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VD3 elisa kit :: Pigeon Vitamin D3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS088090 VD3 elisa kit
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Vitamin D3 (VD3), ELISA Kit

 Also Known As   

Pigeon Vitamin D3 ELISA Kit

 Product Gene Name   

VD3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    277440
 3D Structure    ModBase 3D Structure for P11473
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 Species Reactivity    Pigeon
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of VD3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for VD3 purchase    MBS088090 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Vitamin D3 (VD3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing VD3. The ELISA analytical biochemical technique of the MBS088090 kit is based on VD3 antibody-VD3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect VD3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, VD3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for VD3. It may not necessarily be applicable to this product.
 NCBI GI #    63054845
 NCBI GeneID    7421
 NCBI Accession #    NP_001017535.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001017535.1 [Other Products]
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 UniProt Primary Accession #    P11473 [Other Products]
 UniProt Secondary Accession #    Q5PSV3; B2R5Q1; G3V1V9 [Other Products]
 UniProt Related Accession #    P11473 [Other Products]
 Molecular Weight    48,289 Da
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 NCBI Official Full Name    vitamin D3 receptor isoform VDRA
 NCBI Official Synonym Full Names    vitamin D (1,25- dihydroxyvitamin D3) receptor
 NCBI Official Symbol    VDR [Similar Products]
 NCBI Official Synonym Symbols   
NR1I1; PPP1R163
[Similar Products]
 NCBI Protein Information    vitamin D3 receptor; 1,25-dihydroxyvitamin D3 receptor; vitamin D nuclear receptor variant 1; nuclear receptor subfamily 1 group I member 1; protein phosphatase 1, regulatory subunit 163
 UniProt Protein Name    Vitamin D3 receptor
 UniProt Synonym Protein Names   
1,25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1
 Protein Family    Vitamin D3 receptor
 UniProt Gene Name    VDR [Similar Products]
 UniProt Synonym Gene Names    NR1I1; VDR [Similar Products]
 UniProt Entry Name    VDR_HUMAN
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 NCBI Summary for VD3    This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011]
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 UniProt Comments for VD3    VDR: Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. Defects in VDR are the cause of rickets vitamin D- dependent type 2A (VDDR2A). A disorder of vitamin D metabolism resulting in severe rickets, hypocalcemia and secondary hyperparathyroidism. Most patients have total alopecia in addition to rickets. Belongs to the nuclear hormone receptor family. NR1 subfamily.

Protein type: Nuclear receptor; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 12q13.11

Cellular Component: nucleoplasm; nucleus; receptor complex

Molecular Function: retinoid X receptor binding; protein binding; DNA binding; zinc ion binding; sequence-specific DNA binding; steroid hormone receptor activity; vitamin D3 receptor activity; transcription factor activity

Biological Process: lactation; transcription initiation from RNA polymerase II promoter; positive regulation of apoptosis involved in mammary gland involution; cell morphogenesis; negative regulation of transcription from RNA polymerase II promoter; decidualization; signal transduction; intestinal absorption; cellular calcium ion homeostasis; negative regulation of cell proliferation; calcium ion transport; positive regulation of transcription from RNA polymerase II promoter; gene expression; steroid hormone mediated signaling; negative regulation of transcription, DNA-dependent; skeletal development; positive regulation of keratinocyte differentiation

Disease: Vitamin D-dependent Rickets, Type 2a; Osteoporosis
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 Research Articles on VD3    1. a constitutive inhibitory interaction between the inactive vitamin D receptor (VDR) and Stat1, which was released upon stimulation with calcitriol and IFN-alpha.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with VD3 elisa kitPathways associated with VD3 elisa kit
 Reference Product  PubMed Publications
 SRC elisa kit  >87 publications with VD3 and SRC
 NCOA1 elisa kit  >39 publications with VD3 and NCOA1
 MED1 elisa kit  >31 publications with VD3 and MED1
 NCOR1 elisa kit  >28 publications with VD3 and NCOR1
 NCOA2 elisa kit  >12 publications with VD3 and NCOA2
 RXRA elisa kit  >11 publications with VD3 and RXRA
 NCOA3 elisa kit  >10 publications with VD3 and NCOA3
 CREBBP elisa kit  >6 publications with VD3 and CREBBP
 EP300 elisa kit  >4 publications with VD3 and EP300
 SNW1 elisa kit  >4 publications with VD3 and SNW1
 Products by Pathway  Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 Drug Induction Of Bile Acid Pathway antibodies  Drug Induction Of Bile Acid Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 Nuclear Receptor Transcription Pathway antibodies  Nuclear Receptor Transcription Pathway Diagram
 Nuclear Receptors Pathway antibodies  Nuclear Receptors Pathway Diagram
Diseases associated with VD3 elisa kitOrgans/Tissues associated with VD3 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >935 publications with VD3 and Neoplasms
 Osteoporosis Antibodies  >417 publications with VD3 and Osteoporosis
 Vitamin D Deficiency Antibodies  >381 publications with VD3 and Vitamin D Deficiency
 Kidney Diseases Antibodies  >304 publications with VD3 and Kidney Diseases
 Breast Neoplasms Antibodies  >210 publications with VD3 and Breast Neoplasms
 Rickets Antibodies  >202 publications with VD3 and Rickets
 Inflammation Antibodies  >189 publications with VD3 and Inflammation
 Prostatic Neoplasms Antibodies  >169 publications with VD3 and Prostatic Neoplasms
 Cardiovascular Diseases Antibodies  >167 publications with VD3 and Cardiovascular Diseases
 Hypercalcemia Antibodies  >130 publications with VD3 and Hypercalcemia
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1247 publications with VD3 and Bone
 Blood Antibodies  >936 publications with VD3 and Blood
 Kidney Antibodies  >533 publications with VD3 and Kidney
 Parathyroid Antibodies  >395 publications with VD3 and Parathyroid
 Intestine Antibodies  >304 publications with VD3 and Intestine
 Skin Antibodies  >293 publications with VD3 and Skin
 Prostate Antibodies  >257 publications with VD3 and Prostate
 Connective Tissue Antibodies  >200 publications with VD3 and Connective Tissue
 Muscle Antibodies  >170 publications with VD3 and Muscle
 Lung Antibodies  >110 publications with VD3 and Lung
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