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CASPASE-6 elisa kit :: Porcine Caspase 6 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS010752 CASPASE-6 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Caspase 6 (CASPASE-6), ELISA Kit

 Also Known As   

Porcine Caspase 6 ELISA Kit

 Product Gene Name   

CASPASE-6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 3; NC_000069.6 (129901425..129914102). Location: 3; 3 H1
 3D Structure    ModBase 3D Structure for O08738
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 Species Reactivity    Porcine
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CASPASE-6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CASPASE-6 purchase    MBS010752 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Caspase 6 (CASPASE-6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CASPASE-6. The ELISA analytical biochemical technique of the MBS010752 kit is based on CASPASE-6 antibody-CASPASE-6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CASPASE-6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CASPASE-6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CASPASE-6. It may not necessarily be applicable to this product.
 NCBI GI #    157951736
 NCBI GeneID    12368
 NCBI Accession #    NP_033941.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_009811.3 [Other Products]
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 UniProt Primary Accession #    O08738 [Other Products]
 UniProt Related Accession #    O08738 [Other Products]
 Molecular Weight    31,595 Da
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 NCBI Official Full Name    caspase-6
 NCBI Official Synonym Full Names    caspase 6
 NCBI Official Symbol    Casp6 [Similar Products]
 NCBI Official Synonym Symbols   
Mch2; mCASP-6
[Similar Products]
 NCBI Protein Information    caspase-6; CASP-6; apoptotic protease Mch-2
 UniProt Protein Name    Caspase-6
 UniProt Synonym Protein Names   
Apoptotic protease Mch-2
 UniProt Gene Name    Casp6 [Similar Products]
 UniProt Synonym Gene Names    CASP-6 [Similar Products]
 UniProt Entry Name    CASP6_MOUSE
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 NCBI Summary for CASPASE-6    This gene encodes a member of the cysteine proteases that plays important roles in regulating apoptosis and neurodegeneration. The encoded protein is involved in the transmission of pain and axonal degeneration. Genetic deletion of this gene in mice results in the delay of axon pruning and protects from axon degeneration. [provided by RefSeq, Apr 2015]
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 UniProt Comments for CASPASE-6    CASP6: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (p18) and a 11 kDa (p11) subunit. Interacts with BIRC6/bruce. Activation is suppressed by phosphorylation at Ser-257. Belongs to the peptidase C14A family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.22.59; Apoptosis; Protease

Cellular Component: nucleoplasm; cytoplasm; cytosol; nucleus

Molecular Function: peptidase activity; identical protein binding; protein binding; hydrolase activity; endopeptidase activity; cysteine-type peptidase activity

Biological Process: regulation of apoptosis; response to hydrogen peroxide; positive regulation of apoptosis; positive regulation of retinal cell programmed cell death; response to cytokine stimulus; positive regulation of neuron apoptosis; acute inflammatory response to non-antigenic stimulus; response to glucose stimulus; proteolysis; response to iron ion
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 Research Articles on CASPASE-6    1. both Caspase-3 and Caspase-6 are implicated in axon degeneration that occurs as a part of normal development.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CASPASE-6 elisa kitDiseases associated with CASPASE-6 elisa kit
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Modulation By HSP70 Pathway antibodies  Apoptosis Modulation By HSP70 Pathway Diagram
 Apoptosis Signaling Pathway antibodies  Apoptosis Signaling Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Breakdown Of The Nuclear Lamina Pathway antibodies  Breakdown Of The Nuclear Lamina Pathway Diagram
 Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway antibodies  Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >179 publications with CASPASE-6 and Neoplasms
 Necrosis Antibodies  >77 publications with CASPASE-6 and Necrosis
 Nervous System Diseases Antibodies  >72 publications with CASPASE-6 and Nervous System Diseases
 Drug Toxicity Antibodies  >41 publications with CASPASE-6 and Drug Toxicity
 Disease Models, Animal Antibodies  >34 publications with CASPASE-6 and Disease Models, Animal
 Breast Neoplasms Antibodies  >32 publications with CASPASE-6 and Breast Neoplasms
 Adenocarcinoma Antibodies  >27 publications with CASPASE-6 and Adenocarcinoma
 Inflammation Antibodies  >22 publications with CASPASE-6 and Inflammation
 Nerve Degeneration Antibodies  >20 publications with CASPASE-6 and Nerve Degeneration
 Cognition Disorders Antibodies  >18 publications with CASPASE-6 and Cognition Disorders
Organs/Tissues associated with CASPASE-6 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >71 publications with CASPASE-6 and Brain
 Liver Antibodies  >30 publications with CASPASE-6 and Liver
 Lung Antibodies  >26 publications with CASPASE-6 and Lung
 Skin Antibodies  >21 publications with CASPASE-6 and Skin
 Muscle Antibodies  >21 publications with CASPASE-6 and Muscle
 Kidney Antibodies  >21 publications with CASPASE-6 and Kidney
 Prostate Antibodies  >17 publications with CASPASE-6 and Prostate
 Embryonic Tissue Antibodies  >15 publications with CASPASE-6 and Embryonic Tissue
 Eye Antibodies  >14 publications with CASPASE-6 and Eye
 Bone Antibodies  >14 publications with CASPASE-6 and Bone
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