NP_071565.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
60,955 Da
NCBI Official Full Name
60 kDa heat shock protein, mitochondrial
NCBI Official Synonym Full Names
heat shock protein 1 (chaperonin)
NCBI Protein Information
60 kDa heat shock protein, mitochondrial; CPN60; HSP-60; HSP-65; chaperonin 60; 60 kDa chaperonin; heat shock 60kDa protein 1; heat shock protein 60 (liver); mitochondrial matrix protein P1; heat shock 60kD protein 1 (chaperonin)
UniProt Protein Name
60 kDa heat shock protein, mitochondrial
UniProt Synonym Protein Names
60 kDa chaperonin; Chaperonin 60; CPN60; HSP-65; Heat shock protein 60; HSP-60; Hsp60; Mitochondrial matrix protein P1
UniProt Synonym Gene Names
UniProt Entry Name
CH60_RAT
NCBI Summary for 6-OHDA
a stress-inducible molecular chaperone which participates in protein folding [RGD, Feb 2006]
UniProt Comments for 6-OHDA
HSP60: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. Interacts with HRAS. Interacts with HBV protein X and HTLV-1 protein p40tax. Belongs to the chaperonin (HSP60) family.
Protein type: Chaperone; Mitochondrial
Cellular Component: Golgi apparatus; extracellular space; protein complex; cell surface; intracellular membrane-bound organelle; rough endoplasmic reticulum; mitochondrion; early endosome; coated pit; cytosol; lipid raft; secretory granule; mitochondrial crista; membrane; mitochondrial matrix; cytoplasm; mitochondrial inner membrane; plasma membrane; lipopolysaccharide receptor complex; myelin sheath; cyclin-dependent protein kinase activating kinase holoenzyme complex
Molecular Function: insulin binding; protein binding; protease binding; protein heterodimerization activity; lipopolysaccharide binding; p53 binding; ubiquitin protein ligase binding; chaperone binding; double-stranded RNA binding; protein complex binding; misfolded protein binding; ATP binding
Biological Process: B cell proliferation; T cell activation; positive regulation of apoptosis; positive regulation of interleukin-12 production; isotype switching to IgG isotypes; response to lipopolysaccharide; response to organic cyclic substance; positive regulation of interleukin-10 production; response to organic substance; protein refolding; positive regulation of T cell mediated immune response to tumor cell; negative regulation of neuron apoptosis; positive regulation of interferon-alpha production; positive regulation of macrophage activation; caspase activation; response to drug; B cell activation; chaperone cofactor-dependent protein folding; protein stabilization; positive regulation of interleukin-6 production; B cell cytokine production; detection of misfolded protein; response to cocaine; response to unfolded protein; response to ATP; MyD88-dependent toll-like receptor signaling pathway; positive regulation of interferon-gamma production; 'de novo' protein folding; response to hydrogen peroxide; response to estrogen stimulus; response to heat; response to hypoxia; positive regulation of T cell activation; negative regulation of apoptosis; positive regulation of inflammatory response
Research Articles on 6-OHDA
Precautions
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Pathways associated with 6-OHDA elisa kit
Diseases associated with 6-OHDA elisa kit
Organs/Tissues associated with 6-OHDA elisa kit
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