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IGFBP3 elisa kit :: Pig insulin-like growth factor binding protein 3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS703351
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $450 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,615 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,940 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

insulin-like growth factor binding protein 3 (IGFBP3), ELISA Kit

★Popular Item★
 Also Known As   

Pig insulin-like growth factors binding protein 3, IGFBP-3 ELISA Kit

 Product Synonym Names    Pig insulin-like growth factors binding protein 3; IGFBP-3 ELISA Kit; tcag7.703; BP-53; IBP3; IGF-binding protein 3; acid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; growth hormone-dependent binding protein; insulin-like growth factor binding protein 3
 Product Gene Name   

IGFBP3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS703351 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for P16611
 Species Reactivity    Pig
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 Specificity    This assay has high sensitivity and excellent specificity for detection of pig IGFBP-3. No significant cross-reactivity or interference between pig IGFBP-3 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates.
 Assay Type    Sandwich
 Detection Range    78 ng/ml -5000 ng/ml.
 Sensitivity    19.5 ng/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IGFBP3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IGFBP3 purchase    MBS703351 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the insulin-like growth factor binding protein 3 (IGFBP3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78 ng/ml -5000 ng/ml in biological research samples containing IGFBP3, with an estimated sensitivity of 19.5 ng/ml. The ELISA analytical biochemical technique of the MBS703351 kit is based on IGFBP3 antibody-IGFBP3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IGFBP3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IGFBP3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IGFBP3 elisa kit

   Principle of the Assay||This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IGFBP-3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IGFBP-3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IGFBP-3 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IGFBP-3 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of IGFBP3 elisa kit    IGFBP3 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS703351. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IGFBP3. It may not necessarily be applicable to this product.
 NCBI GI #    52346224
 NCBI GeneID    448812
 NCBI Accession #    NP_001005156.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001005156.1 [Other Products]
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 UniProt Primary Accession #    P16611 [Other Products]
 UniProt Secondary Accession #    Q6S6K2; Q9TTI0 [Other Products]
 UniProt Related Accession #    P16611 [Other Products]
 Molecular Weight    31,690 Da
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 NCBI Official Full Name    insulin-like growth factor-binding protein 3
 NCBI Official Symbol    IGFBP3 [Similar Products]
 NCBI Official Synonym Symbols   
IGFBP-3
[Similar Products]
 NCBI Protein Information    insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3
 UniProt Protein Name    Insulin-like growth factor-binding protein 3
 Protein Family    Insulin-like growth factor-binding protein
 UniProt Gene Name    IGFBP3 [Similar Products]
 UniProt Synonym Gene Names    IBP-3; IGF-binding protein 3; IGFBP-3 [Similar Products]
 UniProt Entry Name    IBP3_PIG
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 UniProt Comments for IGFBP3    Function: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
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 Research Articles on IGFBP3    1. IGF-I, IGF-II, and IGFBP-3 mRNA were positively correlated with IGF-IR from 50E to 180D, suggesting that the expression of IGF-system genes exhibits specific developmental patterns in the skeletal muscle tissues.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with IGFBP3 elisa kitDiseases associated with IGFBP3 elisa kit
 Products by Pathway  Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 P53 Signaling Pathway antibodies  P53 Signaling Pathway Diagram
 P53 Signaling Pathway antibodies  P53 Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >341 publications with IGFBP3 and Breast Neoplasms
 Prostatic Neoplasms Antibodies  >256 publications with IGFBP3 and Prostatic Neoplasms
 Cardiovascular Diseases Antibodies  >220 publications with IGFBP3 and Cardiovascular Diseases
 Adenocarcinoma Antibodies  >172 publications with IGFBP3 and Adenocarcinoma
 Weight Gain Antibodies  >145 publications with IGFBP3 and Weight Gain
 Colorectal Neoplasms Antibodies  >144 publications with IGFBP3 and Colorectal Neoplasms
 Liver Diseases Antibodies  >142 publications with IGFBP3 and Liver Diseases
 Lung Diseases Antibodies  >136 publications with IGFBP3 and Lung Diseases
 Inflammation Antibodies  >127 publications with IGFBP3 and Inflammation
 Kidney Diseases Antibodies  >123 publications with IGFBP3 and Kidney Diseases
Organs/Tissues associated with IGFBP3 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >372 publications with IGFBP3 and Liver
 Muscle Antibodies  >261 publications with IGFBP3 and Muscle
 Connective Tissue Antibodies  >199 publications with IGFBP3 and Connective Tissue
 Kidney Antibodies  >193 publications with IGFBP3 and Kidney
 Brain Antibodies  >174 publications with IGFBP3 and Brain
 Lung Antibodies  >153 publications with IGFBP3 and Lung
 Ovary Antibodies  >151 publications with IGFBP3 and Ovary
 Heart Antibodies  >113 publications with IGFBP3 and Heart
 Placenta Antibodies  >69 publications with IGFBP3 and Placenta
 Embryonic Tissue Antibodies  >69 publications with IGFBP3 and Embryonic Tissue
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