NP_999165.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
38,482 Da
NCBI Official Full Name
haptoglobin
NCBI Protein Information
haptoglobin
UniProt Protein Name
Haptoglobin
UniProt Synonym Protein Names
Zonulin
UniProt Comments for CLCN5
HP: Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes. Defects in HP are the cause of anhaptoglobinemia (AHP). AHP is a condition characterized by the absence of the serum glycoprotein haptoglobin. Serum levels of haptoglobin vary among normal persons: levels are low in the neonatal period and in the elderly, differ by population, and can be influenced by environmental factors, such as infection. Secondary hypohaptoglobinemia can occur as a consequence of hemolysis, during which haptoglobin binds to free hemoglobin. Belongs to the peptidase S1 family.
Protein type: Endoplasmic reticulum; Secreted; Secreted, signal peptide
Cellular Component: extracellular region
Molecular Function: antioxidant activity; hemoglobin binding
Biological Process: acute-phase response; defense response to bacterium; immune system process
Research Articles on CLCN5
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Products associated with CLCN5 elisa kit
Pathways associated with CLCN5 elisa kit
Diseases associated with CLCN5 elisa kit
Organs/Tissues associated with CLCN5 elisa kit
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