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CASP3 elisa kit :: Pig Caspase-3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2880779
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $420 +1 FREE 8GB USB
96-Strip-Wells  /  $560 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,445 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,520 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Caspase-3 (CASP3), ELISA Kit

★Popular Item★
 Also Known As   

Pig Caspase-3 ELISA Kit

 Product Synonym Names    Caspase-3; CASP-3; CASP3; 3.4.22.56
 Product Gene Name   

CASP3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2880779 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for Q95ND5
 Species Reactivity    Pig
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 Samples    Serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CASP3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CASP3 purchase    MBS2880779 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Caspase-3 (CASP3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CASP3. The ELISA analytical biochemical technique of the MBS2880779 kit is based on CASP3 antibody-CASP3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CASP3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CASP3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CASP3 elisa kit

   Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of CASP3 elisa kit    CASP3 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2880779. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CASP3. It may not necessarily be applicable to this product.
 NCBI GI #    47523066
 NCBI GeneID    397244
 NCBI Accession #    NP_999296.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_214131.1 [Other Products]
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 UniProt Primary Accession #    Q95ND5 [Other Products]
 UniProt Related Accession #    Q95ND5 [Other Products]
 Molecular Weight    31,379 Da
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 NCBI Official Full Name    caspase-3
 NCBI Official Symbol    CASP3 [Similar Products]
 NCBI Protein Information    caspase-3
 UniProt Protein Name    Caspase-3
 Protein Family    Caspase
 UniProt Gene Name    CASP3 [Similar Products]
 UniProt Synonym Gene Names    CASP-3 [Similar Products]
 UniProt Entry Name    CASP3_PIG
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 UniProt Comments for CASP3    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage ().
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 Research Articles on CASP3    1. Caspase-3 (CC3) was shown to be more abundant in early-cleaving and more developmentally competent embryos compared to late-cleaving and less developmentally competent embryos.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CASP3 elisa kitPathways associated with CASP3 elisa kit
 Reference Product  PubMed Publications
 XIAP elisa kit  >930 publications with CASP3 and XIAP
 APAF1 elisa kit  >329 publications with CASP3 and APAF1
 GZMB elisa kit  >149 publications with CASP3 and GZMB
 BIRC2 elisa kit  >36 publications with CASP3 and BIRC2
 CDH1 elisa kit  >7 publications with CASP3 and CDH1
 Products by Pathway  Pathway Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 Activation Of DNA Fragmentation Factor Pathway antibodies  Activation Of DNA Fragmentation Factor Pathway Diagram
 Activation Of Caspases Through Apoptosome-mediated Cleavage Pathway antibodies  Activation Of Caspases Through Apoptosome-mediated Cleavage Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
Diseases associated with CASP3 elisa kitOrgans/Tissues associated with CASP3 elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >5996 publications with CASP3 and Necrosis
 Nervous System Diseases Antibodies  >4598 publications with CASP3 and Nervous System Diseases
 Inflammation Antibodies  >3018 publications with CASP3 and Inflammation
 Reperfusion Injury Antibodies  >2014 publications with CASP3 and Reperfusion Injury
 Liver Diseases Antibodies  >1977 publications with CASP3 and Liver Diseases
 Brain Ischemia Antibodies  >1457 publications with CASP3 and Brain Ischemia
 Heart Diseases Antibodies  >1354 publications with CASP3 and Heart Diseases
 Breast Neoplasms Antibodies  >1273 publications with CASP3 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >1152 publications with CASP3 and Neoplasms, Experimental
 Kidney Diseases Antibodies  >758 publications with CASP3 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6769 publications with CASP3 and Blood
 Brain Antibodies  >6769 publications with CASP3 and Brain
 Liver Antibodies  >3654 publications with CASP3 and Liver
 Muscle Antibodies  >3004 publications with CASP3 and Muscle
 Lung Antibodies  >2815 publications with CASP3 and Lung
 Skin Antibodies  >953 publications with CASP3 and Skin
 Intestine Antibodies  >808 publications with CASP3 and Intestine
 Embryonic Tissue Antibodies  >714 publications with CASP3 and Embryonic Tissue
 Ovary Antibodies  >547 publications with CASP3 and Ovary
 Spleen Antibodies  >405 publications with CASP3 and Spleen
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