P25976.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
89,509 Da
NCBI Official Full Name
Nucleolar transcription factor 1
NCBI Official Synonym Full Names
upstream binding transcription factor, RNA polymerase I
NCBI Official Synonym Symbols
UBF; UBF1; NOR-90; Tcfubf; A930005G04Rik [Similar Products]
NCBI Protein Information
nucleolar transcription factor 1; UBF-1; transcription factor UBF; upstream-binding factor 1
UniProt Protein Name
Nucleolar transcription factor 1
UniProt Synonym Protein Names
Upstream-binding factor 1; UBF-1
UniProt Synonym Gene Names
UniProt Entry Name
UBF1_MOUSE
UniProt Comments for UBTF
UBF: a transcription factor that recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the species-specific factor SL1. Activate RNA polymerase II-regulated, beta-catenin-responsive promoters. Interacts with TAF1, a factor involved in the transcription of cell cycle and growth regulatory genes. It binds specifically to the upstream control element. Two splice variant isoforms have been described.
Protein type: DNA-binding; Nucleolus; Transcription factor
Cellular Component: fibrillar center; nucleolus; nucleus
Molecular Function: protein binding; DNA binding; chromatin binding
Biological Process: chromatin silencing at rDNA; chromatin remodeling; regulation of transcription, DNA-dependent; transcription, DNA-dependent; RNA elongation from RNA polymerase I promoter; positive regulation of transcription from RNA polymerase I promoter
Research Articles on UBTF
Precautions
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Disclaimer
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Pathways associated with UBTF elisa kit
Organs/Tissues associated with UBTF elisa kit
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