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APRIL elisa kit :: Porcine A Proliferation inducing ligand ELISA Kit

Scan QR to view Datasheet Catalog #    MBS744061 APRIL elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Proliferation inducing ligand (APRIL), ELISA Kit

 Also Known As   

Porcine A Proliferation inducing ligand ELISA Kit

 Product Gene Name   

APRIL elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    604472
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 Species Reactivity    Porcine
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of APRIL elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for APRIL purchase    MBS744061 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Proliferation inducing ligand (APRIL) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing APRIL. The ELISA analytical biochemical technique of the MBS744061 kit is based on APRIL antibody-APRIL antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect APRIL antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, APRIL. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for APRIL elisa kit    Immunology
NCBI/Uniprot data below describe general gene information for APRIL. It may not necessarily be applicable to this product.
 NCBI GI #    24934972
 NCBI GeneID    8741
 NCBI Accession #    AAL90442.1 [Other Products]
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 UniProt Secondary Accession #    Q541E1; Q5U0G8; Q96HV6; Q9P1M8; Q9P1M9; A8MYD5; B4DVT2 [Other Products]
 UniProt Related Accession #    O75888 [Other Products]
 Molecular Weight    36,589 Da
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 NCBI Official Full Name    APRIL
 NCBI Official Synonym Full Names    tumor necrosis factor (ligand) superfamily, member 13
 NCBI Official Symbol    TNFSF13 [Similar Products]
 NCBI Official Synonym Symbols   
APRIL; CD256; TALL2; ZTNF2; TALL-2; TRDL-1; UNQ383/PRO715
[Similar Products]
 NCBI Protein Information    tumor necrosis factor ligand superfamily member 13; a proliferation-inducing ligand; tumor necrosis factor-like protein ZTNF2; tumor necrosis factor-related death ligand-1; TNF- and APOL-related leukocyte expressed ligand 2
 UniProt Protein Name    Tumor necrosis factor ligand superfamily member 13
 UniProt Synonym Protein Names   
A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD_antigen: CD256
 UniProt Gene Name    TNFSF13 [Similar Products]
 UniProt Synonym Gene Names    APRIL; TALL2; ZTNF2; UNQ383/PRO715; APRIL; TALL-2; TRDL-1 [Similar Products]
 UniProt Entry Name    TNF13_HUMAN
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 NCBI Summary for APRIL    The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
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 UniProt Comments for APRIL    TNFSF13: Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. May be implicated in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. Belongs to the tumor necrosis factor family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: nucleoplasm; extracellular space; cytoplasm; cytosol; external side of plasma membrane

Molecular Function: cytokine activity; tumor necrosis factor receptor binding; receptor binding

Biological Process: immunoglobulin production in mucosal tissue; positive regulation of cell proliferation; positive regulation of germinal center formation; gene expression; signal transduction; positive regulation of isotype switching to IgA isotypes
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 Research Articles on APRIL    1. The levels of APRIL correlate with the progression of childhood ALL, which may provide certain clues for monitoring ALL clinically.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with APRIL elisa kitPathways associated with APRIL elisa kit
 Reference Product  PubMed Publications
 TNFSF13B elisa kit  >94 publications with APRIL and TNFSF13B
 TNFRSF17 elisa kit  >60 publications with APRIL and TNFRSF17
 TNFRSF13B elisa kit  >45 publications with APRIL and TNFRSF13B
 SET elisa kit  >8 publications with APRIL and SET
 FURIN elisa kit  >5 publications with APRIL and FURIN
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 HuR Stabilizes MRNA Pathway antibodies  HuR Stabilizes MRNA Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway antibodies  Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway Diagram
 Rheumatoid Arthritis Pathway antibodies  Rheumatoid Arthritis Pathway Diagram
 Rheumatoid Arthritis Pathway antibodies  Rheumatoid Arthritis Pathway Diagram
 Spinal Cord Injury Pathway antibodies  Spinal Cord Injury Pathway Diagram
Diseases associated with APRIL elisa kitOrgans/Tissues associated with APRIL elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >214 publications with APRIL and Necrosis
 Inflammation Antibodies  >20 publications with APRIL and Inflammation
 Disease Models, Animal Antibodies  >13 publications with APRIL and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >11 publications with APRIL and Cardiovascular Diseases
 Colorectal Neoplasms Antibodies  >11 publications with APRIL and Colorectal Neoplasms
 Nervous System Diseases Antibodies  >9 publications with APRIL and Nervous System Diseases
 Kidney Diseases Antibodies  >6 publications with APRIL and Kidney Diseases
 Liver Neoplasms Antibodies  >5 publications with APRIL and Liver Neoplasms
 Neoplasms, Experimental Antibodies  >5 publications with APRIL and Neoplasms, Experimental
 Liver Diseases Antibodies  >4 publications with APRIL and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >162 publications with APRIL and Blood
 Bone Antibodies  >20 publications with APRIL and Bone
 Spleen Antibodies  >16 publications with APRIL and Spleen
 Lung Antibodies  >11 publications with APRIL and Lung
 Kidney Antibodies  >10 publications with APRIL and Kidney
 Lymph Node Antibodies  >9 publications with APRIL and Lymph Node
 Skin Antibodies  >7 publications with APRIL and Skin
 Liver Antibodies  >6 publications with APRIL and Liver
 Vascular Antibodies  >5 publications with APRIL and Vascular
 Mouth Antibodies  >3 publications with APRIL and Mouth
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