NP_001072141.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
16,737 Da
NCBI Official Full Name
ubiquitin-conjugating enzyme E2 D2
NCBI Protein Information
ubiquitin-conjugating enzyme E2 D2; UB2D2; ubiquitin-protein ligase D2; ubiquitin carrier protein D2; ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
UniProt Protein Name
Ubiquitin-conjugating enzyme E2 D2
UniProt Synonym Protein Names
Ubiquitin carrier protein D2; Ubiquitin-protein ligase D2
UniProt Synonym Gene Names
UniProt Entry Name
UB2D2_PIG
UniProt Comments for UBE2D2
Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3
Catalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
Research Articles on UBE2D2
Precautions
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Products associated with UBE2D2 elisa kit
Pathways associated with UBE2D2 elisa kit
Diseases associated with UBE2D2 elisa kit
Organs/Tissues associated with UBE2D2 elisa kit
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