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CNGB1 elisa kit :: Porcine Cyclic nucleotide-gated cation channel beta-1 (CNGB1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7204664 CNGB1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cyclic nucleotide-gated cation channel beta-1 (CNGB1), ELISA Kit

 Also Known As   

Porcine Cyclic nucleotide-gated cation channel beta-1 (CNGB1) ELISA Kit

 Product Gene Name   

CNGB1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 613767
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 Species Reactivity    Porcine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CNGB1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CNGB1 purchase    MBS7204664 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cyclic nucleotide-gated cation channel beta-1 (CNGB1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CNGB1. The ELISA analytical biochemical technique of the MBS7204664 kit is based on CNGB1 antibody-CNGB1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CNGB1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CNGB1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CNGB1 elisa kit    Neurobiology
NCBI/Uniprot data below describe general gene information for CNGB1. It may not necessarily be applicable to this product.
 NCBI GI #    554790418
 NCBI GeneID    1258
 NCBI Accession #    NP_001273059.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001286130.1 [Other Products]
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 UniProt Secondary Accession #    O43636; Q13059; Q14029; Q9UMG2; H3BN09 [Other Products]
 UniProt Related Accession #    Q14028; AAB32607 [Other Products]
 Molecular Weight    139,179 Da
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 NCBI Official Full Name    cyclic nucleotide-gated cation channel beta-1 isoform c
 NCBI Official Synonym Full Names    cyclic nucleotide gated channel beta 1
 NCBI Official Symbol    CNGB1 [Similar Products]
 NCBI Official Synonym Symbols   
CNG4; GAR1; GARP; RP45; CNCG2; CNCG4; GARP2; RCNC2; RCNCb; CNCG3L; CNGB1B; RCNCbeta
[Similar Products]
 NCBI Protein Information    cyclic nucleotide-gated cation channel beta-1; CNG-4; CNG channel beta-1; glutamic acid-rich protein; glutamic-acid-rich protein; cyclic nucleotide-gated channel beta-1; cyclic nucleotide-gated cation channel 4; cyclic nucleotide-gated cation channel gamma; cyclic nucleotide-gated cation channel modulatory subunit
 UniProt Protein Name    Cyclic nucleotide-gated cation channel beta-1
 UniProt Synonym Protein Names   
Cyclic nucleotide-gated cation channel 4; CNG channel 4; CNG-4; CNG4; Cyclic nucleotide-gated cation channel gamma; Cyclic nucleotide-gated cation channel modulatory subunit; Cyclic nucleotide-gated channel beta-1; CNG channel beta-1; Glutamic acid-rich protein; GARP
 Protein Family    Cyclic nucleotide-gated cation channel
 UniProt Gene Name    CNGB1 [Similar Products]
 UniProt Synonym Gene Names    CNCG2; CNCG3L; CNCG4; RCNC2; CNG channel 4; CNG-4; CNG4; CNG channel beta-1; GARP [Similar Products]
 UniProt Entry Name    CNGB1_HUMAN
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 NCBI Summary for CNGB1    In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
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 UniProt Comments for CNGB1    CNGB1: an integral membrane protein that forms a heterooligomeric complex with CNGA1. A modulatory subunit of cyclic nucleotide-gated cation channels.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, cation

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: Golgi membrane; integral to plasma membrane; plasma membrane; intracellular cyclic nucleotide activated cation channel complex; terminal button

Molecular Function: protein binding; voltage-gated potassium channel activity; intracellular cAMP activated cation channel activity; intracellular cGMP activated cation channel activity; cGMP binding; cAMP binding; ligand-gated ion channel activity

Biological Process: phototransduction, visible light; cytosolic calcium ion homeostasis; organelle organization and biogenesis; photoreceptor cell maintenance; sensory perception of smell; rhodopsin mediated signaling; retinal homeostasis; regulation of membrane potential; regulation of rhodopsin mediated signaling; visual perception; transport; protein localization in organelle; detection of light stimulus involved in visual perception; protein heterotetramerization; cation transport

Disease: Retinitis Pigmentosa 45
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 Research Articles on CNGB1    1. The p.Arg86Gln mutation actually appears to be a polymorphism common in ethnic West Africans and not associated with RP. This change may provide a useful marker for West African ancestry.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CNGB1 elisa kitPathways associated with CNGB1 elisa kit
 Reference Product  PubMed Publications
 PDE6B elisa kit  >5 publications with CNGB1 and PDE6B
 ABCA4 elisa kit  >3 publications with CNGB1 and ABCA4
 CNGA2 elisa kit  >3 publications with CNGB1 and CNGA2
 PDE6A elisa kit  >2 publications with CNGB1 and PDE6A
 PRPH2 elisa kit  >1 publications with CNGB1 and PRPH2
 Products by Pathway  Pathway Diagram
 Activation Of The Phototransduction Cascade Pathway antibodies  Activation Of The Phototransduction Cascade Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 Inactivation, Recovery And Regulation Of The Phototransduction Cascade Pathway antibodies  Inactivation, Recovery And Regulation Of The Phototransduction Cascade Pathway Diagram
 Olfactory Transduction Pathway antibodies  Olfactory Transduction Pathway Diagram
 Olfactory Transduction Pathway antibodies  Olfactory Transduction Pathway Diagram
 Phototransduction Pathway antibodies  Phototransduction Pathway Diagram
 Phototransduction Pathway antibodies  Phototransduction Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 The Phototransduction Cascade Pathway antibodies  The Phototransduction Cascade Pathway Diagram
Diseases associated with CNGB1 elisa kitOrgans/Tissues associated with CNGB1 elisa kit
 Disease Name  Pubmed Publications
 Eye Diseases Antibodies  >20 publications with CNGB1 and Eye Diseases
 Retinitis Pigmentosa Antibodies  >19 publications with CNGB1 and Retinitis Pigmentosa
 Disease Models, Animal Antibodies  >7 publications with CNGB1 and Disease Models, Animal
 Nerve Degeneration Antibodies  >6 publications with CNGB1 and Nerve Degeneration
 Nervous System Diseases Antibodies  >5 publications with CNGB1 and Nervous System Diseases
 Brain Diseases Antibodies  >1 publications with CNGB1 and Brain Diseases
 Weight Loss Antibodies  >1 publications with CNGB1 and Weight Loss
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >35 publications with CNGB1 and Eye
 Brain Antibodies  >6 publications with CNGB1 and Brain
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