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XRCC6 elisa kit :: Pigeon X-Ray Repair Cross Complementing 6 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS093068 XRCC6 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

X-Ray Repair Cross Complementing 6 (XRCC6), ELISA Kit

 Also Known As   

Pigeon X-Ray Repair Cross Complementing 6 ELISA Kit

 Product Gene Name   

XRCC6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    194360
 3D Structure    ModBase 3D Structure for P18887
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 Species Reactivity    Pigeon
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of XRCC6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for XRCC6 purchase    MBS093068 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the X-Ray Repair Cross Complementing 6 (XRCC6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing XRCC6. The ELISA analytical biochemical technique of the MBS093068 kit is based on XRCC6 antibody-XRCC6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect XRCC6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, XRCC6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for XRCC6. It may not necessarily be applicable to this product.
 NCBI GI #    62087142
 NCBI GeneID    7515
 NCBI Accession #    BAD92018.1 [Other Products]
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 UniProt Primary Accession #    P18887 [Other Products]
 UniProt Secondary Accession #    Q6IBS4; Q9HCB1 [Other Products]
 UniProt Related Accession #    P18887 [Other Products]
 Molecular Weight    69,477 Da
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 NCBI Official Full Name    X-ray repair cross complementing protein 1 variant, partial
 NCBI Official Synonym Full Names    X-ray repair complementing defective repair in Chinese hamster cells 1
 NCBI Official Symbol    XRCC1 [Similar Products]
 NCBI Official Synonym Symbols   
RCC
[Similar Products]
 NCBI Protein Information    DNA repair protein XRCC1; X-ray repair cross-complementing protein 1
 UniProt Protein Name    DNA repair protein XRCC1
 UniProt Synonym Protein Names   
X-ray repair cross-complementing protein 1
 Protein Family    X-ray repair cross-complementing protein
 UniProt Gene Name    XRCC1 [Similar Products]
 UniProt Entry Name    XRCC1_HUMAN
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 NCBI Summary for XRCC6    The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
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 UniProt Comments for XRCC6    XRCC1: Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Homodimer. Interacts with polynucleotide kinase (PNK), DNA polymerase-beta (POLB) and DNA ligase III (LIG3). Interacts with APTX and APLF. Interacts with APEX1; the interaction is induced by SIRT1 and increases with the acetylated form of APEX1.

Protein type: DNA repair, damage

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; enzyme binding; damaged DNA binding

Biological Process: single strand break repair; base-excision repair; DNA repair
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 Research Articles on XRCC6    1. meta-analysis indicate that XRCC1 Arg399Gln polymorphism may be associated with poor clinical outcomes in gastric cancer patients treated with oxaliplatin-based chemotherapy
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with XRCC6 elisa kitPathways associated with XRCC6 elisa kit
 Reference Product  PubMed Publications
 APEX1 elisa kit  >100 publications with XRCC6 and APEX1
 PARP1 elisa kit  >80 publications with XRCC6 and PARP1
 LIG3 elisa kit  >29 publications with XRCC6 and LIG3
 APTX elisa kit  >15 publications with XRCC6 and APTX
 TDP1 elisa kit  >14 publications with XRCC6 and TDP1
 PNKP elisa kit  >12 publications with XRCC6 and PNKP
 POLB elisa kit  >12 publications with XRCC6 and POLB
 POLD1 elisa kit  >6 publications with XRCC6 and POLD1
 APLF elisa kit  >4 publications with XRCC6 and APLF
 PARP2 elisa kit  >1 publications with XRCC6 and PARP2
 Products by Pathway  Pathway Diagram
 BER Complex Pathway antibodies  BER Complex Pathway Diagram
 BER Complex Pathway antibodies  BER Complex Pathway Diagram
 Base Excision Repair Pathway antibodies  Base Excision Repair Pathway Diagram
 Base Excision Repair Pathway antibodies  Base Excision Repair Pathway Diagram
 Base Excision Repair Pathway antibodies  Base Excision Repair Pathway Diagram
 DNA Repair Pathway antibodies  DNA Repair Pathway Diagram
 E2F Transcription Factor Network Pathway antibodies  E2F Transcription Factor Network Pathway Diagram
 FOXM1 Transcription Factor Network Pathway antibodies  FOXM1 Transcription Factor Network Pathway Diagram
 Resolution Of AP Sites Via The Single-nucleotide Replacement Pathway antibodies  Resolution Of AP Sites Via The Single-nucleotide Replacement Pathway Diagram
 Resolution Of Abasic Sites (AP Sites) Pathway antibodies  Resolution Of Abasic Sites (AP Sites) Pathway Diagram
Diseases associated with XRCC6 elisa kitOrgans/Tissues associated with XRCC6 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >810 publications with XRCC6 and Neoplasms
 Carcinoma Antibodies  >323 publications with XRCC6 and Carcinoma
 Lung Diseases Antibodies  >154 publications with XRCC6 and Lung Diseases
 Lung Neoplasms Antibodies  >152 publications with XRCC6 and Lung Neoplasms
 Adenocarcinoma Antibodies  >121 publications with XRCC6 and Adenocarcinoma
 Breast Neoplasms Antibodies  >113 publications with XRCC6 and Breast Neoplasms
 Carcinoma, Squamous Cell Antibodies  >101 publications with XRCC6 and Carcinoma, Squamous Cell
 Chromosome Aberrations Antibodies  >73 publications with XRCC6 and Chromosome Aberrations
 Stomach Neoplasms Antibodies  >52 publications with XRCC6 and Stomach Neoplasms
 Urinary Bladder Neoplasms Antibodies  >47 publications with XRCC6 and Urinary Bladder Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >240 publications with XRCC6 and Blood
 Lung Antibodies  >194 publications with XRCC6 and Lung
 Bladder Antibodies  >57 publications with XRCC6 and Bladder
 Liver Antibodies  >50 publications with XRCC6 and Liver
 Brain Antibodies  >46 publications with XRCC6 and Brain
 Prostate Antibodies  >38 publications with XRCC6 and Prostate
 Skin Antibodies  >32 publications with XRCC6 and Skin
 Ovary Antibodies  >30 publications with XRCC6 and Ovary
 Thyroid Antibodies  >22 publications with XRCC6 and Thyroid
 Bone Antibodies  >14 publications with XRCC6 and Bone
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