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SLC22A1 elisa kit :: Pigeon Solute Carrier Family 22 Member 1 (SLC22A1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9346502 SLC22A1 elisa kit
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 Product Name   

Solute Carrier Family 22 Member 1 (SLC22A1), ELISA Kit

★Popular Item★
 Also Known As   

Pigeon Solute Carrier Family 22 Member 1 (SLC22A1) ELISA Kit

 Product Gene Name   

SLC22A1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Species Reactivity    Pigeon
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SLC22A1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SLC22A1 purchase    MBS9346502 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Solute Carrier Family 22 Member 1 (SLC22A1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SLC22A1. The ELISA analytical biochemical technique of the MBS9346502 kit is based on SLC22A1 antibody-SLC22A1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SLC22A1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SLC22A1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for SLC22A1. It may not necessarily be applicable to this product.
 NCBI GI #    6981300
 NCBI GeneID    24904
 NCBI Accession #    NP_036829.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012697.1 [Other Products]
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 UniProt Secondary Accession #    O35882; Q6AYW1 [Other Products]
 UniProt Related Accession #    Q63089 [Other Products]
 Molecular Weight    47,678 Da
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 NCBI Official Full Name    solute carrier family 22 member 1
 NCBI Official Synonym Full Names    solute carrier family 22 member 1
 NCBI Official Symbol    Slc22a1 [Similar Products]
 NCBI Official Synonym Symbols   
Oct1; Orct1; Roct1
[Similar Products]
 NCBI Protein Information    solute carrier family 22 member 1
 UniProt Protein Name    Solute carrier family 22 member 1
 UniProt Synonym Protein Names   
Organic cation transporter 1; rOCT1
 Protein Family    Solute carrier family
 UniProt Gene Name    Slc22a1 [Similar Products]
 UniProt Synonym Gene Names    Oct1; rOCT1 [Similar Products]
 UniProt Entry Name    S22A1_RAT
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 NCBI Summary for SLC22A1    polyspecific transporter involved in exporting ATP-dependent multidrug proteins through the basolateral membrane of renal proximal tubules [RGD, Feb 2006]
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 UniProt Comments for SLC22A1    SLC22A1: Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)- N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH-independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin- dependent kinase II and LCK tyrosine kinase. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter

Cellular Component: basolateral plasma membrane; integral to plasma membrane

Molecular Function: acetylcholine transmembrane transporter activity; dopamine transmembrane transporter activity; identical protein binding; monoamine transmembrane transporter activity; norepinephrine transmembrane transporter activity; organic cation transmembrane transporter activity; protein homodimerization activity; quaternary ammonium group transmembrane transporter activity; secondary active organic cation transmembrane transporter activity

Biological Process: cation transport; dopamine transport; epinephrine transport; establishment and/or maintenance of transmembrane electrochemical gradient; monoamine transport; multidrug transport; neurotransmitter transport; norepinephrine transport; organic cation transport; protein homooligomerization; quaternary ammonium group transport
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 Research Articles on SLC22A1    1. Protein and mRNA expression levels of Oat1, Oat3, Oct1, and Oct2 were significantly decreased in adenine-induced chronic renal failure rats.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SLC22A1 elisa kitPathways associated with SLC22A1 elisa kit
 Reference Product  PubMed Publications
 Abcg2 elisa kit  >21 publications with SLC22A1 and Abcg2
 Slc47a1 elisa kit  >20 publications with SLC22A1 and Slc47a1
 Slc10a1 elisa kit  >8 publications with SLC22A1 and Slc10a1
 Slco1a2 elisa kit  >7 publications with SLC22A1 and Slco1a2
 Slco1a1 elisa kit  >1 publications with SLC22A1 and Slco1a1
 Abcb1a elisa kit  >1 publications with SLC22A1 and Abcb1a
 Abcb1b elisa kit  >1 publications with SLC22A1 and Abcb1b
 Products by Pathway  Pathway Diagram
 Abacavir Transmembrane Transport Pathway antibodies  Abacavir Transmembrane Transport Pathway Diagram
 Abacavir Transport And Metabolism Pathway antibodies  Abacavir Transport And Metabolism Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Choline Metabolism In Cancer Pathway antibodies  Choline Metabolism In Cancer Pathway Diagram
 Choline Metabolism In Cancer Pathway antibodies  Choline Metabolism In Cancer Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Organic Cation Transport Pathway antibodies  Organic Cation Transport Pathway Diagram
 Organic Cation/anion/zwitterion Transport Pathway antibodies  Organic Cation/anion/zwitterion Transport Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
Organs/Tissues associated with SLC22A1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >62 publications with SLC22A1 and Liver
 Kidney Antibodies  >53 publications with SLC22A1 and Kidney
 Heart Antibodies  >5 publications with SLC22A1 and Heart
 Small Intestine Antibodies  >5 publications with SLC22A1 and Small Intestine
 Ovary Antibodies  >3 publications with SLC22A1 and Ovary
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