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ADA elisa kit :: Porcine Adenosine Deaminase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS009751 ADA elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Adenosine Deaminase (ADA), ELISA Kit

 Also Known As   

Porcine Adenosine Deaminase ELISA Kit

 Product Gene Name   

ADA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 Chromosome Location    Chromosome: 20; NC_000020.10 (43248163..43280376, complement). Location: 20q13.12
 OMIM    102700
 3D Structure    ModBase 3D Structure for P00813
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 Species Reactivity    Porcine
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of ADA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ADA purchase    MBS009751 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Adenosine Deaminase (ADA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ADA. The ELISA analytical biochemical technique of the MBS009751 kit is based on ADA antibody-ADA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ADA. It may not necessarily be applicable to this product.
 NCBI GI #    47078295
 NCBI GeneID    100
 NCBI Accession #    NP_000013.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000022.2 [Other Products]
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 UniProt Primary Accession #    P00813 [Other Products]
 UniProt Secondary Accession #    Q53F92; Q6LA59 [Other Products]
 UniProt Related Accession #    P00813 [Other Products]
 Molecular Weight    40,764 Da
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 NCBI Official Full Name    adenosine deaminase
 NCBI Official Synonym Full Names    adenosine deaminase
 NCBI Official Symbol    ADA [Similar Products]
 NCBI Protein Information    adenosine deaminase; adenosine aminohydrolase
 UniProt Protein Name    Adenosine deaminase
 UniProt Synonym Protein Names   
Adenosine aminohydrolase
 Protein Family    Adenosine deaminase
 UniProt Gene Name    ADA [Similar Products]
 UniProt Synonym Gene Names    ADA1 [Similar Products]
 UniProt Entry Name    ADA_HUMAN
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 NCBI Summary for ADA    This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADA    ADA: a enzyme that converts adenosine + H2O into inosine + NH3. Found in all tissues, occurs in large amounts in T-lymphocytes and, at the time of weaning, in gastrointestinal tissues. Genetic ADA deficiencies are a cause of autosomal recessive severe combined immuno-deficiency (SCID). Hereditary hemolytic anemia is caused by expression levels in erythrocytes 50-70 times greater than the norm.

Protein type: Nucleotide Metabolism - purine; EC 3.5.4.4; Hydrolase

Chromosomal Location of Human Ortholog: 20q13.12

Cellular Component: dendrite cytoplasm; extracellular space; cell surface; cell soma; membrane; lysosome; cytoplasm; plasma membrane; cell junction; cytosol; external side of plasma membrane

Molecular Function: adenosine deaminase activity; protein binding; zinc ion binding; purine nucleoside binding

Biological Process: negative regulation of circadian sleep/wake cycle, non-REM sleep; T cell activation; adenosine catabolic process; deoxyadenosine catabolic process; response to morphine; positive regulation of calcium-mediated signaling; purine salvage; histamine secretion; positive regulation of T cell differentiation in the thymus; purine ribonucleoside monophosphate biosynthetic process; regulation of cell-cell adhesion mediated by integrin; response to vitamin E; negative regulation of mature B cell apoptosis; positive regulation of T cell receptor signaling pathway; positive regulation of B cell proliferation; positive regulation of germinal center formation; hypoxanthine salvage; negative regulation of adenosine receptor signaling pathway; positive regulation of smooth muscle contraction; embryonic gut development; aging; placenta development; Peyer's patch development; response to drug; nucleobase, nucleoside and nucleotide metabolic process; dATP catabolic process; positive regulation of heart rate; liver development; negative regulation of leukocyte migration; purine base metabolic process; trophectodermal cell differentiation; purine nucleotide salvage; response to hydrogen peroxide; xanthine biosynthetic process; negative regulation of inflammatory response; response to hypoxia; inosine biosynthetic process; germinal center B cell differentiation; alveolus development; positive regulation of alpha-beta T cell differentiation

Disease: Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-negative, B Cell-negative, Nk Cell-negative, Due To Adenosine Deaminase Deficiency
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 Research Articles on ADA    1. Taken together, these findings suggest that ADA would promote enhanced and correctly polarized T-cell responses in strategies targeting asymptomatic HIV-infected individuals.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ADA elisa kitPathways associated with ADA elisa kit
 Reference Product  PubMed Publications
 PNP elisa kit  >152 publications with ADA and PNP
 ADORA1 elisa kit  >63 publications with ADA and ADORA1
 CDA elisa kit  >25 publications with ADA and CDA
 DPP4 elisa kit  >19 publications with ADA and DPP4
 APRT elisa kit  >16 publications with ADA and APRT
 DCK elisa kit  >10 publications with ADA and DCK
 MYB elisa kit  >6 publications with ADA and MYB
 ADK elisa kit  >2 publications with ADA and ADK
 NT5E elisa kit  >1 publications with ADA and NT5E
 Products by Pathway  Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Primary Immunodeficiency Pathway antibodies  Primary Immunodeficiency Pathway Diagram
 Primary Immunodeficiency Pathway antibodies  Primary Immunodeficiency Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Salvage Pathway antibodies  Purine Salvage Pathway Diagram
 Adenine And Adenosine Salvage III Pathway antibodies  Adenine And Adenosine Salvage III Pathway Diagram
Diseases associated with ADA elisa kitOrgans/Tissues associated with ADA elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >575 publications with ADA and Neoplasms
 Nervous System Diseases Antibodies  >412 publications with ADA and Nervous System Diseases
 Brain Diseases Antibodies  >202 publications with ADA and Brain Diseases
 Heart Diseases Antibodies  >180 publications with ADA and Heart Diseases
 Inflammation Antibodies  >160 publications with ADA and Inflammation
 Hypertension Antibodies  >143 publications with ADA and Hypertension
 Necrosis Antibodies  >139 publications with ADA and Necrosis
 Disease Models, Animal Antibodies  >121 publications with ADA and Disease Models, Animal
 Pain Antibodies  >99 publications with ADA and Pain
 Liver Diseases Antibodies  >91 publications with ADA and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2237 publications with ADA and Blood
 Bone Antibodies  >305 publications with ADA and Bone
 Heart Antibodies  >241 publications with ADA and Heart
 Brain Antibodies  >240 publications with ADA and Brain
 Bone Marrow Antibodies  >220 publications with ADA and Bone Marrow
 Lung Antibodies  >207 publications with ADA and Lung
 Liver Antibodies  >199 publications with ADA and Liver
 Spleen Antibodies  >154 publications with ADA and Spleen
 Kidney Antibodies  >145 publications with ADA and Kidney
 Thymus Antibodies  >132 publications with ADA and Thymus
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