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FGF19 elisa kit :: Pig fibroblast growth factor 19 (FGF19) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS906452
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $550 +1 FREE 8GB USB
96-Strip-Wells  /  $795 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,890 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,465 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

fibroblast growth factor 19 (FGF19), ELISA Kit

★Popular Item★
 Also Known As   

Pig fibroblast growth factor 19, FGF19 ELISA Kit

 Product Synonym Names    Pig fibroblast growth factor 19 (FGF19) ELISA Kit; fibroblast growth factor 19 (FGF19)
 Product Gene Name   

FGF19 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS906452 Testing Data    Testing Data PDF
 OMIM    603891
 3D Structure    ModBase 3D Structure for O95750
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 Species Reactivity    Pig
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 Specificity    This assay has high sensitivity and excellent specificity for detection of pig FGF19. No significant cross-reactivity or interference between pig FGF19 and analogues was observed.
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 Samples    Serum, plasma
 Assay Type    Sandwich
 Detection Range    15.6 pg/ml -1000 pg/ml.
 Sensitivity    The minimum detectable dose of pig FGF19 is typically less than 3.9 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FGF19 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FGF19 purchase    MBS906452 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the fibroblast growth factor 19 (FGF19) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.6 pg/ml -1000 pg/ml in biological research samples containing FGF19, with an estimated sensitivity of The minimum detectable dose of pig FGF19 is typically less than 3.9 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. The ELISA analytical biochemical technique of the MBS906452 kit is based on FGF19 antibody-FGF19 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FGF19 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FGF19. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for FGF19 elisa kit

   Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for FGF19 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any FGF19 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FGF19 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FGF19 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of FGF19 elisa kit    FGF19 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS906452. Click to request current manual
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NCBI/Uniprot data below describe general gene information for FGF19. It may not necessarily be applicable to this product.
 NCBI GI #    4826726
 NCBI GeneID    9965
 NCBI Accession #    NP_005108.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005117.2 [Other Products]
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 UniProt Primary Accession #    O95750 [Other Products]
 UniProt Related Accession #    O95750 [Other Products]
 Molecular Weight    24,003 Da
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 NCBI Official Full Name    fibroblast growth factor 19
 NCBI Official Synonym Full Names    fibroblast growth factor 19
 NCBI Official Symbol    FGF19 [Similar Products]
 NCBI Protein Information    fibroblast growth factor 19; FGF-19
 UniProt Protein Name    Fibroblast growth factor 19
 Protein Family    Fibroblast growth factor
 UniProt Gene Name    FGF19 [Similar Products]
 UniProt Synonym Gene Names    UNQ334/PRO533; FGF-19 [Similar Products]
 UniProt Entry Name    FGF19_HUMAN
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 NCBI Summary for FGF19    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FGF19    FGF19: Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. Belongs to the heparin-binding growth factors family.

Protein type: Secreted, signal peptide; Cytokine; Cell development/differentiation; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: extracellular region

Molecular Function: protein binding; growth factor activity; fibroblast growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; positive regulation of glucose import; nervous system development; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; heart development; positive regulation of cell proliferation; insulin receptor signaling pathway; positive regulation of JNK cascade; innate immune response; positive regulation of protein amino acid phosphorylation; neural crest cell migration
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 Research Articles on FGF19    1. [review] While FGF19 is a negative feedback regulator of bile acid metabolism and can circulate as a hormone, emerging evidence has showed its autocrine or exocrine function.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FGF19 elisa kitPathways associated with FGF19 elisa kit
 Reference Product  PubMed Publications
 FGFR4 elisa kit  >45 publications with FGF19 and FGFR4
 Products by Pathway  Pathway Diagram
 Downstream Signaling Of Activated FGFR Pathway antibodies  Downstream Signaling Of Activated FGFR Pathway Diagram
 FGF Signaling Pathway antibodies  FGF Signaling Pathway Diagram
 FGFR Ligand Binding And Activation Pathway antibodies  FGFR Ligand Binding And Activation Pathway Diagram
 FGFR4 Ligand Binding And Activation Pathway antibodies  FGFR4 Ligand Binding And Activation Pathway Diagram
 FRS2-mediated Cascade Pathway antibodies  FRS2-mediated Cascade Pathway Diagram
 IRS-mediated Signalling Pathway antibodies  IRS-mediated Signalling Pathway Diagram
 IRS-related Events Pathway antibodies  IRS-related Events Pathway Diagram
 Insulin Receptor Signalling Cascade Pathway antibodies  Insulin Receptor Signalling Cascade Pathway Diagram
 Klotho-mediated Ligand Binding Pathway antibodies  Klotho-mediated Ligand Binding Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
Diseases associated with FGF19 elisa kitOrgans/Tissues associated with FGF19 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >33 publications with FGF19 and Neoplasms
 Liver Diseases Antibodies  >17 publications with FGF19 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >12 publications with FGF19 and Carcinoma, Hepatocellular
 Diarrhea Antibodies  >11 publications with FGF19 and Diarrhea
 Skin Diseases Antibodies  >5 publications with FGF19 and Skin Diseases
 Gallstones Antibodies  >4 publications with FGF19 and Gallstones
 Cholestasis Antibodies  >3 publications with FGF19 and Cholestasis
 Inflammation Antibodies  >3 publications with FGF19 and Inflammation
 Heart Diseases Antibodies  >1 publications with FGF19 and Heart Diseases
 Abdominal Pain Antibodies  >1 publications with FGF19 and Abdominal Pain
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >21 publications with FGF19 and Intestine
 Brain Antibodies  >10 publications with FGF19 and Brain
 Embryonic Tissue Antibodies  >9 publications with FGF19 and Embryonic Tissue
 Parathyroid Antibodies  >3 publications with FGF19 and Parathyroid
 Uterus Antibodies  >1 publications with FGF19 and Uterus
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