KFZ60428.1
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UniProt Primary Accession #
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Molecular Weight
148,548 Da
NCBI Official Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, partial
UniProt Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
UniProt Synonym Protein Names
Phosphoinositide phospholipase C-gamma-1; Phospholipase C-gamma-1; PLC-gamma-1
UniProt Synonym Gene Names
UniProt Entry Name
PLCG1_RAT
UniProt Comments for PLCG1
PLCG1: a calcium dependent phosphatidylinositol-specific phospholipase C. The activated enzyme produces the second messenger molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylated and activated by tyrosine kinases in response to signaling through a variety of growth factor receptors and immune system receptors.
Protein type: EC 3.1.4.11; Phospholipase; Motility/polarity/chemotaxis; Carbohydrate Metabolism - inositol phosphate
Cellular Component: signalosome; ruffle; neuron projection; cell projection; lamellipodium; cytoplasm; plasma membrane; intercellular junction; cytosol
Molecular Function: signal transducer activity; protein binding; glutamate receptor binding; neurotrophin TRKA receptor binding; phosphoprotein binding; calcium ion binding; receptor tyrosine kinase binding; phosphoinositide phospholipase C activity; protein kinase binding; insulin receptor binding
Biological Process: epidermal growth factor receptor signaling pathway; response to gravity; cell migration; phospholipid catabolic process; in utero embryonic development; positive regulation of blood vessel endothelial cell migration; protein secretion; calcium-mediated signaling; response to morphine; response to organic nitrogen; signal transduction; T cell receptor signaling pathway; positive regulation of angiogenesis; response to hydrogen peroxide; inositol trisphosphate biosynthetic process; calcium ion transport; positive regulation of release of sequestered calcium ion into cytosol
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Products associated with PLCG1 elisa kit
Diseases associated with PLCG1 elisa kit
Organs/Tissues associated with PLCG1 elisa kit
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