AAA65605.1
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UniProt Secondary Accession #
Molecular Weight
42,697 Da
NCBI Official Full Name
octamer binding transcription factor 1
UniProt Protein Name
POU domain, class 4, transcription factor 1
UniProt Synonym Protein Names
Brain-specific homeobox/POU domain protein 3A; Brain-3A; Brn-3A; Homeobox/POU domain protein RDC-1; Oct-T1
UniProt Synonym Gene Names
UniProt Entry Name
PO4F1_HUMAN
UniProt Comments for OBTF1
POU4F1: Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons. Belongs to the POU transcription factor family. Class- 4 subfamily.
Protein type: DNA-binding; Transcription factor; Cell development/differentiation
Chromosomal Location of Human Ortholog: 13q31.1
Cellular Component: neuron projection; nuclear chromatin
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding
Biological Process: transcription from RNA polymerase II promoter; trigeminal nerve development; central nervous system neuron differentiation; positive regulation of apoptosis; negative regulation of transcription from RNA polymerase II promoter; habenula development; peripheral nervous system neuron development; cell migration in hindbrain; proprioception during equilibrioception; synaptogenesis; regulation of neurogenesis; axonogenesis; suckling behavior; neuron fate specification; positive regulation of transcription from RNA polymerase II promoter; mesoderm development; sensory system development; negative regulation of neuron apoptosis
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