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OGT elisa kit :: Pig O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2602956 OGT elisa kit
Unit / Price
48-Strip-Wells  /  $300 +1 FREE 8GB USB
96-Strip-Wells  /  $475 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) (OGT), ELISA Kit

 Also Known As   

Pig UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, OGT ELISA Kit

 Product Gene Name   

OGT elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q27HV0
 Species Reactivity    Pig
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of OGT elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for OGT purchase    MBS2602956 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) (OGT) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing OGT. The ELISA analytical biochemical technique of the MBS2602956 kit is based on OGT antibody-OGT antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect OGT antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, OGT. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for OGT. It may not necessarily be applicable to this product.
 NCBI GI #    89886173
 NCBI GeneID    664652
 NCBI Accession #    NP_001034837.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001039748.2 [Other Products]
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 UniProt Primary Accession #    Q27HV0 [Other Products]
 UniProt Related Accession #    Q27HV0 [Other Products]
 Molecular Weight    116,923 Da [Similar Products]
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 NCBI Official Full Name    UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
 NCBI Official Symbol    OGT [Similar Products]
 NCBI Protein Information    UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine transferase 110 kDa subunit; O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
 UniProt Protein Name    UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
 UniProt Synonym Protein Names   
O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine transferase 110 kDa subunit; OGT
 Protein Family    Methylated-DNA--protein-cysteine methyltransferase
 UniProt Gene Name    OGT [Similar Products]
 UniProt Synonym Gene Names    OGT [Similar Products]
 UniProt Entry Name    OGT1_PIG
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 UniProt Comments for OGT    Function: Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Glycosylates a large and diverse number of proteins including histone H2B, AKT1, EZH2, PFKL, KMT2E/MLL5, MAPT/TAU and HCFC1. Can regulate their cellular processes via cross-talk between glycosylation and phosphorylation or by affecting proteolytic processing. Involved in insulin resistance in muscle and adipocyte cells via glycosylating insulin signaling components and inhibiting the 'Thr-308' phosphorylation of AKT1, enhancing IRS1 phosphorylation and attenuating insulin signaling. Involved in glycolysis regulation by mediating glycosylation of 6-phosphofructokinase PFKL, inhibiting its activity. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. Plays a key role in chromatin structure by mediating O-GlcNAcylation of 'Ser-112' of histone H2B: recruited to CpG-rich transcription start sites of active genes via its interaction with TET proteins (TET1, TET2 or TET3). As part of the NSL complex indirectly involved in acetylation of nucleosomal histone H4 on several lysine residues. O-GlcNAcylation of 'Ser-75' of EZH2 increases its stability, and facilitating the formation of H3K27me3 by the PRC2/EED-EZH2 complex. Regulates circadian oscillation of the clock genes and glucose homeostasis in the liver. Stabilizes clock proteins ARNTL/BMAL1 and CLOCK through O-glycosylation, which prevents their ubiquitination and subsequent degradation. Promotes the CLOCK-ARNTL/BMAL1-mediated transcription of genes in the negative loop of the circadian clock such as PER1/2 and CRY1/2

Catalytic activity: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with OGT elisa kitDiseases associated with OGT elisa kit
 Products by Pathway  Pathway Diagram
 Other Types Of O-glycan Biosynthesis Pathway antibodies  Other Types Of O-glycan Biosynthesis Pathway Diagram
 Other Types Of O-glycan Biosynthesis Pathway antibodies  Other Types Of O-glycan Biosynthesis Pathway Diagram
 Disease Name  Pubmed Publications
 Drug Toxicity Antibodies  >33 publications with OGT and Drug Toxicity
 Neoplasms Antibodies  >23 publications with OGT and Neoplasms
 Cardiovascular Diseases Antibodies  >20 publications with OGT and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >18 publications with OGT and Nervous System Diseases
 Brain Diseases Antibodies  >14 publications with OGT and Brain Diseases
 Disease Models, Animal Antibodies  >11 publications with OGT and Disease Models, Animal
 Heart Diseases Antibodies  >9 publications with OGT and Heart Diseases
 Liver Diseases Antibodies  >9 publications with OGT and Liver Diseases
 Stomach Diseases Antibodies  >8 publications with OGT and Stomach Diseases
 Mental Disorders Antibodies  >7 publications with OGT and Mental Disorders
Organs/Tissues associated with OGT elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >56 publications with OGT and Blood
 Liver Antibodies  >31 publications with OGT and Liver
 Muscle Antibodies  >18 publications with OGT and Muscle
 Brain Antibodies  >16 publications with OGT and Brain
 Stomach Antibodies  >11 publications with OGT and Stomach
 Kidney Antibodies  >10 publications with OGT and Kidney
 Spleen Antibodies  >8 publications with OGT and Spleen
 Lung Antibodies  >7 publications with OGT and Lung
 Skin Antibodies  >5 publications with OGT and Skin
 Intestine Antibodies  >5 publications with OGT and Intestine
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