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SFN elisa kit :: Porcine 14-3-3 protein sigma (SFN) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7226585 SFN elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

14-3-3 protein sigma (SFN), ELISA Kit

 Also Known As   

Porcine 14-3-3 protein sigma (SFN) ELISA Kit

 Product Gene Name   

SFN elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    601290
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 Species Reactivity    Porcine
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SFN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SFN purchase    MBS7226585 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 14-3-3 protein sigma (SFN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SFN. The ELISA analytical biochemical technique of the MBS7226585 kit is based on SFN antibody-SFN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SFN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SFN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for SFN elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for SFN. It may not necessarily be applicable to this product.
 NCBI GI #    5454052
 NCBI GeneID    2810
 NCBI Accession #    NP_006133.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006142.3 [Other Products]
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 UniProt Secondary Accession #    Q6FH30; Q6FH51; Q96DH0 [Other Products]
 UniProt Related Accession #    P31947 [Other Products]
 Molecular Weight    24,336 Da [Similar Products]
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 NCBI Official Full Name    14-3-3 protein sigma
 NCBI Official Synonym Full Names    stratifin
 NCBI Official Symbol    SFN [Similar Products]
 NCBI Official Synonym Symbols   
YWHAS
[Similar Products]
 NCBI Protein Information    14-3-3 protein sigma; 14-3-3 sigma; epithelial cell marker protein 1
 UniProt Protein Name    14-3-3 protein sigma
 UniProt Synonym Protein Names   
Epithelial cell marker protein 1; Stratifin
 Protein Family    14-3-3 protein
 UniProt Gene Name    SFN [Similar Products]
 UniProt Synonym Gene Names    HME1 [Similar Products]
 UniProt Entry Name    1433S_HUMAN
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 UniProt Comments for SFN    14-3-3 sigma: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. Homodimer. Interacts with KRT17 and SAMSN1. Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. Interacts with GAB2. Interacts with SRPK2. Present mainly in tissues enriched in stratified squamous keratinizing epithelium. Belongs to the 14-3-3 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: extracellular space; cytoplasmic vesicle membrane; cytoplasm; nucleus; cytosol

Molecular Function: protein domain specific binding; protein kinase C inhibitor activity; protein binding; phosphoprotein binding; protein kinase binding

Biological Process: positive regulation of protein export from nucleus; release of cytochrome c from mitochondria; regulation of epidermal cell division; DNA damage response, signal transduction resulting in induction of apoptosis; apoptosis; keratinization; positive regulation of epidermal cell differentiation; negative regulation of protein kinase activity; regulation of cyclin-dependent protein kinase activity; negative regulation of caspase activity; signal transduction; positive regulation of cell growth
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 Research Articles on SFN    1. Decreased expression of immunoreactive 14-3-3sigma may be a predictor of poor prognosis in patients with uterine papillary serous carcinoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SFN elisa kitPathways associated with SFN elisa kit
 Reference Product  PubMed Publications
 CCNB1 elisa kit  >19 publications with SFN and CCNB1
 TP53 elisa kit  >14 publications with SFN and TP53
 MDM2 elisa kit  >10 publications with SFN and MDM2
 MMP1 elisa kit  >3 publications with SFN and MMP1
 TRIM25 elisa kit  >3 publications with SFN and TRIM25
 BAD elisa kit  >3 publications with SFN and BAD
 CDC25B elisa kit  >2 publications with SFN and CDC25B
 TSC2 elisa kit  >1 publications with SFN and TSC2
 Products by Pathway  Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Class I PI3K Signaling Events Mediated By Akt Pathway antibodies  Class I PI3K Signaling Events Mediated By Akt Pathway Diagram
Diseases associated with SFN elisa kitOrgans/Tissues associated with SFN elisa kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >171 publications with SFN and Carcinoma
 Nervous System Diseases Antibodies  >91 publications with SFN and Nervous System Diseases
 Breast Neoplasms Antibodies  >80 publications with SFN and Breast Neoplasms
 Adenocarcinoma Antibodies  >77 publications with SFN and Adenocarcinoma
 Inflammation Antibodies  >52 publications with SFN and Inflammation
 Necrosis Antibodies  >48 publications with SFN and Necrosis
 Prostatic Neoplasms Antibodies  >41 publications with SFN and Prostatic Neoplasms
 Disease Models, Animal Antibodies  >36 publications with SFN and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >36 publications with SFN and Neoplasm Metastasis
 Lung Neoplasms Antibodies  >36 publications with SFN and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >112 publications with SFN and Skin
 Blood Antibodies  >104 publications with SFN and Blood
 Nerve Antibodies  >77 publications with SFN and Nerve
 Prostate Antibodies  >60 publications with SFN and Prostate
 Lung Antibodies  >54 publications with SFN and Lung
 Liver Antibodies  >48 publications with SFN and Liver
 Brain Antibodies  >42 publications with SFN and Brain
 Thyroid Antibodies  >29 publications with SFN and Thyroid
 Muscle Antibodies  >28 publications with SFN and Muscle
 Lymph Node Antibodies  >28 publications with SFN and Lymph Node
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