NP_001100278.1
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NCBI GenBank Nucleotide #
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UniProt Related Accession #
Molecular Weight
42,638 Da
NCBI Official Full Name
neuropeptide S receptor
NCBI Official Synonym Full Names
neuropeptide S receptor 1
NCBI Official Synonym Symbols
NCBI Protein Information
neuropeptide S receptor
UniProt Protein Name
Neuropeptide S receptor
UniProt Synonym Protein Names
G-protein coupled receptor 154
UniProt Synonym Gene Names
UniProt Entry Name
NPSR1_RAT
UniProt Comments for NPSR
NPSR1: May be active in signaling pathway in an autocrine or paracrine fashion in several tissues. Receptor for neuropeptide S, it may mediate its action, such as inhibitory effects, on cell growth. Involved in pathogenesis of asthma and other IgE-mediated diseases. Defects in NPSR1 are a cause of asthma-related traits type 2 (ASRT2). Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, dyspnea, bronchial hyperresponsiveness as assessed by methacholine challenge test, serum IgE levels, atopy and atopic dermatitis. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. 9 isoforms of the human protein are produced by alternative splicing.
Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR
Cellular Component: cytoplasm; integral to plasma membrane
Molecular Function: neuropeptide receptor activity
Biological Process: eating behavior; neuropeptide signaling pathway; positive regulation of release of sequestered calcium ion into cytosol; righting reflex
Research Articles on NPSR
Precautions
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Pathways associated with NPSR elisa kit
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