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S100B elisa kit :: Porcine S100B ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2501779
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $400 +1 FREE 8GB USB
96-Strip-Wells  /  $475 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,975 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,480 +4 FREE 8GB USB
 
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 Product Name   

S100B, ELISA Kit

★Popular Item★
 Also Known As   

Porcine S100B (S100 Calcium Binding Protein B) ELISA Kit

 Product Gene Name   

S100B elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2501779 COA    COA PDF
 OMIM    176990
 3D Structure    ModBase 3D Structure for P04271
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 Species Reactivity    Porcine
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 Specificity    This kit recognizes natural and some recombinant Porcine S100B. No significant crossreactivity or interference between Porcine S100B and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.156-10ng/mL
 Sensitivity    Min: 0.094ng/mL; Max: 10ng/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Porcine S100B were tested 20 times on one plate, respectively.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Porcine S100B were tested on 3 different plates, 20 replicates in each plate.
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of S100B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for S100B purchase    MBS2501779 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the S100B, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10ng/mL in biological research samples containing S100B, with an estimated sensitivity of Min: 0.094ng/mL; Max: 10ng/mL. The ELISA analytical biochemical technique of the MBS2501779 kit is based on S100B antibody-S100B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect S100B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, S100B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for S100B elisa kit

   Intended Uses: This ELISA kit can be applied to the in vitro quantitative determination of Porcine S100B concentrations in serum, plasma and other biological fluids.
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 Typical Testing Data/Standard Curve (for reference only) of S100B elisa kit    S100B elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2501779. Click to request current manual
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NCBI/Uniprot data below describe general gene information for S100B. It may not necessarily be applicable to this product.
 NCBI GI #    49457242
 NCBI GeneID    6285
 NCBI Accession #    CAG46920.1 [Other Products]
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 UniProt Primary Accession #    P04271 [Other Products]
 UniProt Secondary Accession #    D3DSN6 [Other Products]
 UniProt Related Accession #    P04271 [Other Products]
 Molecular Weight    10,713 Da
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 NCBI Official Full Name    S100B
 NCBI Official Synonym Full Names    S100 calcium binding protein B
 NCBI Official Symbol    S100B [Similar Products]
 NCBI Official Synonym Symbols   
NEF; S100; S100-B; S100beta
[Similar Products]
 NCBI Protein Information    protein S100-B; S-100 calcium-binding protein, beta chain; S-100 protein subunit beta; S100 calcium-binding protein, beta (neural)
 UniProt Protein Name    Protein S100-B
 UniProt Synonym Protein Names   
S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B
 Protein Family    Protein
 UniProt Gene Name    S100B [Similar Products]
 UniProt Entry Name    S100B_HUMAN
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 NCBI Summary for S100B    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
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 UniProt Comments for S100B    S100B: Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain. The S100B dimer binds two molecules of STK38. Interacts with AGER. The S100B dimer interacts with two molecules of CAPZA1. Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues. Belongs to the S-101 family.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: ruffle; extracellular space; intracellular membrane-bound organelle; cell soma; perinuclear region of cytoplasm; cytoplasm; extracellular region; nucleus

Molecular Function: identical protein binding; RAGE receptor binding; protein binding; protein homodimerization activity; zinc ion binding; calcium ion binding; calcium-dependent protein binding; tau protein binding

Biological Process: central nervous system development; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptosis; response to glucocorticoid stimulus; memory; regulation of cell shape; cell proliferation; learning and/or memory; astrocyte differentiation; axonogenesis; response to methylmercury; positive regulation of cell proliferation; innate immune response; regulation of neuronal synaptic plasticity
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 Research Articles on S100B    1. Measurement serum S100B could be useful to detect cerebral complications in deeply sedated patients associated with ECMO but not for monitoring delirium after sedation withdrawal.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with S100B elisa kitPathways associated with S100B elisa kit
 Reference Product  PubMed Publications
 GFAP elisa kit  >166 publications with S100B and GFAP
 S100A1 elisa kit  >92 publications with S100B and S100A1
 APP elisa kit  >17 publications with S100B and APP
 TP53 elisa kit  >5 publications with S100B and TP53
 IQGAP1 elisa kit  >3 publications with S100B and IQGAP1
 AHNAK elisa kit  >3 publications with S100B and AHNAK
 ANXA6 elisa kit  >1 publications with S100B and ANXA6
 STK38 elisa kit  >1 publications with S100B and STK38
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 Advanced Glycosylation Endproduct Receptor Signaling Pathway antibodies  Advanced Glycosylation Endproduct Receptor Signaling Pathway Diagram
 Cytosolic Sensors Of Pathogen-associated DNA Pathway antibodies  Cytosolic Sensors Of Pathogen-associated DNA Pathway Diagram
 DEx/H-box Helicases Activate Type I IFN And Inflammatory Cytokines Production Pathway antibodies  DEx/H-box Helicases Activate Type I IFN And Inflammatory Cytokines Production Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 MyD88 Cascade Initiated On Plasma Membrane Pathway antibodies  MyD88 Cascade Initiated On Plasma Membrane Pathway Diagram
 MyD88 Dependent Cascade Initiated On Endosome Pathway antibodies  MyD88 Dependent Cascade Initiated On Endosome Pathway Diagram
 MyD88-independent Cascade Pathway antibodies  MyD88-independent Cascade Pathway Diagram
 MyD88:Mal Cascade Initiated On Plasma Membrane Pathway antibodies  MyD88:Mal Cascade Initiated On Plasma Membrane Pathway Diagram
Diseases associated with S100B elisa kitOrgans/Tissues associated with S100B elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >642 publications with S100B and Nervous System Diseases
 Brain Diseases Antibodies  >529 publications with S100B and Brain Diseases
 Cardiovascular Diseases Antibodies  >236 publications with S100B and Cardiovascular Diseases
 Brain Injuries Antibodies  >186 publications with S100B and Brain Injuries
 Inflammation Antibodies  >140 publications with S100B and Inflammation
 Brain Ischemia Antibodies  >116 publications with S100B and Brain Ischemia
 Disease Models, Animal Antibodies  >111 publications with S100B and Disease Models, Animal
 Hemorrhage Antibodies  >78 publications with S100B and Hemorrhage
 Heart Diseases Antibodies  >68 publications with S100B and Heart Diseases
 Necrosis Antibodies  >57 publications with S100B and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1027 publications with S100B and Nerve
 Brain Antibodies  >911 publications with S100B and Brain
 Blood Antibodies  >744 publications with S100B and Blood
 Heart Antibodies  >114 publications with S100B and Heart
 Skin Antibodies  >60 publications with S100B and Skin
 Lung Antibodies  >34 publications with S100B and Lung
 Eye Antibodies  >33 publications with S100B and Eye
 Spinal Cord Antibodies  >25 publications with S100B and Spinal Cord
 Embryonic Tissue Antibodies  >15 publications with S100B and Embryonic Tissue
 Adipose Tissue Antibodies  >9 publications with S100B and Adipose Tissue
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