NP_071565.2
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
60,955 Da
NCBI Official Full Name
60 kDa heat shock protein, mitochondrial
NCBI Official Synonym Full Names
heat shock protein 1 (chaperonin)
NCBI Protein Information
60 kDa heat shock protein, mitochondrial; CPN60; HSP-60; HSP-65; chaperonin 60; 60 kDa chaperonin; heat shock 60kDa protein 1; heat shock protein 60 (liver); mitochondrial matrix protein P1; heat shock 60kD protein 1 (chaperonin)
UniProt Protein Name
60 kDa heat shock protein, mitochondrial
UniProt Synonym Protein Names
60 kDa chaperonin; Chaperonin 60; CPN60; HSP-65; Heat shock protein 60; HSP-60; Hsp60; Mitochondrial matrix protein P1
UniProt Synonym Gene Names
UniProt Entry Name
CH60_RAT
NCBI Summary for 6-OHDA
a stress-inducible molecular chaperone which participates in protein folding [RGD, Feb 2006]
UniProt Comments for 6-OHDA
HSP60: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. Interacts with HRAS. Interacts with HBV protein X and HTLV-1 protein p40tax. Belongs to the chaperonin (HSP60) family.
Protein type: Mitochondrial; Chaperone
Cellular Component: Golgi apparatus; extracellular space; cell surface; protein complex; rough endoplasmic reticulum; mitochondrion; intracellular membrane-bound organelle; early endosome; coated pit; cytosol; secretory granule; lipid raft; mitochondrial crista; membrane; mitochondrial matrix; mitochondrial inner membrane; cytoplasm; plasma membrane; lipopolysaccharide receptor complex; cyclin-dependent protein kinase activating kinase holoenzyme complex; myelin sheath
Molecular Function: insulin binding; protein binding; protease binding; lipopolysaccharide binding; p53 binding; protein heterodimerization activity; ubiquitin protein ligase binding; chaperone binding; double-stranded RNA binding; protein complex binding; misfolded protein binding; ATP binding
Biological Process: B cell proliferation; T cell activation; positive regulation of apoptosis; positive regulation of interleukin-12 production; isotype switching to IgG isotypes; response to lipopolysaccharide; response to organic cyclic substance; positive regulation of interleukin-10 production; response to organic substance; protein refolding; negative regulation of neuron apoptosis; positive regulation of T cell mediated immune response to tumor cell; positive regulation of interferon-alpha production; positive regulation of macrophage activation; caspase activation; response to drug; protein stabilization; B cell activation; chaperone cofactor-dependent protein folding; positive regulation of interleukin-6 production; detection of misfolded protein; B cell cytokine production; response to cocaine; response to unfolded protein; response to ATP; MyD88-dependent toll-like receptor signaling pathway; positive regulation of interferon-gamma production; 'de novo' protein folding; response to hydrogen peroxide; response to heat; response to estrogen stimulus; response to hypoxia; positive regulation of T cell activation; positive regulation of inflammatory response; negative regulation of apoptosis
Research Articles on 6-OHDA
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with 6-OHDA elisa kit
Diseases associated with 6-OHDA elisa kit
Organs/Tissues associated with 6-OHDA elisa kit
|