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B7-H4 elisa kit :: Porcine Costimulatory Molecules B7H4 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS027379 B7-H4 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Costimulatory Molecules B7H4 (B7-H4), ELISA Kit

 Also Known As   

Porcine Costimulatory Molecules B7H4 ELISA Kit

 Product Gene Name   

B7-H4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 1; NC_000001.10 (117686209..117753582, complement). Location: 1p13.1
 OMIM    608162
 3D Structure    ModBase 3D Structure for Q7Z7D3
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 Species Reactivity    Porcine
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of B7-H4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for B7-H4 purchase    MBS027379 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Costimulatory Molecules B7H4 (B7-H4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing B7-H4. The ELISA analytical biochemical technique of the MBS027379 kit is based on B7-H4 antibody-B7-H4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect B7-H4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, B7-H4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for B7-H4. It may not necessarily be applicable to this product.
 NCBI GI #    70997756
 NCBI GeneID    79679
 NCBI Accession #    AAZ17406.1 [Other Products]
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 UniProt Primary Accession #    Q7Z7D3 [Other Products]
 UniProt Secondary Accession #    Q0GN76; Q45VN0; Q5WPZ3; Q6P097; Q9H6B2 [Other Products]
 UniProt Related Accession #    Q7Z7D3 [Other Products]
 Molecular Weight    30,878 Da
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 NCBI Official Full Name    B7-H4
 NCBI Official Synonym Full Names    V-set domain containing T cell activation inhibitor 1
 NCBI Official Symbol    VTCN1 [Similar Products]
 NCBI Official Synonym Symbols   
B7X; B7H4; B7S1; B7-H4; B7h.5; VCTN1; PRO1291; RP11-229A19.4
[Similar Products]
 NCBI Protein Information    V-set domain-containing T-cell activation inhibitor 1; B7 family member, H4; B7 superfamily member 1; T cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; immune costimulatory protein B7-H4
 UniProt Protein Name    V-set domain-containing T-cell activation inhibitor 1
 UniProt Synonym Protein Names   
B7h.5; Immune costimulatory protein B7-H4; Protein B7S1; T-cell costimulatory molecule B7x
 UniProt Gene Name    VTCN1 [Similar Products]
 UniProt Synonym Gene Names    B7H4 [Similar Products]
 UniProt Entry Name    VTCN1_HUMAN
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 NCBI Summary for B7-H4    This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
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 UniProt Comments for B7-H4    VTCN1: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor- associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.1

Cellular Component: integral to membrane; external side of plasma membrane

Molecular Function: receptor binding

Biological Process: response to protozoan; immune system process; positive regulation of T cell proliferation; negative regulation of T cell activation
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 Research Articles on B7-H4    1. B7-H4 expression in malignant tumors is useful for clinical diagnosis, and may provide a novel molecular target for cancer treatment.[review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with B7-H4 elisa kitPathways associated with B7-H4 elisa kit
 Reference Product  PubMed Publications
 CTLA4 elisa kit  >7 publications with B7-H4 and CTLA4
 BTLA elisa kit  >3 publications with B7-H4 and BTLA
 PDCD1 elisa kit  >1 publications with B7-H4 and PDCD1
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
Diseases associated with B7-H4 elisa kitOrgans/Tissues associated with B7-H4 elisa kit
 Disease Name  Pubmed Publications
 Ovarian Diseases Antibodies  >16 publications with B7-H4 and Ovarian Diseases
 Ovarian Neoplasms Antibodies  >16 publications with B7-H4 and Ovarian Neoplasms
 Disease Models, Animal Antibodies  >8 publications with B7-H4 and Disease Models, Animal
 Adenocarcinoma Antibodies  >8 publications with B7-H4 and Adenocarcinoma
 Necrosis Antibodies  >6 publications with B7-H4 and Necrosis
 Kidney Diseases Antibodies  >4 publications with B7-H4 and Kidney Diseases
 Endometrial Neoplasms Antibodies  >2 publications with B7-H4 and Endometrial Neoplasms
 Encephalomyelitis, Autoimmune, Experimental Antibodies  >2 publications with B7-H4 and Encephalomyelitis, Autoimmune, Experimental
 Prostatic Diseases Antibodies  >2 publications with B7-H4 and Prostatic Diseases
 Hyperplasia Antibodies  >1 publications with B7-H4 and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >9 publications with B7-H4 and Lung
 Pancreas Antibodies  >7 publications with B7-H4 and Pancreas
 Kidney Antibodies  >5 publications with B7-H4 and Kidney
 Liver Antibodies  >4 publications with B7-H4 and Liver
 Bone Antibodies  >3 publications with B7-H4 and Bone
 Ovary Antibodies  >3 publications with B7-H4 and Ovary
 Uterus Antibodies  >3 publications with B7-H4 and Uterus
 Prostate Antibodies  >2 publications with B7-H4 and Prostate
 Placenta Antibodies  >1 publications with B7-H4 and Placenta
 Embryonic Tissue Antibodies  >1 publications with B7-H4 and Embryonic Tissue
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