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| Product Name
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Cardiac Troponin T (CTNT), ELISA Kit ★Popular Item★
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| Also Known As
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Porcine Cardiac Troponin T ELISA Kit
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| Product Gene Name
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[Similar Products]
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| Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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| Sample Manual Insert
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| Request for Current Manual Insert
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| Chromosome Location
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Chromosome: 1; NC_000001.10 (201328142..201346805, complement). Location: 1q32
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| OMIM
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115195
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| 3D Structure
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ModBase 3D Structure for P45379
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| Species Reactivity
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Porcine
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| Specificity
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No significant cross-reactivity or interference between this analyte and analogues is observed.
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| Samples
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Undiluted original Porcine body fluids, tissue homogenates, secretions or feces samples.
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| Assay Type
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Sandwich
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| Detection Range
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31.2 pg/ml - 1000 pg/ml.
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| Sensitivity
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5.0 pg/ml.
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| Intra-assay Precision
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Intra-assay CV (%) is less than 15%.
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| Inter-assay Precision
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Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
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| Preparation and Storage
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Store all reagents at 2-8 degree C
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| Product Note
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Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
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| Other Notes
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Small volumes of CTNT elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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| Searchable Terms for CTNT purchase
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MBS041411 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cardiac Troponin T (CTNT) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.2 pg/ml - 1000 pg/ml in biological research samples containing CTNT, with an estimated sensitivity of 5.0 pg/ml. The ELISA analytical biochemical technique of the MBS041411 kit is based on CTNT antibody-CTNT antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CTNT antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CTNT. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Undiluted original Porcine body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CTNT elisa kit
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Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CTNT (hereafter termed "analyte") in undiluted original Porcine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
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| Sample Manual Insert of MBS041411. Click to request current manual
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| NCBI/Uniprot data below describe general gene information for CTNT. It may not necessarily be applicable to this product. |
| NCBI GI #
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15290516
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| NCBI GeneID
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7139
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| NCBI Accession #
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AAK92231.1
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[Other Products]
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| UniProt Primary Accession #
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P45379
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[Other Products]
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| UniProt Secondary Accession #
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O60214; Q99596; Q99597; Q9BUF6; Q9UM96; A2TDB9; A8K3K6
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[Other Products]
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| UniProt Related Accession #
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P45379
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[Other Products]
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| Molecular Weight
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35,924 Da
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| NCBI Official Full Name
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cardiac troponin T
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| NCBI Official Synonym Full Names
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troponin T type 2 (cardiac)
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| NCBI Official Symbol
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TNNT2
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[Similar Products]
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| NCBI Official Synonym Symbols
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CMH2; RCM3; TnTC; cTnT; CMPD2; LVNC6
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[Similar Products]
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| NCBI Protein Information
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troponin T, cardiac muscle; troponin T2, cardiac; cardiomyopathy, hypertrophic 2; cardiomyopathy, dilated 1D (autosomal dominant)
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| UniProt Protein Name
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Troponin T, cardiac muscle
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| UniProt Synonym Protein Names
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Cardiac muscle troponin T
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| UniProt Gene Name
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TNNT2
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[Similar Products]
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| UniProt Synonym Gene Names
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TnTc; cTnT
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[Similar Products]
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| UniProt Entry Name
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TNNT2_HUMAN
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| NCBI Summary for CTNT
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The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
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| UniProt Comments for CTNT
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TNNT2: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart. Belongs to the troponin T family. 11 isoforms of the human protein are produced by alternative splicing.
Protein type: Motor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1q32
Cellular Component: sarcomere; troponin complex; cytosol; striated muscle thin filament
Molecular Function: troponin C binding; structural constituent of cytoskeleton; troponin I binding; ATPase activity; actin binding; tropomyosin binding
Biological Process: atrial cardiac muscle morphogenesis; positive regulation of ATPase activity; metabolic process; regulation of muscle contraction; ventricular cardiac muscle morphogenesis; sarcomere organization; response to calcium ion; negative regulation of ATPase activity; regulation of heart contraction; muscle filament sliding
Disease: Cardiomyopathy, Familial Restrictive, 3; Cardiomyopathy, Dilated, 1d; Cardiomyopathy, Familial Hypertrophic, 2
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| Research Articles on CTNT
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1. Using the novel hsTnT assay, the current study provides first evidence that hsTnT levels increase in pulmonary arterial hypertension patients after maximal physical exercise.
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| Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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| Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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| Products associated with CTNT elisa kit | Pathways associated with CTNT elisa kit |
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| Diseases associated with CTNT elisa kit | Organs/Tissues associated with CTNT elisa kit |
| Disease Name |
Pubmed Publications |
| Heart Diseases Antibodies |
>126 publications with CTNT and Heart Diseases |
| Cardiovascular Diseases Antibodies |
>126 publications with CTNT and Cardiovascular Diseases |
| Cardiomyopathies Antibodies |
>100 publications with CTNT and Cardiomyopathies |
| Cardiomyopathy, Hypertrophic Antibodies |
>94 publications with CTNT and Cardiomyopathy, Hypertrophic |
| Cardiomyopathy, Hypertrophic, Familial Antibodies |
>46 publications with CTNT and Cardiomyopathy, Hypertrophic, Familial |
| Cardiomyopathy, Dilated Antibodies |
>37 publications with CTNT and Cardiomyopathy, Dilated |
| Hypertrophy Antibodies |
>36 publications with CTNT and Hypertrophy |
| Cardiomyopathy, Familial Hypertrophic, 2 Antibodies |
>28 publications with CTNT and Cardiomyopathy, Familial Hypertrophic, 2 |
| Heart Failure Antibodies |
>27 publications with CTNT and Heart Failure |
| Myocardial Ischemia Antibodies |
>12 publications with CTNT and Myocardial Ischemia |
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ELISA Kit 
