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RIPK3 elisa kit :: Porcine Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9352244 RIPK3 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3), ELISA Kit

★Popular Item★
 Also Known As   

Porcine Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3) ELISA Kit

 Product Gene Name   

RIPK3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    605817
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 Species Reactivity    Porcine
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Quantitative Sandwich
 Detection Range    0.25 ng/ml - 8 ng/ml
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of RIPK3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RIPK3 purchase    MBS9352244 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.25 ng/ml - 8 ng/ml in biological research samples containing RIPK3, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9352244 kit is based on RIPK3 antibody-RIPK3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RIPK3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RIPK3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for RIPK3 elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RIPK3 (hereafter termed "analyte") in undiluted original Porcine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9352244. Click to request current manual
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NCBI/Uniprot data below describe general gene information for RIPK3. It may not necessarily be applicable to this product.
 NCBI GI #    40254844
 NCBI GeneID    11035
 NCBI Accession #    NP_006862.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006871.3 [Other Products]
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 UniProt Secondary Accession #    Q5J795; Q5J796; Q6P5Y1; B4DJL9; C4AM87 [Other Products]
 UniProt Related Accession #    Q9Y572 [Other Products]
 Molecular Weight    25,326 Da
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 NCBI Official Full Name    receptor-interacting serine/threonine-protein kinase 3
 NCBI Official Synonym Full Names    receptor interacting serine/threonine kinase 3
 NCBI Official Symbol    RIPK3 [Similar Products]
 NCBI Official Synonym Symbols   
RIP3
[Similar Products]
 NCBI Protein Information    receptor-interacting serine/threonine-protein kinase 3
 UniProt Protein Name    Receptor-interacting serine/threonine-protein kinase 3
 UniProt Synonym Protein Names   
RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3
 Protein Family    Receptor-interacting serine/threonine-protein kinase
 UniProt Gene Name    RIPK3 [Similar Products]
 UniProt Synonym Gene Names    RIP3; RIP-3 [Similar Products]
 UniProt Entry Name    RIPK3_HUMAN
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 NCBI Summary for RIPK3    The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008]
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 UniProt Comments for RIPK3    RIPK3: Promotes apoptosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Binds TRAF2 and RIPK1 and is recruited to the TNFR-1 signaling complex. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, TKL; EC 2.7.11.1; TKL group; RIPK family

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: cytosol; mitochondrion; plasma membrane

Molecular Function: ATP binding; identical protein binding; NF-kappaB-inducing kinase activity; protein binding; protein complex binding; protein kinase activity; protein serine/threonine kinase activity; transcription coactivator activity

Biological Process: activation of NF-kappaB transcription factor; activation of protein kinase activity; I-kappaB kinase/NF-kappaB cascade; innate immune response; lymph node development; MyD88-independent toll-like receptor signaling pathway; positive regulation of interferon type I production; positive regulation of ligase activity; positive regulation of oxidoreductase activity; programmed cell death; protein amino acid autophosphorylation; protein heterooligomerization; protein homooligomerization; protein modification process; regulation of activated T cell proliferation; regulation of adaptive immune response; regulation of interferon-gamma production; regulation of T cell mediated cytotoxicity; signal transduction; spleen development; T cell differentiation in the thymus; T cell homeostasis; thymus development; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor signaling pathway
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 Research Articles on RIPK3    1. The RIP3 expression is reduced in tumors compared to normal tissue in 85% of breast cancer patients, suggesting that RIP3 deficiency is positively selected during tumor growth/development.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with RIPK3 elisa kitPathways associated with RIPK3 elisa kit
 Reference Product  PubMed Publications
 RIPK1 elisa kit  >141 publications with RIPK3 and RIPK1
 CASP8 elisa kit  >109 publications with RIPK3 and CASP8
 MLKL elisa kit  >94 publications with RIPK3 and MLKL
 FADD elisa kit  >56 publications with RIPK3 and FADD
 TLR3 elisa kit  >7 publications with RIPK3 and TLR3
 ZBP1 elisa kit  >6 publications with RIPK3 and ZBP1
 TICAM1 elisa kit  >3 publications with RIPK3 and TICAM1
 Products by Pathway  Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic Sensors Of Pathogen-associated DNA Pathway antibodies  Cytosolic Sensors Of Pathogen-associated DNA Pathway Diagram
 IKK Complex Recruitment Mediated By RIP1 Pathway antibodies  IKK Complex Recruitment Mediated By RIP1 Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 MyD88-independent TLR3/TLR4 Cascade Pathway antibodies  MyD88-independent TLR3/TLR4 Cascade Pathway Diagram
 Programmed Cell Death Pathway antibodies  Programmed Cell Death Pathway Diagram
 RIP-mediated NFkB Activation Via ZBP1 Pathway antibodies  RIP-mediated NFkB Activation Via ZBP1 Pathway Diagram
Diseases associated with RIPK3 elisa kitOrgans/Tissues associated with RIPK3 elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >262 publications with RIPK3 and Necrosis
 Inflammation Antibodies  >109 publications with RIPK3 and Inflammation
 Cardiovascular Diseases Antibodies  >23 publications with RIPK3 and Cardiovascular Diseases
 Vascular Diseases Antibodies  >21 publications with RIPK3 and Vascular Diseases
 Liver Diseases Antibodies  >19 publications with RIPK3 and Liver Diseases
 Hypertension Antibodies  >13 publications with RIPK3 and Hypertension
 Drug-Induced Liver Injury Antibodies  >10 publications with RIPK3 and Drug-Induced Liver Injury
 Heart Diseases Antibodies  >8 publications with RIPK3 and Heart Diseases
 Acute Kidney Injury Antibodies  >8 publications with RIPK3 and Acute Kidney Injury
 Drug-Related Side Effects and Adverse Reactions Antibodies  >7 publications with RIPK3 and Drug-Related Side Effects and Adverse Reactions
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >40 publications with RIPK3 and Blood
 Liver Antibodies  >30 publications with RIPK3 and Liver
 Brain Antibodies  >17 publications with RIPK3 and Brain
 Intestine Antibodies  >14 publications with RIPK3 and Intestine
 Kidney Antibodies  >13 publications with RIPK3 and Kidney
 Heart Antibodies  >12 publications with RIPK3 and Heart
 Skin Antibodies  >11 publications with RIPK3 and Skin
 Lung Antibodies  >9 publications with RIPK3 and Lung
 Muscle Antibodies  >8 publications with RIPK3 and Muscle
 Vascular Antibodies  >6 publications with RIPK3 and Vascular
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