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MAPKAPK3 elisa kit :: Pigeon Mitogen Activated Protein Kinase -Activa Protein Kinase 3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS077469 MAPKAPK3 elisa kit
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 Product Name   

Mitogen Activated Protein Kinase -Activa Protein Kinase 3 (MAPKAPK3), ELISA Kit

 Also Known As   

Pigeon Mitogen Activated Protein Kinase -Activa Protein Kinase 3 ELISA Kit

 Product Gene Name   

MAPKAPK3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 3; NC_000003.11 (50649293..50686728). Location: 3p21.3
 OMIM    602130
 3D Structure    ModBase 3D Structure for Q16644
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 Species Reactivity    Pigeon
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MAPKAPK3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MAPKAPK3 purchase    MBS077469 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Mitogen Activated Protein Kinase -Activa Protein Kinase 3 (MAPKAPK3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MAPKAPK3. The ELISA analytical biochemical technique of the MBS077469 kit is based on MAPKAPK3 antibody-MAPKAPK3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MAPKAPK3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MAPKAPK3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for MAPKAPK3. It may not necessarily be applicable to this product.
 NCBI GI #    345441758
 NCBI GeneID    7867
 NCBI Accession #    NP_001230855.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001243926.1 [Other Products]
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 UniProt Primary Accession #    Q16644 [Other Products]
 UniProt Secondary Accession #    B5BU67 [Other Products]
 UniProt Related Accession #    Q16644 [Other Products]
 Molecular Weight    42,987 Da
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 NCBI Official Full Name    MAP kinase-activated protein kinase 3
 NCBI Official Synonym Full Names    mitogen-activated protein kinase-activated protein kinase 3
 NCBI Official Symbol    MAPKAPK3 [Similar Products]
 NCBI Official Synonym Symbols   
3PK; MK-3; MAPKAP3; MAPKAP-K3; MAPKAPK-3
[Similar Products]
 NCBI Protein Information    MAP kinase-activated protein kinase 3; MAPKAP kinase 3; chromosome 3p kinase; MAPK-activated protein kinase 3
 UniProt Protein Name    MAP kinase-activated protein kinase 3
 UniProt Synonym Protein Names   
Chromosome 3p kinase
 Protein Family    MAP kinase-activated protein kinase
 UniProt Gene Name    MAPKAPK3 [Similar Products]
 UniProt Synonym Gene Names    MAPK-activated protein kinase 3; MAPKAP kinase 3; MAPKAP-K3; MAPKAPK-3; MK-3; 3pK [Similar Products]
 UniProt Entry Name    MAPK3_HUMAN
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 NCBI Summary for MAPKAPK3    This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
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 UniProt Comments for MAPKAPK3    MAPKAPK3: a member of the MAPKAPK family of protein kinases. Activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.

Protein type: Protein kinase, CAMK; EC 2.7.11.1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); CAMK group; MAPKAPK family; MAPKAPK subfamily

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: nucleoplasm; nuclear membrane; cytoplasm; cytosol; nucleus

Molecular Function: MAP kinase kinase activity; protein serine/threonine kinase activity; protein binding; ATP binding

Biological Process: nerve growth factor receptor signaling pathway; activation of MAPK activity; MyD88-independent toll-like receptor signaling pathway; stress-activated MAPK cascade; response to lipopolysaccharide; toll-like receptor 3 signaling pathway; signal transduction; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor 5 signaling pathway; peptidyl-serine phosphorylation; response to cytokine stimulus; Ras protein signal transduction; toll-like receptor signaling pathway; response to stress; innate immune response; toll-like receptor 9 signaling pathway; vascular endothelial growth factor receptor signaling pathway; toll-like receptor 4 signaling pathway
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 Research Articles on MAPKAPK3    1. Hepatitis C virus core protein interacted with MAPKAPK3 through amino acid residues 41 to 75 of core and the N-terminal half of kinase domain of MAPKAPK3.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MAPKAPK3 elisa kitPathways associated with MAPKAPK3 elisa kit
 Reference Product  PubMed Publications
 MAPKAPK2 elisa kit  >31 publications with MAPKAPK3 and MAPKAPK2
 STAT1 elisa kit  >3 publications with MAPKAPK3 and STAT1
 MAPK14 elisa kit  >3 publications with MAPKAPK3 and MAPK14
 HSPB1 elisa kit  >3 publications with MAPKAPK3 and HSPB1
 MAP2K6 elisa kit  >1 publications with MAPKAPK3 and MAP2K6
 MAP2K3 elisa kit  >1 publications with MAPKAPK3 and MAP2K3
 Products by Pathway  Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 FAS Pathway And Stress Induction Of HSP Regulation antibodies  FAS Pathway And Stress Induction Of HSP Regulation Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 MAP Kinase Activation In TLR Cascade Pathway antibodies  MAP Kinase Activation In TLR Cascade Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MyD88 Cascade Initiated On Plasma Membrane Pathway antibodies  MyD88 Cascade Initiated On Plasma Membrane Pathway Diagram
 MyD88 Dependent Cascade Initiated On Endosome Pathway antibodies  MyD88 Dependent Cascade Initiated On Endosome Pathway Diagram
 MyD88-independent Cascade Pathway antibodies  MyD88-independent Cascade Pathway Diagram
Diseases associated with MAPKAPK3 elisa kitOrgans/Tissues associated with MAPKAPK3 elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >9 publications with MAPKAPK3 and Necrosis
 Inflammation Antibodies  >5 publications with MAPKAPK3 and Inflammation
 Disease Models, Animal Antibodies  >3 publications with MAPKAPK3 and Disease Models, Animal
 Liver Diseases Antibodies  >2 publications with MAPKAPK3 and Liver Diseases
 Lung Neoplasms Antibodies  >2 publications with MAPKAPK3 and Lung Neoplasms
 Hepatitis Antibodies  >2 publications with MAPKAPK3 and Hepatitis
 Gastrointestinal Diseases Antibodies  >2 publications with MAPKAPK3 and Gastrointestinal Diseases
 Liver Neoplasms Antibodies  >1 publications with MAPKAPK3 and Liver Neoplasms
 Death Antibodies  >1 publications with MAPKAPK3 and Death
 Heart Diseases Antibodies  >1 publications with MAPKAPK3 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >1 publications with MAPKAPK3 and Embryonic Tissue
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