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RENIN elisa kit :: Porcine Renin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS013851 RENIN elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Renin, ELISA Kit

★Popular Item★
 Also Known As   

Porcine Renin ELISA Kit

 Product Gene Name   

RENIN elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 1; NC_000001.10 (204123944..204135465, complement). Location: 1q32
 OMIM    179820
 3D Structure    ModBase 3D Structure for P00797
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 Species Reactivity    Porcine
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    31.2 pg/ml - 1000 pg/ml
 Sensitivity    5.0 pg/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of RENIN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RENIN purchase    MBS013851 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Renin, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.2 pg/ml - 1000 pg/ml in biological research samples containing RENIN, with an estimated sensitivity of 5.0 pg/ml. The ELISA analytical biochemical technique of the MBS013851 kit is based on RENIN antibody-RENIN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RENIN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RENIN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for RENIN elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RENIN (hereafter termed "analyte") in undiluted original Porcine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS013851. Click to request current manual
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NCBI/Uniprot data below describe general gene information for RENIN. It may not necessarily be applicable to this product.
 NCBI GI #    4506475
 NCBI GeneID    5972
 NCBI Accession #    NP_000528.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000537.3 [Other Products]
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 UniProt Primary Accession #    P00797 [Other Products]
 UniProt Secondary Accession #    Q6FI38; Q6T5C2 [Other Products]
 UniProt Related Accession #    P00797 [Other Products]
 Molecular Weight    45,057 Da
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 NCBI Official Full Name    renin preproprotein
 NCBI Official Synonym Full Names    renin
 NCBI Official Symbol    REN [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    renin; angiotensinogenase; renin precursor, renal; angiotensin-forming enzyme
 UniProt Protein Name    Renin
 UniProt Synonym Protein Names   
 Protein Family    Renin
 UniProt Gene Name    REN [Similar Products]
 UniProt Entry Name    RENI_HUMAN
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 NCBI Summary for RENIN    Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]
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 UniProt Comments for RENIN    REN: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Interacts with ATP6AP2. Interaction with ATP6AP2 results in a 5-fold increased efficiency in angiotensinogen processing. Belongs to the peptidase A1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Protease; EC

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: extracellular space; cytoplasm; plasma membrane; extracellular region

Molecular Function: peptidase activity; insulin-like growth factor receptor binding; aspartic-type endopeptidase activity; receptor binding

Biological Process: response to cAMP; hormone-mediated signaling; cell maturation; drinking behavior; male gonad development; renin-angiotensin regulation of aldosterone production; response to lipopolysaccharide; proteolysis; angiotensin maturation; cellular protein metabolic process; regulation of MAPKKK cascade; regulation of blood pressure; beta-amyloid metabolic process; mesonephros development; kidney development

Disease: Renal Tubular Dysgenesis; Hyperuricemic Nephropathy, Familial Juvenile, 2
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 Research Articles on RENIN    1. Aldosterone rise that often occurs during prolonged renin-angiotensin system blockade is rather due to the angiotensin II 'escape' during such blockade.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with RENIN elisa kitPathways associated with RENIN elisa kit
 Reference Product  PubMed Publications
 ACE elisa kit  >129 publications with RENIN and ACE
 PTGS2 elisa kit  >61 publications with RENIN and PTGS2
 AGT elisa kit  >53 publications with RENIN and AGT
 INS elisa kit  >25 publications with RENIN and INS
 NOS3 elisa kit  >20 publications with RENIN and NOS3
 ATP6AP2 elisa kit  >4 publications with RENIN and ATP6AP2
 RENBP elisa kit  >2 publications with RENIN and RENBP
 DIF elisa kit  >1 publications with RENIN and DIF
 EDN1 elisa kit  >1 publications with RENIN and EDN1
 KNG1 elisa kit  >1 publications with RENIN and KNG1
 Products by Pathway  Pathway Diagram
 ACE Inhibitor Pathway antibodies  ACE Inhibitor Pathway Diagram
 Metabolism Of Angiotensinogen To Angiotensins Pathway antibodies  Metabolism Of Angiotensinogen To Angiotensins Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
Diseases associated with RENIN elisa kitOrgans/Tissues associated with RENIN elisa kit
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >3895 publications with RENIN and Kidney Diseases
 Renal Insufficiency Antibodies  >2637 publications with RENIN and Renal Insufficiency
 Hypertension Antibodies  >1076 publications with RENIN and Hypertension
 Heart Diseases Antibodies  >941 publications with RENIN and Heart Diseases
 Acute Kidney Injury Antibodies  >796 publications with RENIN and Acute Kidney Injury
 Necrosis Antibodies  >762 publications with RENIN and Necrosis
 Drug Toxicity Antibodies  >743 publications with RENIN and Drug Toxicity
 Hypertension, Renal Antibodies  >557 publications with RENIN and Hypertension, Renal
 Ischemia Antibodies  >517 publications with RENIN and Ischemia
 Proteinuria Antibodies  >442 publications with RENIN and Proteinuria
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >4947 publications with RENIN and Kidney
 Lung Antibodies  >822 publications with RENIN and Lung
 Skin Antibodies  >442 publications with RENIN and Skin
 Intestine Antibodies  >274 publications with RENIN and Intestine
 Embryonic Tissue Antibodies  >200 publications with RENIN and Embryonic Tissue
 Pancreas Antibodies  >115 publications with RENIN and Pancreas
 Bladder Antibodies  >115 publications with RENIN and Bladder
 Testis Antibodies  >110 publications with RENIN and Testis
 Ovary Antibodies  >96 publications with RENIN and Ovary
 Placenta Antibodies  >69 publications with RENIN and Placenta
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