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IGFBP-1 elisa kit :: Porcine Insulin Like Growth Factor Binding Protein 1 (IGFBP-1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS262893
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $315 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Insulin Like Growth Factor Binding Protein 1 (IGFBP-1), ELISA Kit

★Popular Item★
 Also Known As   

Porcine Insulin Like Growth Factor Binding Protein 1 (IGFBP-1) ELISA Kit

 Product Gene Name   

IGFBP-1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    146730
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 Species Reactivity    Porcine
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 Specificity    No cross-reaction with other factors.
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 Samples    Porcine serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant IGFBP-1 concentration
 Assay Type    Sandwich
 Detection Range    10 ng/ml-0.156 ng/ml
 Sensitivity    0.05 ng/ml.
 Intra-assay Precision    <= 8%
 Inter-assay Precision    <= 12%
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IGFBP-1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IGFBP-1 purchase    MBS262893 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Insulin Like Growth Factor Binding Protein 1 (IGFBP-1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 10 ng/ml-0.156 ng/ml in biological research samples containing IGFBP-1, with an estimated sensitivity of 0.05 ng/ml. The ELISA analytical biochemical technique of the MBS262893 kit is based on IGFBP-1 antibody-IGFBP-1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IGFBP-1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IGFBP-1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Porcine serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant IGFBP-1 concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for IGFBP-1 elisa kit

   Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Porcine IGFBP-1 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Testing Data/Standard Curve (for reference only) of IGFBP-1 elisa kit    IGFBP-1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS262893. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IGFBP-1. It may not necessarily be applicable to this product.
 NCBI GI #    4504615
 NCBI GeneID    3484
 NCBI Accession #    NP_000587.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000596.2 [Other Products]
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 UniProt Secondary Accession #    Q8IYP5; A4D2F4; D3DVL9 [Other Products]
 UniProt Related Accession #    P08833 [Other Products]
 Molecular Weight    27,904 Da
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 NCBI Official Full Name    insulin-like growth factor-binding protein 1
 NCBI Official Synonym Full Names    insulin-like growth factor binding protein 1
 NCBI Official Symbol    IGFBP1 [Similar Products]
 NCBI Official Synonym Symbols   
AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1
[Similar Products]
 NCBI Protein Information    insulin-like growth factor-binding protein 1; IBP-1; IGFBP-1; binding protein-25; binding protein-26; binding protein-28; placental protein 12; IGF-binding protein 1; amniotic fluid binding protein; growth hormone independent-binding protein; alpha-pregnancy-associated endometrial globulin
 UniProt Protein Name    Insulin-like growth factor-binding protein 1
 UniProt Synonym Protein Names   
Placental protein 12; PP12
 UniProt Gene Name    IGFBP1 [Similar Products]
 UniProt Synonym Gene Names    IBP1; IBP-1; IGF-binding protein 1; IGFBP-1; PP12 [Similar Products]
 UniProt Entry Name    IBP1_HUMAN
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 NCBI Summary for IGFBP-1    This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IGFBP-1    IGFBP1: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7p12.3

Cellular Component: extracellular space; extracellular region

Molecular Function: insulin-like growth factor binding; insulin-like growth factor I binding; insulin-like growth factor II binding

Biological Process: unfolded protein response, activation of signaling protein activity; regulation of insulin-like growth factor receptor signaling pathway; cellular protein metabolic process; tissue regeneration; unfolded protein response; insulin receptor signaling pathway; signal transduction; positive regulation of cell growth
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 Research Articles on IGFBP-1    1. According to this study IGFBP-1 is a specific marker for preterm delivery in pregnant women with clinical symptoms.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IGFBP-1 elisa kitPathways associated with IGFBP-1 elisa kit
 Reference Product  PubMed Publications
 IGFBP4 elisa kit  >143 publications with IGFBP-1 and IGFBP4
 IGF1 elisa kit  >60 publications with IGFBP-1 and IGF1
 FOXO1 elisa kit  >38 publications with IGFBP-1 and FOXO1
 IGF2 elisa kit  >25 publications with IGFBP-1 and IGF2
 FOXA2 elisa kit  >8 publications with IGFBP-1 and FOXA2
 INS elisa kit  >4 publications with IGFBP-1 and INS
 ATF4 elisa kit  >3 publications with IGFBP-1 and ATF4
 HIF1A elisa kit  >2 publications with IGFBP-1 and HIF1A
 NR3C1 elisa kit  >1 publications with IGFBP-1 and NR3C1
 Products by Pathway  Pathway Diagram
 Activation Of Genes By ATF4 Pathway antibodies  Activation Of Genes By ATF4 Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 HIF-1-alpha Transcription Factor Network Pathway antibodies  HIF-1-alpha Transcription Factor Network Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 PERK Regulated Gene Expression Pathway antibodies  PERK Regulated Gene Expression Pathway Diagram
 Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies  Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram
 Unfolded Protein Response Pathway antibodies  Unfolded Protein Response Pathway Diagram
Diseases associated with IGFBP-1 elisa kitOrgans/Tissues associated with IGFBP-1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >379 publications with IGFBP-1 and Neoplasms
 Liver Diseases Antibodies  >127 publications with IGFBP-1 and Liver Diseases
 Cardiovascular Diseases Antibodies  >114 publications with IGFBP-1 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >85 publications with IGFBP-1 and Disease Models, Animal
 Kidney Diseases Antibodies  >82 publications with IGFBP-1 and Kidney Diseases
 Liver Neoplasms Antibodies  >80 publications with IGFBP-1 and Liver Neoplasms
 Adenocarcinoma Antibodies  >79 publications with IGFBP-1 and Adenocarcinoma
 Brain Diseases Antibodies  >72 publications with IGFBP-1 and Brain Diseases
 Necrosis Antibodies  >62 publications with IGFBP-1 and Necrosis
 Inflammation Antibodies  >59 publications with IGFBP-1 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1274 publications with IGFBP-1 and Blood
 Liver Antibodies  >429 publications with IGFBP-1 and Liver
 Uterus Antibodies  >310 publications with IGFBP-1 and Uterus
 Placenta Antibodies  >229 publications with IGFBP-1 and Placenta
 Embryonic Tissue Antibodies  >123 publications with IGFBP-1 and Embryonic Tissue
 Bone Antibodies  >91 publications with IGFBP-1 and Bone
 Brain Antibodies  >84 publications with IGFBP-1 and Brain
 Lung Antibodies  >44 publications with IGFBP-1 and Lung
 Pancreas Antibodies  >29 publications with IGFBP-1 and Pancreas
 Skin Antibodies  >29 publications with IGFBP-1 and Skin
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