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ADAM8 elisa kit :: Porcine A Disintegrin And Metalloprotease 8 (ADAM8) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS267301 ADAM8 elisa kit
Unit / Price
48-Strip-Wells  /  $300 +1 FREE 8GB USB
96-Strip-Wells  /  $475 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Disintegrin And Metalloprotease 8 (ADAM8), ELISA Kit

 Also Known As   

Porcine A Disintegrin And Metalloprotease 8 (ADAM8) ELISA Kit

 Product Gene Name   

ADAM8 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    605175
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 Species Reactivity    Porcine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ADAM8 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ADAM8 purchase    MBS267301 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin And Metalloprotease 8 (ADAM8) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ADAM8. The ELISA analytical biochemical technique of the MBS267301 kit is based on ADAM8 antibody-ADAM8 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADAM8 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADAM8. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ADAM8. It may not necessarily be applicable to this product.
 NCBI GI #    153792351
 NCBI GeneID    11095
 NCBI Accession #    NP_008968.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_007037.4 [Other Products]
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 UniProt Secondary Accession #    Q9NZS0 [Other Products]
 UniProt Related Accession #    Q9UP79 [Other Products]
 Molecular Weight    96,460 Da
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 8 preproprotein
 NCBI Official Synonym Full Names    ADAM metallopeptidase with thrombospondin type 1 motif, 8
 NCBI Official Symbol    ADAMTS8 [Similar Products]
 NCBI Official Synonym Symbols   
METH2; ADAM-TS8
[Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 8; METH-2; METH-8; ADAMTS-8; ADAM-TS 8; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 8
 UniProt Synonym Protein Names   
METH-2; METH-8
 Protein Family    Disintegrin and metalloproteinase domain-containing protein
 UniProt Gene Name    ADAMTS8 [Similar Products]
 UniProt Synonym Gene Names    METH2; ADAM-TS 8; ADAM-TS8; ADAMTS-8 [Similar Products]
 UniProt Entry Name    ATS8_HUMAN
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 NCBI Summary for ADAM8    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADAM8    ADAMTS8: Has anti-angiogenic properties.

Protein type: Protease; Cell cycle regulation; Motility/polarity/chemotaxis; Secreted; EC 3.4.24.-; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11q25

Cellular Component: extracellular matrix; proteinaceous extracellular matrix

Molecular Function: integrin binding; heparin binding; zinc ion binding; metallopeptidase activity; metalloendopeptidase activity; low affinity phosphate transmembrane transporter activity

Biological Process: negative regulation of cell proliferation; proteolysis
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 Research Articles on ADAM8    1. ADAMTS 8, CCL23, and TNFSF15 are implicated in anti-angiogenic activities
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ADAM8 elisa kitDiseases associated with ADAM8 elisa kit
 Products by Pathway  Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 O-glycosylation Of TSR Domain-containing Proteins Pathway antibodies  O-glycosylation Of TSR Domain-containing Proteins Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >6 publications with ADAM8 and Cardiovascular Diseases
 Adenocarcinoma Antibodies  >4 publications with ADAM8 and Adenocarcinoma
 Disease Models, Animal Antibodies  >3 publications with ADAM8 and Disease Models, Animal
 Necrosis Antibodies  >3 publications with ADAM8 and Necrosis
 Brain Diseases Antibodies  >2 publications with ADAM8 and Brain Diseases
 Liver Diseases Antibodies  >1 publications with ADAM8 and Liver Diseases
 Hypertension Antibodies  >1 publications with ADAM8 and Hypertension
 Myocardial Infarction Antibodies  >1 publications with ADAM8 and Myocardial Infarction
 Lung Diseases Antibodies  >1 publications with ADAM8 and Lung Diseases
Organs/Tissues associated with ADAM8 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >4 publications with ADAM8 and Heart
 Lung Antibodies  >3 publications with ADAM8 and Lung
 Brain Antibodies  >2 publications with ADAM8 and Brain
 Connective Tissue Antibodies  >1 publications with ADAM8 and Connective Tissue
 Pancreas Antibodies  >1 publications with ADAM8 and Pancreas
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