NP_006764.3
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
75,407 Da
NCBI Official Full Name
ATP-dependent RNA helicase DDX18
NCBI Official Synonym Full Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
NCBI Official Synonym Symbols
NCBI Protein Information
ATP-dependent RNA helicase DDX18; DEAD box protein 18; Myc-regulated DEAD box protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 18 (Myc-regulated)
UniProt Protein Name
ATP-dependent RNA helicase DDX18
UniProt Synonym Protein Names
DEAD box protein 18; Myc-regulated DEAD box protein; MrDb
UniProt Synonym Gene Names
UniProt Entry Name
DDX18_HUMAN
NCBI Summary for DDX18
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it is activated by Myc protein. [provided by RefSeq, Jul 2008]
UniProt Comments for DDX18
DDX18: Probable RNA-dependent helicase. Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
Protein type: RNA-binding; Helicase; EC 3.6.4.13; Nucleolus
Chromosomal Location of Human Ortholog: 2q14.1
Cellular Component: membrane; nucleolus
Molecular Function: protein binding; ATP binding; ATP-dependent RNA helicase activity
Biological Process: metabolic process
Research Articles on DDX18
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Products associated with DDX18 elisa kit
Pathways associated with DDX18 elisa kit
Organs/Tissues associated with DDX18 elisa kit
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