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ANG2 elisa kit :: Porcine Angiotensin 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS014613 ANG2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Angiotensin 2 (ANG2), ELISA Kit

★Popular Item★
 Also Known As   

Porcine Angiotensin 2 ELISA Kit

 Product Gene Name   

ANG2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 8; NC_000008.10 (6357172..6420784, complement). Location: 8p23.1
 OMIM    601922
 3D Structure    ModBase 3D Structure for O15123
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 Species Reactivity    Porcine
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Quantitative Sandwich
 Detection Range    15.6pg/ml-500pg/ml
 Sensitivity    2.0pg/ml
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ANG2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ANG2 purchase    MBS014613 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Angiotensin 2 (ANG2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.6pg/ml-500pg/ml in biological research samples containing ANG2, with an estimated sensitivity of 2.0pg/ml. The ELISA analytical biochemical technique of the MBS014613 kit is based on ANG2 antibody-ANG2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ANG2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ANG2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for ANG2 elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ANG2 (hereafter termed "analyte") in undiluted original Porcine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS014613. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ANG2. It may not necessarily be applicable to this product.
 NCBI GI #    169646754
 NCBI GeneID    285
 NCBI Accession #    NP_001112360.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001118888.1 [Other Products]
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 UniProt Primary Accession #    O15123 [Other Products]
 UniProt Secondary Accession #    Q9NRR7; Q9P2Y7; A0AV38; A8K205; B7ZLM7 [Other Products]
 UniProt Related Accession #    O15123 [Other Products]
 Molecular Weight    56,919 Da
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 NCBI Official Full Name    angiopoietin-2 isoform c
 NCBI Official Synonym Full Names    angiopoietin 2
 NCBI Official Symbol    ANGPT2 [Similar Products]
 NCBI Official Synonym Symbols   
ANG2; AGPT2
[Similar Products]
 NCBI Protein Information    angiopoietin-2; ANG-2; Tie2-ligand; angiopoietin-2B; angiopoietin-2a
 UniProt Protein Name    Angiopoietin-2
 Protein Family    Angiogenin
 UniProt Gene Name    ANGPT2 [Similar Products]
 UniProt Synonym Gene Names    ANG-2 [Similar Products]
 UniProt Entry Name    ANGP2_HUMAN
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 NCBI Summary for ANG2    The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ANG2    ANGPT2: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Interacts with TEK/TIE2, competing for the same binding site as ANGPT1. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: extracellular space; cell projection; plasma membrane; extracellular region; nucleus

Molecular Function: protein binding; metal ion binding; receptor tyrosine kinase binding; receptor binding

Biological Process: Tie receptor signaling pathway; organ regeneration; maternal process involved in pregnancy; negative regulation of blood vessel endothelial cell migration; signal transduction; response to organic cyclic substance; germ cell development; negative regulation of positive chemotaxis; positive regulation of angiogenesis; response to radiation; negative regulation of angiogenesis; response to mechanical stimulus; response to hypoxia; response to glucose stimulus; angiogenesis; response to activity; blood coagulation; leukocyte migration
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 Research Articles on ANG2    1. Angiopoietin-2 levels were significantly associated with the development of PGD after lung transplantation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ANG2 elisa kitPathways associated with ANG2 elisa kit
 Reference Product  PubMed Publications
 ANGPT1 elisa kit  >786 publications with ANG2 and ANGPT1
 VEGFA elisa kit  >111 publications with ANG2 and VEGFA
 TEK elisa kit  >37 publications with ANG2 and TEK
 TIE1 elisa kit  >30 publications with ANG2 and TIE1
 FOXO1 elisa kit  >7 publications with ANG2 and FOXO1
 ETS1 elisa kit  >6 publications with ANG2 and ETS1
 CDKN1A elisa kit  >3 publications with ANG2 and CDKN1A
 FYN elisa kit  >3 publications with ANG2 and FYN
 PIK3CA elisa kit  >1 publications with ANG2 and PIK3CA
 Products by Pathway  Pathway Diagram
 Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies  Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 HIF-1 Signaling Pathway antibodies  HIF-1 Signaling Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Tie2 Signaling Pathway antibodies  Tie2 Signaling Pathway Diagram
Diseases associated with ANG2 elisa kitOrgans/Tissues associated with ANG2 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >429 publications with ANG2 and Neoplasms
 Cardiovascular Diseases Antibodies  >223 publications with ANG2 and Cardiovascular Diseases
 Inflammation Antibodies  >185 publications with ANG2 and Inflammation
 Disease Models, Animal Antibodies  >139 publications with ANG2 and Disease Models, Animal
 Necrosis Antibodies  >94 publications with ANG2 and Necrosis
 Neoplasms, Experimental Antibodies  >70 publications with ANG2 and Neoplasms, Experimental
 Heart Diseases Antibodies  >69 publications with ANG2 and Heart Diseases
 Liver Diseases Antibodies  >67 publications with ANG2 and Liver Diseases
 Liver Neoplasms Antibodies  >63 publications with ANG2 and Liver Neoplasms
 Hypertension Antibodies  >57 publications with ANG2 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >1155 publications with ANG2 and Vascular
 Muscle Antibodies  >160 publications with ANG2 and Muscle
 Embryonic Tissue Antibodies  >132 publications with ANG2 and Embryonic Tissue
 Brain Antibodies  >121 publications with ANG2 and Brain
 Lung Antibodies  >114 publications with ANG2 and Lung
 Liver Antibodies  >103 publications with ANG2 and Liver
 Kidney Antibodies  >88 publications with ANG2 and Kidney
 Eye Antibodies  >84 publications with ANG2 and Eye
 Placenta Antibodies  >62 publications with ANG2 and Placenta
 Bone Marrow Antibodies  >54 publications with ANG2 and Bone Marrow
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