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TP53 elisa kit :: Pig tumor protein p53 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9320131 TP53 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

tumor protein p53 (TP53), ELISA Kit

★Popular Item★
 Also Known As   

Pig Cellular tumor antigen p53, TP53 ELISA Kit

 Product Synonym Names    Pig Cellular tumor antigen p53 (TP53) ELISA kit; FLJ92943; LFS1; TRP53; p53; p53 antigen; p53 transformation suppressor; p53 tumor suppressor; phosphoprotein p53; transformation-related protein 53; tumor protein p53
 Product Gene Name   

TP53 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q9TUB2
 Species Reactivity    Pig
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Quantitative Sandwich
 Detection Range    62.5 pg/ml - 2000 pg/ml.
 Sensitivity    10 pg/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TP53 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TP53 purchase    MBS9320131 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the tumor protein p53 (TP53) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5 pg/ml - 2000 pg/ml in biological research samples containing TP53, with an estimated sensitivity of 10 pg/ml. The ELISA analytical biochemical technique of the MBS9320131 kit is based on TP53 antibody-TP53 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TP53 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TP53. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for TP53 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TP53 (hereafter termed "analyte") in undiluted original Porcine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9320131. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TP53. It may not necessarily be applicable to this product.
 NCBI GI #    325651918
 NCBI GeneID    397276
 NCBI Accession #    NP_998989.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_213824.3 [Other Products]
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 UniProt Primary Accession #    Q9TUB2 [Other Products]
 UniProt Related Accession #    Q9TUB2 [Other Products]
 Molecular Weight    42,862 Da
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 NCBI Official Full Name    cellular tumor antigen p53
 NCBI Official Symbol    TP53 [Similar Products]
 NCBI Official Synonym Symbols   
P53
[Similar Products]
 NCBI Protein Information    cellular tumor antigen p53; tumor suppressor p53
 UniProt Protein Name    Cellular tumor antigen p53
 UniProt Synonym Protein Names   
Tumor suppressor p53
 Protein Family    Tumor protein p53-inducible protein
 UniProt Gene Name    TP53 [Similar Products]
 UniProt Synonym Gene Names    P53 [Similar Products]
 UniProt Entry Name    P53_PIG
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 UniProt Comments for TP53    Function: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation

Cofactor: Binds 1 zinc ion per subunit
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 Research Articles on TP53    1. Data indicate that higher hepatic glucocorticoid receptor (GR) expression in EHL piglets attributes mainly to the enhanced transcription of GR promoter 1-9/10 from breed-specific interaction of p53 and specificity protein 1 (Sp1).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with TP53 elisa kitOrgans/Tissues associated with TP53 elisa kit
 Disease Name  Pubmed Publications
 Li-Fraumeni Syndrome Antibodies  >2500 publications with TP53 and Li-Fraumeni Syndrome
 Adenocarcinoma Antibodies  >810 publications with TP53 and Adenocarcinoma
 Breast Neoplasms Antibodies  >733 publications with TP53 and Breast Neoplasms
 Carcinoma, Squamous Cell Antibodies  >453 publications with TP53 and Carcinoma, Squamous Cell
 Lung Neoplasms Antibodies  >420 publications with TP53 and Lung Neoplasms
 Carcinoma, Small Cell Antibodies  >275 publications with TP53 and Carcinoma, Small Cell
 Neoplasm Metastasis Antibodies  >240 publications with TP53 and Neoplasm Metastasis
 Sarcoma Antibodies  >226 publications with TP53 and Sarcoma
 Urinary Bladder Neoplasms Antibodies  >198 publications with TP53 and Urinary Bladder Neoplasms
 Liver Neoplasms Antibodies  >189 publications with TP53 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >495 publications with TP53 and Lung
 Skin Antibodies  >218 publications with TP53 and Skin
 Lymph Antibodies  >193 publications with TP53 and Lymph
 Kidney Antibodies  >84 publications with TP53 and Kidney
 Intestine Antibodies  >65 publications with TP53 and Intestine
 Embryonic Tissue Antibodies  >29 publications with TP53 and Embryonic Tissue
 Adrenal Gland Antibodies  >15 publications with TP53 and Adrenal Gland
 Thymus Antibodies  >10 publications with TP53 and Thymus
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