NP_766142.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
72,621 Da
NCBI Official Full Name
palmitoyltransferase ZDHHC17
NCBI Official Synonym Full Names
zinc finger, DHHC domain containing 17
NCBI Official Synonym Symbols
Hip14; BB187739; A230053P19Rik; D130071N24Rik [Similar Products]
NCBI Protein Information
palmitoyltransferase ZDHHC17; DHHC-17; huntingtin interacting protein 14; huntingtin-interacting protein 14; zinc finger DHHC domain-containing protein 17
UniProt Protein Name
Palmitoyltransferase ZDHHC17
UniProt Synonym Protein Names
Huntingtin-interacting protein 14; Zinc finger DHHC domain-containing protein 17; DHHC-17
UniProt Synonym Gene Names
UniProt Entry Name
ZDH17_MOUSE
UniProt Comments for ZDHHC17
HIP14: a palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, PSD-95, GAD2, SYT1 and Huntingtin. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. May be involved in the NF-kappa-B signaling pathway. Can cause cellular transformation, and is up-regulated in a number of types of human tumors. Expressed in all brain regions. Expression is highest in the cortex, cerebellum, occipital lobe and caudate, and lowest in the spinal cord. Expression is also seen in testis, pancreas, heart and kidney. Three alternatively spliced isoforms have been described.
Protein type: Membrane protein, integral; Tumor suppressor; EC 2.3.1.225; Membrane protein, multi-pass; Transferase
Cellular Component: Golgi membrane; Golgi apparatus; intracellular membrane-bound organelle; membrane; cytoplasm; integral to membrane; cytoplasmic vesicle
Molecular Function: transferase activity; identical protein binding; signal transducer activity; zinc ion binding; metal ion binding; palmitoyltransferase activity; transferase activity, transferring acyl groups; magnesium ion transmembrane transporter activity; protein-cysteine S-palmitoleyltransferase activity
Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; protein palmitoylation; transport; lipoprotein transport; ion transport; signal transduction; magnesium ion transport
Research Articles on ZDHHC17
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Diseases associated with ZDHHC17 elisa kit
Organs/Tissues associated with ZDHHC17 elisa kit
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