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CGRP elisa kit :: Porcine Calcitonin Gene Related Peptide (CGRP) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS269711
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $300 +1 FREE 8GB USB
96-Strip-Wells  /  $475 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Calcitonin Gene Related Peptide (CGRP), ELISA Kit

★Popular Item★
 Also Known As   

Porcine Calcitonin Gene Related Peptide (CGRP) ELISA KIT

 Product Gene Name   

CGRP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    114130
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 Species Reactivity    Porcine
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 Specificity    No cross-reaction with other factors.
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 Samples    Porcine serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant CGRP concentration
 Assay Type    Sandwich
 Detection Range    2000 pg/ml-31.2 pg/ml
 Sensitivity    12 pg/ml.
 Intra-assay Precision    ? 8%
 Inter-assay Precision    ? 12%
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CGRP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CGRP purchase    MBS269711 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Calcitonin Gene Related Peptide (CGRP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 2000 pg/ml-31.2 pg/ml in biological research samples containing CGRP, with an estimated sensitivity of 12 pg/ml. The ELISA analytical biochemical technique of the MBS269711 kit is based on CGRP antibody-CGRP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CGRP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CGRP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Porcine serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant CGRP concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CGRP elisa kit

   Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Porcine CGRP monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Testing Data/Standard Curve (for reference only) of CGRP elisa kit    CGRP elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS269711. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CGRP. It may not necessarily be applicable to this product.
 NCBI GI #    76880478
 NCBI GeneID    796
 NCBI Accession #    NP_001029125.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001033953.2 [Other Products]
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 UniProt Secondary Accession #    Q93048; Q9UCP0 [Other Products]
 UniProt Related Accession #    P01258; P06881 [Other Products]
 Molecular Weight    15,466 Da
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 NCBI Official Full Name    calcitonin gene-related peptide 1 isoform alpha-CGRP preproprotein
 NCBI Official Synonym Full Names    calcitonin-related polypeptide alpha
 NCBI Official Symbol    CALCA [Similar Products]
 NCBI Official Synonym Symbols   
CT; KC; CGRP; CALC1; CGRP1; CGRP-I
[Similar Products]
 NCBI Protein Information    calcitonin; calcitonin gene-related peptide 1; katacalcin; calcitonin 1; alpha-type CGRP; calcitonin gene-related peptide I; calcitonin/calcitonin-related polypeptide, alpha
 UniProt Protein Name    Calcitonin gene-related peptide 1
 UniProt Synonym Protein Names   
Alpha-type CGRP; Calcitonin gene-related peptide I; CGRP-I
 UniProt Gene Name    CALCA [Similar Products]
 UniProt Synonym Gene Names    CALC1; CGRP-I [Similar Products]
 UniProt Entry Name    CALCA_HUMAN
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 NCBI Summary for CGRP    This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]
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 UniProt Comments for CGRP    CALCA iso3: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Belongs to the calcitonin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11p15.2

Cellular Component: extracellular space; cell soma; cytoplasm; extracellular region; terminal button; nucleus

Molecular Function: identical protein binding; protein binding; calcitonin receptor binding; hormone activity; protein complex binding; receptor binding

Biological Process: negative regulation of osteoclast differentiation; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of interleukin-1 alpha production; vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure; response to pain; positive regulation of vasodilation; G-protein signaling, adenylate cyclase activating pathway; protein amino acid phosphorylation; positive regulation of interleukin-8 production; monocyte chemotaxis; elevation of cytosolic calcium ion concentration; leukocyte adhesion; cell-cell signaling; vasculature development; neuropeptide signaling pathway; regulation of blood pressure; negative regulation of smooth muscle contraction; receptor internalization; positive regulation of cAMP biosynthetic process; negative regulation of ossification; feeding behavior; negative regulation of blood pressure; positive regulation of adenylate cyclase activity; detection of temperature stimulus involved in sensory perception of pain; positive regulation of macrophage differentiation; inflammatory response; negative regulation of bone resorption; negative regulation of neurological process; aging; cytosolic calcium ion homeostasis; regulation of heart rate; adenylate cyclase activation; positive regulation of ossification; regulation of systemic arterial blood pressure by neurological process; G-protein coupled receptor internalization; response to heat; endothelial cell proliferation; regulation of inflammatory response; activation of protein kinase activity; endothelial cell migration; negative regulation of transcription, DNA-dependent; embryo implantation
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 Research Articles on CGRP    1. Procalcitonin (PCT) level in blood plasma of patients with bacteremia is higher than in patients with negative blood cultures; Gram-negative infection is more likely in cases when PCT higher than 2.47 ng per ml
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CGRP elisa kitPathways associated with CGRP elisa kit
 Reference Product  PubMed Publications
 RAMP1 elisa kit  >2 publications with CGRP and RAMP1
 POMC elisa kit  >1 publications with CGRP and POMC
 IAPP elisa kit  >1 publications with CGRP and IAPP
 ADM elisa kit  >1 publications with CGRP and ADM
 CALCRL elisa kit  >1 publications with CGRP and CALCRL
 Products by Pathway  Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Calcitonin-like Ligand Receptors Pathway antibodies  Calcitonin-like Ligand Receptors Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Endothelin Pathway antibodies  Endothelin Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
Diseases associated with CGRP elisa kitOrgans/Tissues associated with CGRP elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >11 publications with CGRP and Inflammation
 Hypertension Antibodies  >4 publications with CGRP and Hypertension
 Neurogenic Inflammation Antibodies  >4 publications with CGRP and Neurogenic Inflammation
 Migraine Disorders Antibodies  >4 publications with CGRP and Migraine Disorders
 Headache Antibodies  >4 publications with CGRP and Headache
 Pain Antibodies  >4 publications with CGRP and Pain
 Kidney Diseases Antibodies  >3 publications with CGRP and Kidney Diseases
 Edema Antibodies  >2 publications with CGRP and Edema
 Necrosis Antibodies  >1 publications with CGRP and Necrosis
 Wounds and Injuries Antibodies  >1 publications with CGRP and Wounds and Injuries
 Organ/Tissue Name  Pubmed Publications
 Thyroid Antibodies  >11 publications with CGRP and Thyroid
 Brain Antibodies  >7 publications with CGRP and Brain
 Mixed Antibodies  >1 publications with CGRP and Mixed
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