NP_035848.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
43,119 Da
NCBI Official Full Name
protein Wnt-10b
NCBI Official Synonym Full Names
wingless-type MMTV integration site family, member 10B
NCBI Official Synonym Symbols
NCBI Protein Information
protein Wnt-10b; wnt-12; wingless related MMTV integration site 10b
UniProt Protein Name
Protein Wnt-10b
UniProt Synonym Protein Names
Protein Wnt-12
UniProt Synonym Gene Names
UniProt Entry Name
WN10B_MOUSE
UniProt Comments for WNT10B
WNT10B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Defects in WNT10B are the cause of split-hand/foot malformation type 6 (SHFM6). SHFM is a limb malformation involving the central rays of the autopod and presenting with syndactyly, median clefts of the hands and feet, and aplasia and/or hypoplasia of the phalanges, metacarpals, and metatarsals. SHFM6 is a autosomal recessive disorder. Belongs to the Wnt family.
Protein type: Secreted; Secreted, signal peptide
Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region
Molecular Function: frizzled binding; receptor binding
Biological Process: regulation of fat cell differentiation; positive regulation of apoptosis; multicellular organismal development; regulation of protein metabolic process; skeletal muscle fiber development; Wnt receptor signaling pathway through beta-catenin; negative regulation of transcription from RNA polymerase II promoter; signal transduction; neuron differentiation; cell-cell signaling; positive regulation of cell proliferation; positive regulation of epithelial cell differentiation; G2/M transition of mitotic cell cycle; positive regulation of transcriptional preinitiation complex assembly; cell cycle arrest; negative regulation of epithelial cell proliferation; smoothened signaling pathway; Wnt receptor signaling pathway; cell fate commitment; sensory perception of taste; protein stabilization; regulation of proteasomal ubiquitin-dependent protein catabolic process; skeletal muscle regeneration; negative regulation of fat cell differentiation; positive regulation of bone mineralization; positive regulation of ossification; regulation of transcription from RNA polymerase II promoter; positive regulation of osteoblast differentiation; organ morphogenesis; regulation of skeletal muscle development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; lipid metabolic process; positive regulation of anagen; myoblast cell differentiation involved in skeletal muscle regeneration
Research Articles on WNT10B
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with WNT10B elisa kit
Diseases associated with WNT10B elisa kit
Organs/Tissues associated with WNT10B elisa kit
|