NP_001123683.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
28,726 Da
NCBI Official Full Name
transcription factor A, mitochondrial
NCBI Protein Information
transcription factor A, mitochondrial; mtTFA; mitochondrial transcription factor A
UniProt Protein Name
Transcription factor A, mitochondrial
UniProt Synonym Gene Names
UniProt Entry Name
TFAM_PIG
UniProt Comments for TFAM
Function: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA
Research Articles on TFAM
Precautions
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Disclaimer
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Pathways associated with TFAM elisa kit
Diseases associated with TFAM elisa kit
Organs/Tissues associated with TFAM elisa kit
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