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CFHR5 elisa kit :: Porcine Complement factor H-related protein 5 (CFHR5) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7205211 CFHR5 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Complement factor H-related protein 5 (CFHR5), ELISA Kit

 Also Known As   

Porcine Complement factor H-related protein 5 (CFHR5) ELISA Kit

 Product Gene Name   

CFHR5 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 614809
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 Species Reactivity    Porcine
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CFHR5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CFHR5 purchase    MBS7205211 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Complement factor H-related protein 5 (CFHR5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CFHR5. The ELISA analytical biochemical technique of the MBS7205211 kit is based on CFHR5 antibody-CFHR5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CFHR5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CFHR5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CFHR5 elisa kit    Immunology
NCBI/Uniprot data below describe general gene information for CFHR5. It may not necessarily be applicable to this product.
 NCBI GI #    13540563
 NCBI GeneID    81494
 NCBI Accession #    NP_110414.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_030787.3 [Other Products]
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 UniProt Secondary Accession #    Q2NKK2 [Other Products]
 UniProt Related Accession #    Q9BXR6 [Other Products]
 Molecular Weight    64,419 Da
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 NCBI Official Full Name    complement factor H-related protein 5
 NCBI Official Synonym Full Names    complement factor H-related 5
 NCBI Official Symbol    CFHR5 [Similar Products]
 NCBI Official Synonym Symbols   
FHR5; CFHL5; FHR-5; CFHR5D
[Similar Products]
 NCBI Protein Information    complement factor H-related protein 5
 UniProt Protein Name    Complement factor H-related protein 5
 Protein Family    Complement factor H-related protein
 UniProt Gene Name    CFHR5 [Similar Products]
 UniProt Synonym Gene Names    CFHL5; FHR5; FHR-5 [Similar Products]
 UniProt Entry Name    FHR5_HUMAN
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 NCBI Summary for CFHR5    This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010]
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 UniProt Comments for CFHR5    CFHR5: Involved in complement regulation. Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. Atypical hemolytic uremic syndrome is a complex genetic disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and absence of episodes of enterocolitis and diarrhea. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease. Susceptibility to the development of atypical hemolytic uremic syndrome can be conferred by mutations in various components of or regulatory factors in the complement cascade system. Other genes may play a role in modifying the phenotype.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1q31.3

Cellular Component: extracellular region

Biological Process: complement activation, alternative pathway

Disease: Cfhr5 Deficiency
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 Research Articles on CFHR5    1. A hybrid CFHR2-CFHR5 plasma protein, arising from a chromosomal deletion mutation stabilizes the C3 convertase and reduces factor H-mediated convertase decay.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CFHR5 elisa kitDiseases associated with CFHR5 elisa kit
 Reference Product  PubMed Publications
 CFI elisa kit  >5 publications with CFHR5 and CFI
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >5 publications with CFHR5 and Inflammation
 Edema Antibodies  >1 publications with CFHR5 and Edema
 Atrophy Antibodies  >1 publications with CFHR5 and Atrophy
 Urogenital Abnormalities Antibodies  >1 publications with CFHR5 and Urogenital Abnormalities
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