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GPR48 elisa kit :: Porcine G Protein Coupled Receptor 48 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS746982 GPR48 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

G Protein Coupled Receptor 48 (GPR48), ELISA Kit

 Also Known As   

Porcine G Protein Coupled Receptor 48 ELISA Kit

 Product Gene Name   

GPR48 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    gene 615311
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 Species Reactivity    Porcine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact technical support.
 Other Notes    Small volumes of GPR48 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GPR48 purchase    MBS746982 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the G Protein Coupled Receptor 48 (GPR48) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GPR48. The ELISA analytical biochemical technique of the MBS746982 kit is based on GPR48 antibody-GPR48 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GPR48 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GPR48. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for GPR48 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for GPR48. It may not necessarily be applicable to this product.
 NCBI GI #    7739737
 NCBI GeneID    55366
 NCBI Accession #    AAF68989.1 [Other Products]
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 UniProt Secondary Accession #    Q8N537; Q9NYD1; A6NCH3; G5E9B3 [Other Products]
 UniProt Related Accession #    Q9BXB1 [Other Products]
 Molecular Weight    101,667 Da
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 NCBI Official Full Name    G-protein-coupled receptor 48
 NCBI Official Synonym Full Names    leucine-rich repeat containing G protein-coupled receptor 4
 NCBI Official Symbol    LGR4 [Similar Products]
 NCBI Official Synonym Symbols   
GPR48; BNMD17
[Similar Products]
 NCBI Protein Information    leucine-rich repeat-containing G-protein coupled receptor 4; G protein-coupled receptor 48
 UniProt Protein Name    Leucine-rich repeat-containing G-protein coupled receptor 4
 UniProt Synonym Protein Names   
G-protein coupled receptor 48
 UniProt Gene Name    LGR4 [Similar Products]
 UniProt Synonym Gene Names    GPR48 [Similar Products]
 UniProt Entry Name    LGR4_HUMAN
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 NCBI Summary for GPR48    G protein-coupled receptors (GPCRs) play key roles in a variety of physiologic functions. Members of the leucine-rich GPCR (LGR) family, such as GPR48, have multiple N-terminal leucine-rich repeats (LRRs) and a 7-transmembrane domain (Weng et al., 2008 [PubMed 18424556]).[supplied by OMIM, Aug 2008]
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 UniProt Comments for GPR48    LGR4: a leucine-rich repeat-containing G-protein-coupled receptor. Receptor for R-spondins, potent stimulators of adult stem cell proliferation. A Wnt receptor component that enhances Wnt signaling by soluble R-spondin proteins. Plays an essential role during homeostasis of the adult mouse intestine.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 11p14-p13

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding; transmembrane receptor activity

Biological Process: positive regulation of transcription, DNA-dependent; negative regulation of cytokine secretion; bone remodeling; bone mineralization; osteoblast differentiation; G-protein coupled receptor protein signaling pathway; epithelial cell proliferation; male genitalia development; negative regulation of toll-like receptor signaling pathway; innate immune response; spermatogenesis; circadian regulation of gene expression; negative regulation of transcription, DNA-dependent

Disease: Bone Mineral Density Quantitative Trait Locus 17
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 Research Articles on GPR48    1. our results suggest a previously unknown Stat3-LGR4 molecular network, which may control osteosarcoma development and progression
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Porcine G Protein Coupled Receptor 48 ELISA Kit
 Catalog #  Product Name  Catalog #  Product Name
 MBS751818  Guinea pig G Protein Coupled Receptor 48 ELISA Kit  MBS744408  Mouse G Protein Coupled Receptor 48 ELISA Kit
 MBS750921  Chicken G Protein Coupled Receptor 48 ELISA Kit  MBS723237  Human G Protein Coupled Receptor 48 ELISA Kit
 MBS745735  Sheep G Protein Coupled Receptor 48 ELISA Kit  MBS750010  Monkey G Protein Coupled Receptor 48 ELISA Kit
 MBS745182  Canine G Protein Coupled Receptor 48 ELISA Kit  MBS746982  Porcine G Protein Coupled Receptor 48 ELISA Kit
 MBS753767  Rabbit G Protein Coupled Receptor 48 ELISA Kit  MBS750952  Bovine G Protein Coupled Receptor 48 ELISA Kit
Products associated with GPR48 elisa kitPathways associated with GPR48 elisa kit
 Reference Product  PubMed Publications
 ZNRF3 elisa kit  >8 publications with GPR48 and ZNRF3
 ATF4 elisa kit  >2 publications with GPR48 and ATF4
 PITX2 elisa kit  >2 publications with GPR48 and PITX2
 ESR1 elisa kit  >1 publications with GPR48 and ESR1
 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway antibodies  RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By WNT In Cancer Pathway antibodies  Signaling By WNT In Cancer Pathway Diagram
 Signaling By Wnt Pathway antibodies  Signaling By Wnt Pathway Diagram
 TCF Dependent Signaling In Response To WNT Pathway antibodies  TCF Dependent Signaling In Response To WNT Pathway Diagram
 XAV939 Inhibits Tankyrase, Stabilizing AXIN Pathway antibodies  XAV939 Inhibits Tankyrase, Stabilizing AXIN Pathway Diagram
 Misspliced LRP5 Mutants Have Enhanced Beta-catenin-dependent Signaling Pathway antibodies  Misspliced LRP5 Mutants Have Enhanced Beta-catenin-dependent Signaling Pathway Diagram
 Regulation Of FZD By Ubiquitination Pathway antibodies  Regulation Of FZD By Ubiquitination Pathway Diagram
Diseases associated with GPR48 elisa kitOrgans/Tissues associated with GPR48 elisa kit
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >4 publications with GPR48 and Kidney Diseases
 Infertility, Female Antibodies  >3 publications with GPR48 and Infertility, Female
 Inflammation Antibodies  >3 publications with GPR48 and Inflammation
 Neoplasms, Experimental Antibodies  >2 publications with GPR48 and Neoplasms, Experimental
 Disease Models, Animal Antibodies  >2 publications with GPR48 and Disease Models, Animal
 Liver Diseases Antibodies  >1 publications with GPR48 and Liver Diseases
 Abnormalities, Drug-Induced Antibodies  >1 publications with GPR48 and Abnormalities, Drug-Induced
 Necrosis Antibodies  >1 publications with GPR48 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >13 publications with GPR48 and Kidney
 Intestine Antibodies  >9 publications with GPR48 and Intestine
 Embryonic Tissue Antibodies  >8 publications with GPR48 and Embryonic Tissue
 Liver Antibodies  >7 publications with GPR48 and Liver
 Testis Antibodies  >7 publications with GPR48 and Testis
 Eye Antibodies  >7 publications with GPR48 and Eye
 Brain Antibodies  >7 publications with GPR48 and Brain
 Skin Antibodies  >6 publications with GPR48 and Skin
 Ovary Antibodies  >5 publications with GPR48 and Ovary
 Muscle Antibodies  >4 publications with GPR48 and Muscle
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