NP_057416.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12,760 Da
NCBI Official Full Name
methionine-R-sulfoxide reductase B1
NCBI Official Synonym Full Names
methionine sulfoxide reductase B1
NCBI Official Synonym Symbols
SELR; SELX; SepR; SEPX1; HSPC270 [Similar Products]
NCBI Protein Information
methionine-R-sulfoxide reductase B1; selenoprotein R; selenoprotein X, 1
UniProt Protein Name
Methionine-R-sulfoxide reductase B1
UniProt Synonym Protein Names
Selenoprotein X; SelX
UniProt Synonym Gene Names
UniProt Entry Name
MSRB1_HUMAN
NCBI Summary for SEPX1
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein belongs to the methionine sulfoxide reductase (Msr) protein family which includes repair enzymes that reduce oxidized methionine residues in proteins. The protein encoded by this gene is expressed in a variety of adult and fetal tissues and localizes to the cell nucleus and cytosol. [provided by RefSeq, Mar 2012]
UniProt Comments for SEPX1
SEPX1: a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein belongs to the methionine sulfoxide reductase (Msr) protein family which includes repair enzymes that reduce oxidized methionine residues in proteins. The protein encoded by this gene is expressed in a variety of adult and fetal tissues and localizes to the cell nucleus and cytosol. [provided by RefSeq, Mar 2012]
Protein type: Oxidoreductase; EC 1.8.4.-
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: cytoplasm; nucleus; actin cytoskeleton
Molecular Function: zinc ion binding; peptide-methionine (R)-S-oxide reductase activity; actin binding
Biological Process: protein repair; actin filament polymerization; innate immune response; response to oxidative stress
Research Articles on SEPX1
Precautions
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Products associated with SEPX1 elisa kit
Pathways associated with SEPX1 elisa kit
Diseases associated with SEPX1 elisa kit
Organs/Tissues associated with SEPX1 elisa kit
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