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Fbn elisa kit :: Porcine Fbn ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2506852 Fbn elisa kit
Unit / Price
48-Strip-Wells  /  $450 +1 FREE 8GB USB
96-Strip-Wells  /  $535 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,255 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fbn, ELISA Kit

 Also Known As   

Porcine Fbn (Fibrinolysin) ELISA Kit

 Product Gene Name   

Fbn elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 OMIM    102370
 3D Structure    ModBase 3D Structure for P35555
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 Species Reactivity    Porcine
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 Specificity    This kit recognizes natural and recombinant Porcine Fbn. No significant cross-reactivity or interference between Porcine Fbn and analogues was observed.
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 Samples    Serum, plasma and other biological fluids
 Assay Type    Quantitative Sandwich
 Detection Range    0.313-20ng/mL
 Sensitivity    0.188ng/mL
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 Preparation and Storage    Store at 4 degree C.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of Fbn elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Fbn purchase    MBS2506852 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fbn, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.313-20ng/mL in biological research samples containing Fbn, with an estimated sensitivity of 0.188ng/mL. The ELISA analytical biochemical technique of the MBS2506852 kit is based on Fbn antibody-Fbn antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Fbn antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Fbn. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for Fbn elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Porcine Fbn concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Fbn. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Fbn and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Fbn, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Fbn. You can calculate the concentration of Fbn in the samples by comparing the OD of the samples to the standard curve.
Sample Manual Insert of MBS2506852
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NCBI/Uniprot data below describe general gene information for Fbn. It may not necessarily be applicable to this product.
 NCBI GI #    281485550
 NCBI GeneID    2200
 NCBI Accession #    NP_000129.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_000138.4 [Other Products]
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 UniProt Primary Accession #    P35555 [Other Products]
 UniProt Secondary Accession #    Q15972; Q75N87; B2RUU0; D2JYH6 [Other Products]
 UniProt Related Accession #    P35555 [Other Products]
 Molecular Weight    312,237 Da
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 NCBI Official Full Name    fibrillin-1
 NCBI Official Synonym Full Names    fibrillin 1
 NCBI Official Symbol    FBN1 [Similar Products]
 NCBI Official Synonym Symbols   
FBN; SGS; WMS; MASS; MFS1; OCTD; SSKS; WMS2; ACMICD; ECTOL1; GPHYSD2
[Similar Products]
 NCBI Protein Information    fibrillin-1; fibrillin 15
 UniProt Protein Name    Fibrillin-1
 UniProt Gene Name    FBN1 [Similar Products]
 UniProt Synonym Gene Names    FBN [Similar Products]
 UniProt Entry Name    FBN1_HUMAN
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 NCBI Summary for Fbn    This gene encodes a member of the fibrillin family. The encoded protein is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome. [provided by RefSeq, Jul 2008]
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 UniProt Comments for Fbn    FBN1: a large, extracellular matrix glycoprotein of the fibrillin family that serves as a structural component of 10-12 nm calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1- containing microfibrils provide long-term force bearing structural support in elastic and nonelastic connective tissue throughout the body. May regulate osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively. Defects in this protein are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome. Interacts with COL16A1.

Protein type: Secreted, signal peptide; Secreted; Extracellular matrix

Chromosomal Location of Human Ortholog: 15q21.1

Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; extracellular region; microfibril; basement membrane

Molecular Function: protein binding; extracellular matrix structural constituent; calcium ion binding

Biological Process: extracellular matrix disassembly; extracellular matrix organization and biogenesis; heart development; metanephros development; skeletal development

Disease: Ectopia Lentis 1, Isolated, Autosomal Dominant; Mass Syndrome; Weill-marchesani Syndrome 2; Stiff Skin Syndrome; Acromicric Dysplasia; Marfan Syndrome; Geleophysic Dysplasia 2
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 Research Articles on Fbn    1. Identification of single nucleotide polymorphisms of FBN1 gene that are associated with essential hypertension in Han Chinese population.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Porcine Fbn (Fibrinolysin) ELISA Kit
 Catalog #  Product Name  Catalog #  Product Name
 MBS2503597  Chicken FBN3 (Fibrillin 3) ELISA Kit  MBS2515275  Rabbit FBN2 (Fibrillin 2) ELISA Kit
 MBS245640  Mouse Monoclonal [clone 3H6] (IgG2a,k) to Human FBN1 / Fibrillin 1  MBS2044721  APC-Linked Polyclonal Antibody to Fibrillin 1 (FBN1)
 MBS2505923  Chicken FBN1 (Fibrillin 1) ELISA Kit  MBS2044694  APC-Linked Polyclonal Antibody to Fibrillin 1 (FBN1)
 MBS2044727  FITC-Linked Polyclonal Antibody to Fibrillin 1 (FBN1)  MBS2044700  Cy3-Linked Polyclonal Antibody to Fibrillin 1 (FBN1)
 MBS2010376  Recombinant Fibrillin 1 (FBN1)  MBS2044742  Cy3-Linked Polyclonal Antibody to Fibrillin 1 (FBN1)
Products associated with Fbn elisa kitPathways associated with Fbn elisa kit
 Reference Product  PubMed Publications
 DCN elisa kit  >4 publications with Fbn and DCN
 ELN elisa kit  >4 publications with Fbn and ELN
 FBLN2 elisa kit  >2 publications with Fbn and FBLN2
 ITGA5 elisa kit  >1 publications with Fbn and ITGA5
 ITGB6 elisa kit  >1 publications with Fbn and ITGB6
 ITGAV elisa kit  >1 publications with Fbn and ITGAV
 MFAP5 elisa kit  >1 publications with Fbn and MFAP5
 Products by Pathway  Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Integrin Cell Surface Interactions Pathway antibodies  Integrin Cell Surface Interactions Pathway Diagram
Diseases associated with Fbn elisa kitOrgans/Tissues associated with Fbn elisa kit
 Disease Name  Pubmed Publications
 Marfan Syndrome Antibodies  >470 publications with Fbn and Marfan Syndrome
 Cardiovascular Diseases Antibodies  >411 publications with Fbn and Cardiovascular Diseases
 Heart Diseases Antibodies  >387 publications with Fbn and Heart Diseases
 Ectopia Lentis Antibodies  >93 publications with Fbn and Ectopia Lentis
 Aortic Aneurysm, Thoracic Antibodies  >61 publications with Fbn and Aortic Aneurysm, Thoracic
 Disease Models, Animal Antibodies  >41 publications with Fbn and Disease Models, Animal
 Arachnodactyly Antibodies  >35 publications with Fbn and Arachnodactyly
 Aortic Rupture Antibodies  >25 publications with Fbn and Aortic Rupture
 Nervous System Diseases Antibodies  >20 publications with Fbn and Nervous System Diseases
 Weill-Marchesani Syndrome Antibodies  >17 publications with Fbn and Weill-Marchesani Syndrome
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >217 publications with Fbn and Connective Tissue
 Vascular Antibodies  >88 publications with Fbn and Vascular
 Heart Antibodies  >66 publications with Fbn and Heart
 Skin Antibodies  >63 publications with Fbn and Skin
 Eye Antibodies  >42 publications with Fbn and Eye
 Bone Antibodies  >40 publications with Fbn and Bone
 Muscle Antibodies  >40 publications with Fbn and Muscle
 Lung Antibodies  >18 publications with Fbn and Lung
 Embryonic Tissue Antibodies  >14 publications with Fbn and Embryonic Tissue
 Kidney Antibodies  >10 publications with Fbn and Kidney
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