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AQP-2 elisa kit :: Porcine Aquaporin 2, Collecting Duct ELISA Kit

Scan QR to view Datasheet Catalog #    MBS016737 AQP-2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Aquaporin 2, Collecting Duct (AQP-2), ELISA Kit

 Also Known As   

Porcine Aquaporin 2, Collecting Duct ELISA Kit

 Product Gene Name   

AQP-2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 12; NC_000012.11 (50344524..50352664). Location: 12q12-q13
 OMIM    107777
 3D Structure    ModBase 3D Structure for P41181
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 Species Reactivity    Porcine
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AQP-2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AQP-2 purchase    MBS016737 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Aquaporin 2, Collecting Duct (AQP-2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AQP-2. The ELISA analytical biochemical technique of the MBS016737 kit is based on AQP-2 antibody-AQP-2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AQP-2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AQP-2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for AQP-2. It may not necessarily be applicable to this product.
 NCBI GI #    4502179
 NCBI GeneID    359
 NCBI Accession #    NP_000477.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000486.5 [Other Products]
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 UniProt Primary Accession #    P41181 [Other Products]
 UniProt Secondary Accession #    Q9UD68 [Other Products]
 UniProt Related Accession #    P41181 [Other Products]
 Molecular Weight    28,837 Da
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 NCBI Official Full Name    aquaporin-2
 NCBI Official Synonym Full Names    aquaporin 2 (collecting duct)
 NCBI Official Symbol    AQP2 [Similar Products]
 NCBI Official Synonym Symbols   
AQP-CD; WCH-CD
[Similar Products]
 NCBI Protein Information    aquaporin-2; AQP-2; aquaporin-CD; ADH water channel; water-channel aquaporin 2; collecting duct water channel protein; water channel protein for renal collecting duct
 UniProt Protein Name    Aquaporin-2
 UniProt Synonym Protein Names   
ADH water channel; Aquaporin-CD; AQP-CD; Collecting duct water channel protein; WCH-CD; Water channel protein for renal collecting duct
 UniProt Gene Name    AQP2 [Similar Products]
 UniProt Synonym Gene Names    AQP-2; AQP-CD [Similar Products]
 UniProt Entry Name    AQP2_HUMAN
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 NCBI Summary for AQP-2    This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 2008]
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 UniProt Comments for AQP-2    AQP2: Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Expressed in renal collecting tubules. Belongs to the MIP/aquaporin (TC 1.A.8) family.

Protein type: Transporter; Membrane protein, multi-pass; Transporter, aquaporin family; Membrane protein, integral; Channel, misc.

Chromosomal Location of Human Ortholog: 12q12-q13

Cellular Component: recycling endosome; protein complex; clathrin-coated vesicle; rough endoplasmic reticulum; membrane; basolateral plasma membrane; integral to plasma membrane; lysosome; early endosome; apical plasma membrane; plasma membrane; trans-Golgi network

Molecular Function: water transporter activity; glycerol transmembrane transporter activity; water channel activity; actin binding; glycerol channel activity; PDZ domain binding

Biological Process: actin filament depolymerization; glycerol transport; cellular water homeostasis; response to glucagon stimulus; apoptosis; water transport; response to lithium ion; cellular response to water deprivation; response to lipopolysaccharide; female pregnancy; excretion; response to salt stress; response to starvation; renal water transport; hyperosmotic response; renal water homeostasis; response to calcium ion; positive regulation of calcium ion transport; transmembrane transport; aging

Disease: Diabetes Insipidus, Nephrogenic, Autosomal
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 Research Articles on AQP-2    1. Together, our data reveal that vasopressin induces instead of reduces the phosphorylation of S261 in AQP2-P262L
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AQP-2 elisa kitPathways associated with AQP-2 elisa kit
 Reference Product  PubMed Publications
 AQP3 elisa kit  >208 publications with AQP-2 and AQP3
 AVP elisa kit  >202 publications with AQP-2 and AVP
 AQP4 elisa kit  >133 publications with AQP-2 and AQP4
 SLC12A1 elisa kit  >3 publications with AQP-2 and SLC12A1
 MYO5B elisa kit  >1 publications with AQP-2 and MYO5B
 Products by Pathway  Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Passive Transport By Aquaporins Pathway antibodies  Passive Transport By Aquaporins Pathway Diagram
 Regulation Of Water Balance By Renal Aquaporins Pathway antibodies  Regulation Of Water Balance By Renal Aquaporins Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Vasopressin-regulated Water Reabsorption Pathway antibodies  Vasopressin-regulated Water Reabsorption Pathway Diagram
 Vasopressin-regulated Water Reabsorption Pathway antibodies  Vasopressin-regulated Water Reabsorption Pathway Diagram
Diseases associated with AQP-2 elisa kitOrgans/Tissues associated with AQP-2 elisa kit
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >314 publications with AQP-2 and Kidney Diseases
 Diabetes Insipidus, Nephrogenic Antibodies  >234 publications with AQP-2 and Diabetes Insipidus, Nephrogenic
 Polyuria Antibodies  >122 publications with AQP-2 and Polyuria
 Cardiovascular Diseases Antibodies  >66 publications with AQP-2 and Cardiovascular Diseases
 Heart Failure Antibodies  >49 publications with AQP-2 and Heart Failure
 Hypertension Antibodies  >44 publications with AQP-2 and Hypertension
 Hyponatremia Antibodies  >42 publications with AQP-2 and Hyponatremia
 Heart Diseases Antibodies  >42 publications with AQP-2 and Heart Diseases
 Brain Diseases Antibodies  >36 publications with AQP-2 and Brain Diseases
 Renal Insufficiency Antibodies  >29 publications with AQP-2 and Renal Insufficiency
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >831 publications with AQP-2 and Kidney
 Brain Antibodies  >72 publications with AQP-2 and Brain
 Eye Antibodies  >25 publications with AQP-2 and Eye
 Testis Antibodies  >9 publications with AQP-2 and Testis
 Prostate Antibodies  >3 publications with AQP-2 and Prostate
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