications with UNC13A and Pancreas
 Spinal Cord Antibodies  >1 publications with UNC13A and Spinal Cord
 Skin Antibodies  >1 publications with UNC13A and Skin
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