NP_068739.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
13,016 Da
NCBI Official Full Name
secretin preproprotein
NCBI Official Synonym Full Names
secretin
NCBI Protein Information
secretin; prepro-secretin
UniProt Protein Name
Secretin
UniProt Entry Name
SECR_HUMAN
NCBI Summary for SCT
Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion. [provided by RefSeq, Jul 2008]
UniProt Comments for SCT
SCT: Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach. Belongs to the glucagon family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11p15.5
Cellular Component: extracellular region
Molecular Function: hormone activity
Biological Process: dentate gyrus development; visual learning; negative regulation of neuron apoptosis; pancreatic juice secretion
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Products associated with SCT elisa kit
Pathways associated with SCT elisa kit
Diseases associated with SCT elisa kit
Organs/Tissues associated with SCT elisa kit
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