Q4JIM5.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
128,196 Da
NCBI Official Full Name
Abelson tyrosine-protein kinase 2
NCBI Official Synonym Full Names
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
NCBI Protein Information
Abelson tyrosine-protein kinase 2; tyrosine kinase ARG; tyrosine-protein kinase ARG; Abelson-related gene protein; tyrosine-protein kinase ABL2; abelson murine leukemia viral oncogene homolog 2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)
UniProt Protein Name
Abelson tyrosine-protein kinase 2
UniProt Synonym Protein Names
Abelson murine leukemia viral oncogene homolog 2; Abelson-related gene protein; Tyrosine-protein kinase ARG
UniProt Synonym Gene Names
UniProt Entry Name
ABL2_MOUSE
UniProt Comments for ABL2
Arg: a cytoplasmic tyrosine kinase of the Abl family. Expressed at the highest levels in mature B cells. Promotes catalase degradation in the oxidative stress response. Localizes to dynamic actin structures and may regulate cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, TK; Oncoprotein; Protein kinase, tyrosine (non-receptor); EC 2.7.10.2; Kinase, protein; TK group; Abl family
Cellular Component: extrinsic to internal side of plasma membrane; cytoskeleton; cell; lamellipodium; cytoplasm; cytoplasmic membrane-bound vesicle; dendritic spine; cytosol; actin cytoskeleton; phagocytic cup
Molecular Function: transferase activity; protein binding; manganese ion binding; metal ion binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; magnesium ion binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; kinase activity; ATP binding; receptor binding; protein kinase activity
Biological Process: peptidyl-tyrosine phosphorylation; positive regulation of protein binding; cerebellum morphogenesis; alpha-beta T cell differentiation; platelet-derived growth factor receptor signaling pathway; protein amino acid phosphorylation; regulation of apoptosis; Bergmann glial cell differentiation; elevation of cytosolic calcium ion concentration; visual learning; cell adhesion; neuromuscular process controlling balance; positive regulation of oxidoreductase activity; epidermal growth factor receptor signaling pathway; actin filament bundle formation; cell migration; positive regulation of I-kappaB kinase/NF-kappaB cascade; dendrite morphogenesis; actin filament organization; learning; substrate-bound cell migration, cell extension; phagocytosis; regulation of cell proliferation; negative regulation of Rho protein signal transduction; innate immune response; negative regulation of cell-cell adhesion; actin cytoskeleton organization and biogenesis; phosphorylation; neuron remodeling
Research Articles on ABL2
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Pathways associated with ABL2 elisa kit
Organs/Tissues associated with ABL2 elisa kit
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