NP_446337.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
171,815 Da
NCBI Official Full Name
arginine-glutamic acid dipeptide repeats protein
NCBI Official Synonym Full Names
arginine-glutamic acid dipeptide repeats
NCBI Official Synonym Symbols
NCBI Protein Information
arginine-glutamic acid dipeptide repeats protein
UniProt Protein Name
Arginine-glutamic acid dipeptide repeats protein
UniProt Synonym Protein Names
Atrophin-1-related protein
UniProt Synonym Gene Names
NCBI Summary for RERE
atrophin-1 related protein found enriched in cerebellum and testis [RGD, Feb 2006]
UniProt Comments for RERE
RERE: Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. A chromosomal aberration involving RERE is found in the neuroblastoma cell line. Translocation t(1;15)(p36.2;q24). 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor co-regulator; Transcription factor
Chromosomal Location of Human Ortholog: 5q36
Cellular Component: histone deacetylase complex; nucleus; PML body
Molecular Function: chromatin binding; DNA binding transcription factor activity; sequence-specific DNA binding; zinc ion binding
Biological Process: branching morphogenesis of a nerve; cerebellar Purkinje cell layer maturation; cerebellum development; chromatin remodeling; dendrite morphogenesis; granule cell precursor proliferation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; radial glia guided migration of Purkinje cell; transcription, DNA-dependent
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Diseases associated with RERE elisa kit
Organs/Tissues associated with RERE elisa kit
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