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ACHE elisa kit :: Pigeon Acetylcholinesterase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS048743 ACHE elisa kit
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Acetylcholinesterase (ACHE), ELISA Kit

 Also Known As   

Pigeon Acetylcholinesterase ELISA Kit

 Product Gene Name   

ACHE elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 7; NC_000007.13 (100487615..100493541, complement). Location: 7q22
 OMIM    100740
 3D Structure    ModBase 3D Structure for P22303
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 Species Reactivity    Pigeon
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ACHE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ACHE purchase    MBS048743 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Acetylcholinesterase (ACHE) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ACHE. The ELISA analytical biochemical technique of the MBS048743 kit is based on ACHE antibody-ACHE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ACHE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ACHE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ACHE. It may not necessarily be applicable to this product.
 NCBI GI #    545225
 NCBI GeneID    43
 NCBI Accession #    AAC60618.1 [Other Products]
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 UniProt Primary Accession #    P22303 [Other Products]
 UniProt Secondary Accession #    Q16169; Q29S23; Q2M324; Q504V3; Q53F46; Q86TM9; Q86YX9; Q9BXP7; A4D2E2; B7ZKZ0; D6W5X7 [Other Products]
 UniProt Related Accession #    P22303 [Other Products]
 Molecular Weight    67,796 Da
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 NCBI Official Full Name    acetylcholinesterase
 NCBI Official Synonym Full Names    acetylcholinesterase
 NCBI Official Symbol    ACHE [Similar Products]
 NCBI Official Synonym Symbols   
YT; ACEE; ARACHE; N-ACHE
[Similar Products]
 NCBI Protein Information    acetylcholinesterase; Yt blood group; apoptosis-related acetylcholinesterase
 UniProt Protein Name    Acetylcholinesterase
 Protein Family    Acetylcholinesterase
 UniProt Gene Name    ACHE [Similar Products]
 UniProt Synonym Gene Names    AChE [Similar Products]
 UniProt Entry Name    ACES_HUMAN
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 NCBI Summary for ACHE    Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ACHE    ACHE: Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis. Belongs to the type-B carboxylesterase/lipase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.1.7; Membrane protein, GPI anchor; Lipid Metabolism - glycerophospholipid; Hydrolase

Chromosomal Location of Human Ortholog: 7q22

Cellular Component: Golgi apparatus; extracellular space; cell surface; membrane; perinuclear region of cytoplasm; extracellular region; plasma membrane; basal lamina; synapse; nucleus; cell junction; neuromuscular junction

Molecular Function: collagen binding; protein binding; serine hydrolase activity; protein homodimerization activity; cholinesterase activity; protein self-association; hydrolase activity; beta-amyloid binding; laminin binding; acetylcholinesterase activity; acetylcholine binding

Biological Process: negative regulation of synaptic transmission, cholinergic; nervous system development; muscle development; acetylcholine catabolic process in synaptic cleft; acetylcholine catabolic process; glycerophospholipid biosynthetic process; osteoblast development; cell proliferation; synaptic transmission; synaptogenesis; positive regulation of protein secretion; amyloid precursor protein metabolic process; retina development in camera-type eye; receptor internalization; phospholipid metabolic process; neurotransmitter receptor biosynthetic process; response to wounding; phosphatidylcholine biosynthetic process; regulation of receptor recycling; DNA replication; cell adhesion; protein tetramerization; neurotransmitter biosynthetic process

Disease: Yt Blood Group Antigen
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 Research Articles on ACHE    1. verify amplification and/or deletion in the ACHE, BCHE, EPHB4 and MME genes in 32 samples of sporadic breast cancer
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ACHE elisa kitDiseases associated with ACHE elisa kit
 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Acetylcholine Synthesis Pathway antibodies  Acetylcholine Synthesis Pathway Diagram
 Biogenic Amine Synthesis Pathway antibodies  Biogenic Amine Synthesis Pathway Diagram
 Cholinergic Synapse Pathway antibodies  Cholinergic Synapse Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >218337 publications with ACHE and Nervous System Diseases
 Neoplasms Antibodies  >61843 publications with ACHE and Neoplasms
 Brain Diseases Antibodies  >27698 publications with ACHE and Brain Diseases
 Inflammation Antibodies  >20873 publications with ACHE and Inflammation
 Death Antibodies  >16098 publications with ACHE and Death
 Fever Antibodies  >15644 publications with ACHE and Fever
 Necrosis Antibodies  >11383 publications with ACHE and Necrosis
 Hypertension Antibodies  >10640 publications with ACHE and Hypertension
 Kidney Diseases Antibodies  >10104 publications with ACHE and Kidney Diseases
 Edema Antibodies  >9725 publications with ACHE and Edema
Organs/Tissues associated with ACHE elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >72474 publications with ACHE and Blood
 Nerve Antibodies  >42257 publications with ACHE and Nerve
 Heart Antibodies  >38103 publications with ACHE and Heart
 Muscle Antibodies  >38087 publications with ACHE and Muscle
 Brain Antibodies  >33200 publications with ACHE and Brain
 Liver Antibodies  >12556 publications with ACHE and Liver
 Kidney Antibodies  >11909 publications with ACHE and Kidney
 Intestine Antibodies  >11049 publications with ACHE and Intestine
 Lung Antibodies  >10544 publications with ACHE and Lung
 Mouth Antibodies  >9233 publications with ACHE and Mouth
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