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CD83 elisa kit :: Pigeon Cluster of Differentiation 83 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS103839 CD83 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cluster of Differentiation 83 (CD83), ELISA Kit

 Also Known As   

Pigeon Cluster of Differentiation 83 ELISA Kit

 Product Gene Name   

CD83 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    101800
 3D Structure    ModBase 3D Structure for P10644
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 Species Reactivity    Pigeon
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of CD83 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CD83 purchase    MBS103839 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cluster of Differentiation 83 (CD83) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CD83. The ELISA analytical biochemical technique of the MBS103839 kit is based on CD83 antibody-CD83 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CD83 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CD83. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CD83. It may not necessarily be applicable to this product.
 NCBI GI #    125193
 NCBI GeneID    5573
 NCBI Accession #    P10644.1 [Other Products]
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 UniProt Primary Accession #    P10644 [Other Products]
 UniProt Secondary Accession #    Q567S7; K7ER48 [Other Products]
 UniProt Related Accession #    P10644 [Other Products]
 Molecular Weight    42,982 Da
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 NCBI Official Full Name    cAMP-dependent protein kinase type I-alpha regulatory subunit
 NCBI Official Synonym Full Names    protein kinase, cAMP-dependent, regulatory, type I, alpha
 NCBI Official Symbol    PRKAR1A [Similar Products]
 NCBI Official Synonym Symbols   
CAR; CNC; CNC1; PKR1; TSE1; ADOHR; PPNAD1; PRKAR1; ACRDYS1
[Similar Products]
 NCBI Protein Information    cAMP-dependent protein kinase type I-alpha regulatory subunit; Carney complex type 1; tissue-specific extinguisher 1; protein kinase A type 1a regulatory subunit; cAMP-dependent protein kinase regulatory subunit RIalpha; cAMP-dependent protein kinase type I-alpha regulatory chain
 UniProt Protein Name    cAMP-dependent protein kinase type I-alpha regulatory subunit
 UniProt Synonym Protein Names   
Tissue-specific extinguisher 1
 Protein Family    CD83 antigen
 UniProt Gene Name    PRKAR1A [Similar Products]
 UniProt Synonym Gene Names    PKR1; PRKAR1; TSE1; TSE1 [Similar Products]
 UniProt Entry Name    KAP0_HUMAN
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 NCBI Summary for CD83    cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. This gene encodes one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Several alternatively spliced transcript variants encoding two different isoforms have been observed. [provided by RefSeq, Jan 2013]
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 UniProt Comments for CD83    PKAR1A: a regulatory subunit of cAMP-regulated protein kinase. The inactive form of the enzyme is composed of two regulatory chains and two catalytic chains. Activation by cAMP produces two active catalytic monomers and a regulatory dimer that binds four cAMP molecules. Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible. Interacts with RFC2: the complex may be involved in cell survival. Defects in PRKAR1A are the cause of Carney complex type 1 (CNC1). CNC is a multiple neoplasia syndrome characterized by spotty skin pigmentation, cardiac and other myxomas, endocrine tumors, and psammomatous melanotic schwannomas.

Protein type: Protein kinase, regulatory subunit

Chromosomal Location of Human Ortholog: 17q24.2

Cellular Component: protein complex; membrane; plasma membrane; neuromuscular junction; cytosol; cAMP-dependent protein kinase complex; AMP-activated protein kinase complex

Molecular Function: protein binding; ubiquitin protein ligase binding; cAMP-dependent protein kinase inhibitor activity; cAMP-dependent protein kinase regulator activity; cAMP binding

Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; activation of protein kinase A; female meiosis; cardiac muscle cell proliferation; sarcomere organization; signal transduction; regulation of transcription from RNA polymerase II promoter; mesoderm formation; phospholipase C activation; negative regulation of meiosis; energy reserve metabolic process; innate immune response; renal water homeostasis; blood coagulation; regulation of insulin secretion; transmembrane transport

Disease: Myxoma, Intracardiac; Carney Complex, Type 1; Thyroid Carcinoma, Papillary; Acrodysostosis 1 With Or Without Hormone Resistance; Pigmented Nodular Adrenocortical Disease, Primary, 1
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 Research Articles on CD83    1. Increased PKA signaling in perirenal adipose tissue was associated with lower BMI in Cushing syndrome. Differences in fat distribution may contribute to phenotypic differences between patients with Cushing syndrome with and without PRKAR1A mutations.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CD83 elisa kitPathways associated with CD83 elisa kit
 Reference Product  PubMed Publications
 GNAS elisa kit  >25 publications with CD83 and GNAS
 PRKAR1B elisa kit  >15 publications with CD83 and PRKAR1B
 PRKACA elisa kit  >7 publications with CD83 and PRKACA
 PRKACB elisa kit  >4 publications with CD83 and PRKACB
 AKAP1 elisa kit  >4 publications with CD83 and AKAP1
 ADCY9 elisa kit  >1 publications with CD83 and ADCY9
 ADCY2 elisa kit  >1 publications with CD83 and ADCY2
 AKAP10 elisa kit  >1 publications with CD83 and AKAP10
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Ca-dependent Events Pathway antibodies  Ca-dependent Events Pathway Diagram
 CaM Pathway antibodies  CaM Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Calmodulin Induced Events Pathway antibodies  Calmodulin Induced Events Pathway Diagram
 DAG And IP3 Signaling Pathway antibodies  DAG And IP3 Signaling Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
Diseases associated with CD83 elisa kitOrgans/Tissues associated with CD83 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >226 publications with CD83 and Neoplasms
 Carney Complex Antibodies  >182 publications with CD83 and Carney Complex
 Cardiovascular Diseases Antibodies  >60 publications with CD83 and Cardiovascular Diseases
 Heart Diseases Antibodies  >58 publications with CD83 and Heart Diseases
 Hyperplasia Antibodies  >51 publications with CD83 and Hyperplasia
 Cushing Syndrome Antibodies  >50 publications with CD83 and Cushing Syndrome
 Disease Models, Animal Antibodies  >28 publications with CD83 and Disease Models, Animal
 Liver Neoplasms Antibodies  >10 publications with CD83 and Liver Neoplasms
 Liver Diseases Antibodies  >7 publications with CD83 and Liver Diseases
 Adrenal Hyperplasia, Congenital Antibodies  >6 publications with CD83 and Adrenal Hyperplasia, Congenital
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >62 publications with CD83 and Skin
 Blood Antibodies  >49 publications with CD83 and Blood
 Thyroid Antibodies  >40 publications with CD83 and Thyroid
 Brain Antibodies  >23 publications with CD83 and Brain
 Embryonic Tissue Antibodies  >16 publications with CD83 and Embryonic Tissue
 Muscle Antibodies  >16 publications with CD83 and Muscle
 Liver Antibodies  >11 publications with CD83 and Liver
 Lung Antibodies  >10 publications with CD83 and Lung
 Testis Antibodies  >9 publications with CD83 and Testis
 Kidney Antibodies  >5 publications with CD83 and Kidney
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